Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 14/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772313 | 0.95 | KIF11 (0.59) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| Lithium Ion SCHEMBL8852232 | 0.95 | KIF11 (0.59) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| Tetramethylammonium Ion SCHEMBL6517997 | 0.90 | KIF11 (0.53) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| Tetrylammonium SCHEMBL374839 | 0.85 | KIF11 (0.48) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| Paraquat SCHEMBL8852739 | 0.80 | SLC22A2 (0.50) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| Tetrabuthylammonium SCHEMBL1350363 | 0.80 | KIF11 (0.44) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8350816 | 0.79 | KIF11 (0.43) | KIF11CYP3A4 | |
| Choline SCHEMBL9015229 | 0.79 | KIF11 (0.43) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1149158 | 0.77 | KIF11 (0.64) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| Cetrimonium SCHEMBL9771956 | 0.77 | DNM1 (0.44) | KIF11KCNH2CYP3A4CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6190824-B1 | POLYMERIZABLE MONOMER, A PHOTOPOLYMERIZATION INITIATOR, AND A DIAZONIUM SALT HAVING A SPECIFIC, BORON ANION PORTION | FUJI PHOTO FILM CO., LTD. (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0599993-B1 | A HARD COPY IMAGING SYSTEM | EASTMAN KODAK CO (US) | 1995-08-02 | — | — | EP | disclosed |
| EP-0339841-B1 | Photosensitive compositions and materials | MEAD CORP (US) | 1995-07-05 | — | — | EP | disclosed |
| EP-0389067-B1 | Ionic dye compounds | MEAD CORP (US) | 1994-10-19 | — | — | EP | disclosed |
| EP-0599993-A1 | A HARD COPY IMAGING SYSTEM. | EASTMAN KODAK CO (US) | 1994-06-08 | — | — | EP | disclosed |
| US-5252425-A | Hard copy imaging system | EASTMAN KODAK COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| WO-1993003927-A1 | A HARD COPY IMAGING SYSTEM | EASTMAN KODAK COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |
| US-5151520-A | Cyanine, carbocyanine, hemicyanine, rhodamine and azamethine dyes | THE MEAD CORPORATION (US) | 1992-09-29 | — | — | US | disclosed |
| US-5035621-A | Photohardenable Dental Adhesive | MEAD CORPORATION (US) | 1991-07-30 | — | — | US | disclosed |
| EP-0434437-A2 | Photohardenable or thermohardenable compositions and photosensitive materials utilising such photohardenable compositions | THE MEAD CORPORATION (US) | 1991-06-26 | — | — | EP | disclosed |
| US-4842980-A | ABSORBING ACTINIC RADIATION AND PRODUCING FREE RADICALS | THE MEAD CORPORATION (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0301769-A2 | Radiation-curable compositions and their use for printing and coating | THE MEAD CORPORATION (US) | 1989-02-01 | — | — | EP | disclosed |
| US-4801392-A | FREE RADICAL POLYMERIZATION OR CROSSLINKING | THE MEAD CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |
| US-4800149-A | FREE RADICAL GENERATION AND CROSSLINKING | THE MEAD CORPORATION (US) | 1989-01-24 | — | — | US | disclosed |
| US-4788124-A | IONIC DYE-REACTIVE COUNTER ION COMPOUND | THE MEAD CORPORATION (US) | 1988-11-29 | — | — | US | disclosed |
| US-4772530-A | XANTHENE AND OXONOL DYES | THE MEAD CORPORATION (US) | 1988-09-20 | — | — | US | disclosed |
| US-4772541-A | SENSITIVE AT LONGER WAVELENGTHS | THE MEAD CORPORATION (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0277034-A2 | Lamination of two substrates | THE MEAD CORPORATION (US) | 1988-08-03 | — | — | EP | disclosed |
| US-4751102-A | FOR PHOTOHARDENABLE FREE RADICAL ADDITION POLYMERIZABLE OR CROSSLINKABLE COMPOUND | THE MEAD CORPORATION (US) | 1988-06-14 | — | — | US | disclosed |
| EP-0223587-A1 | Photosensitive materials containing ionic dye compounds as initiators | THE MEAD CORPORATION (US) | 1987-05-27 | — | — | EP | disclosed |