SCHEMBL7791272

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10584050	0.82	—	—
	SCHEMBL2751793	0.70	HPGD (0.49)	ALDH1A1MAPTPOLBTDP1L3MBTL1
	SCHEMBL6972732	0.69	NOTUM (0.39)	ALDH1A1POLBHTTNPC1RAB9A
	SCHEMBL346321	0.69	ADRA1D (0.49)	ALDH1A1MAPTTHRBHSD17B10MEN1
	SCHEMBL340071	0.68	LOXL2 (0.47)	L3MBTL1NPC1RAB9ASMN1; SMN2
	Detomidine SCHEMBL247340	0.68	ALDH1A1 (0.35)	ALDH1A1POLBMEN1KMT2ACYP2C9
	Detomidine SCHEMBL20362222	0.67	ALDH1A1 (0.34)	ALDH1A1POLBMEN1KMT2AHPGD
	SCHEMBL9686545	0.67	MAPT (0.49)	ALDH1A1MAPTPOLBTDP1L3MBTL1
	Detomidine SCHEMBL203174	0.67	ALDH1A1 (0.34)	ALDH1A1POLBMEN1KMT2AHPGD
	SCHEMBL6972728	0.67	ALDH1A1 (0.42)	ALDH1A1MEN1KMT2AHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.