Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487048 | 0.96 | TSHR (0.44) | TSHRALDH1A1CYP3A4ALOX15HTR6 | |
| SCHEMBL29575161 | 0.96 | TSHR (0.44) | TSHRALDH1A1CYP3A4ALOX15HTR6 | |
| Lithium Ion SCHEMBL28830257 | 0.96 | TSHR (0.44) | TSHRALDH1A1CYP3A4ALOX15HTR6 | |
| Potassium Ion SCHEMBL29386357 | 0.83 | L3MBTL1 (0.44) | TSHRALDH1A1CYP3A4ALOX15HTR6 | |
| Potassium Ion SCHEMBL6028409 | 0.83 | L3MBTL1 (0.44) | TSHRALDH1A1CYP3A4ALOX15HTR6 | |
| Potassium Ion SCHEMBL7064776 | 0.83 | NR4A1 (0.42) | ALDH1A1CYP3A4HTR6PKMRECQL | |
| SCHEMBL7098523 | 0.80 | L3MBTL1 (0.45) | TSHRALDH1A1CYP3A4ALOX15HTR6 | |
| SCHEMBL9294471 | 0.79 | CDC25B (0.55) | TSHRALDH1A1CYP3A4ALOX15HTR6 | |
| Potassium Ion SCHEMBL8394449 | 0.79 | L3MBTL1 (0.50) | TSHRALDH1A1CYP3A4ALOX15HTR6 | |
| Lithium Ion SCHEMBL8489528 | 0.78 | P2RY12 (0.42) | TSHRALDH1A1CYP3A4HTR6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116219085-A | Synthetic tanning agent containing multifunctional structure and preparation method and application thereof | 南京工业大学 | 2023-06-06 | — | — | CN | claimed |
| CN-115521263-A | Polyfunctional group triazine type chromium-free tanning agent and preparation method thereof | 南京工业大学 | 2022-12-27 | — | — | CN | claimed |
| US-12566113-B2 | Reversible fixing reagents and methods of use thereof | 10X GENOMICS, INC. (US) | 2026-03-03 | — | — | US | disclosed |
| EP-4081777-B1 | REVERSIBLE FIXING REAGENTS AND METHODS OF USE THEREOF | 10X GENOMICS INC (US) | 2026-02-18 | — | — | EP | disclosed |
| US-20250216300-A1 | REVERSIBLE FIXING REAGENTS AND METHODS OF USE THEREOF | 10X GENOMICS, INC. | 2025-07-03 | — | — | US | disclosed |
| US-12241890-B2 | Methods for generating barcoded nucleic acid molecules using fixed cells | 10X GENOMICS, INC. (US) | 2025-03-04 | — | — | US | disclosed |
| CN-115521263-B | Multifunctional triazine type chrome-free tanning agent and preparation method thereof | 南京工业大学 | 2025-02-14 | — | — | CN | disclosed |
| US-20250003956-A1 | COMPOSITIONS AND METHODS FOR USING FIXED BIOLOGICAL SAMPLES IN PARTITION-BASED ASSAYS | 10X GENOMICS, INC. | 2025-01-02 | — | — | US | disclosed |
| US-12117439-B2 | Compositions and methods for using fixed biological samples | 10X GENOMICS, INC. (US) | 2024-10-15 | — | — | US | disclosed |
| CN-118448806-A | Functional aramid nanofiber coated diaphragm and preparation method and application thereof | 华中科技大学 | 2024-08-06 | — | — | CN | disclosed |
| US-20240230483-A1 | CHOP-FIX METHOD AND CHOPPING DEVICE FOR PREPARING BIOLOGICAL SAMPLES | 10X GENOMICS INC (US) | 2024-07-11 | — | — | US | disclosed |
| CN-116219085-A | Synthetic tanning agent containing multifunctional structure and preparation method and application thereof | 南京工业大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-115521263-A | Polyfunctional group triazine type chromium-free tanning agent and preparation method thereof | 南京工业大学 | 2022-12-27 | — | — | CN | disclosed |
| CN-113854286-B | Chlorine dioxide sustained release agent and preparation method and application thereof | 湖南大学 | 2022-12-09 | — | — | CN | disclosed |
| US-20220334031-A1 | REVERSIBLE FIXING REAGENTS AND METHODS OF USE THEREOF | 10X GENOMICS, INC. (US) | 2022-10-20 | — | — | US | disclosed |
| CN-113854286-A | Chlorine dioxide sustained release agent and preparation method and application thereof | 湖南大学 | 2021-12-31 | — | — | CN | disclosed |
| US-20210190770-A1 | COMPOSITIONS AND METHODS FOR USING FIXED BIOLOGICAL SAMPLES IN PARTITION-BASED ASSAYS | 10X GENOMICS, INC. (US) | 2021-06-24 | — | — | US | disclosed |
| EP-1068531-A2 | LIGAND SCREENING AND DESIGN BY X-RAY CRYSTALLOGRAPHY | Abbott Laboratories (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999045389-A2 | LIGAND SCREENING AND DESIGN BY X-RAY CRYSTALLOGRAPHY | ABBOTT LAB (US) | 1999-09-10 | — | — | WO | disclosed |
| WO-1999045379-A2 | LIGAND SCREENING AND DESIGN BY X-RAY CRYSTALLOGRAPHY | ABBOTT LABORATORIES (US) | 1999-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12566113-B2 | Reversible fixing reagents and methods of use thereof | SMCHD1, H1-10, FLT3 | TSHR 1540/4885ALDH1A1 117/4885CYP3A4 706/4885 |
| US-20210190770-A1 | COMPOSITIONS AND METHODS FOR USING FIXED BIOLOGICAL SAMPLES IN PARTITION-BASED ASSAYS | FBL, DIS3, ALKBH1 | TSHR 4416/4885ALDH1A1 2270/4885CYP3A4 3249/4885 |
| US-20220334031-A1 | REVERSIBLE FIXING REAGENTS AND METHODS OF USE THEREOF | PTMS, FGB, CPSF1 | TSHR 3016/4885ALDH1A1 4091/4885CYP3A4 4161/4885 |
| US-12117439-B2 | Compositions and methods for using fixed biological samples | FBL, ALKBH1, NOP2 | TSHR 4575/4885ALDH1A1 2036/4885CYP3A4 3601/4885 |
| US-20250003956-A1 | COMPOSITIONS AND METHODS FOR USING FIXED BIOLOGICAL SAMPLES IN PARTITION-BASED ASSAYS | FBL, DIS3, ALKBH1 | TSHR 4416/4885ALDH1A1 2270/4885CYP3A4 3249/4885 |
| US-12241890-B2 | Methods for generating barcoded nucleic acid molecules using fixed cells | FBL, DUT, ALKBH1 | TSHR 4691/4885ALDH1A1 1509/4885CYP3A4 3689/4885 |
| US-20250216300-A1 | REVERSIBLE FIXING REAGENTS AND METHODS OF USE THEREOF | PTMS, FGB, CPSF1 | TSHR 3016/4885ALDH1A1 4091/4885CYP3A4 4161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.