Rutin

Rutin

SCHEMBL802819

CC1O[C@@H](OCC2O[C@@H](Oc3c(-c4ccc(O)c(O)c4)oc4cc(O)cc(O)c4c3=O)C(O)C(O)[C@@H]2O)C(O)C(O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 1.00
XDH P47989 4/20 1.00
MAOA P21397 3/20 1.00
EPHX2 P34913 3/20 1.00
MAPT P10636 2/20 1.00
HES1 Q14469 2/20 1.00
FANCF Q9NPI8 2/20 1.00
POLB P06746 2/20 1.00
GAA P10253 2/20 1.00
KDM1A O60341 1/20 1.00
PRSS1 P07477 1/20 1.00
PRSS2 P07478 1/20 1.00
ADRA2A P08913 1/20 1.00
HMGB1 P09429 1/20 1.00
CFTR P13569 1/20 1.00
ADRA2C P18825 1/20 1.00
ACHE P22303 1/20 1.00
MAPK1 P28482 1/20 1.00
PRSS3 P35030 1/20 1.00
BACE1 P56817 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rutin SCHEMBL15263233 1.00 KDM4E (1.00) KDM4EXDHMAOAEPHX2MAPT
Rutin SCHEMBL13696608 1.00 KDM4E (1.00) KDM4EXDHMAOAEPHX2MAPT
Rutin SCHEMBL20576343 1.00 KDM4E (1.00) KDM4EXDHMAOAEPHX2MAPT
Rutin SCHEMBL13696392 1.00 KDM4E (1.00) KDM4EXDHMAOAEPHX2MAPT
Rutin SCHEMBL21424757 1.00 KDM4E (1.00) KDM4EXDHMAOAEPHX2MAPT
Rutin SCHEMBL23663918 1.00 KDM4E (1.00) KDM4EXDHMAOAEPHX2MAPT
Rutin SCHEMBL21013017 1.00 KDM4E (1.00) KDM4EXDHMAOAEPHX2MAPT
Rutin SCHEMBL21325433 1.00 KDM4E (1.00) KDM4EXDHMAOAEPHX2MAPT
Rutin SCHEMBL21699244 1.00 KDM4E (1.00) KDM4EXDHMAOAEPHX2MAPT
Rutin SCHEMBL15025698 1.00 KDM4E (1.00) KDM4EXDHMAOAEPHX2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11872241-B2 Compositions and methods for reducing major thrombotic events in cancer patients BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) 2024-01-16 US disclosed
US-20230346833-A1 POROUS SILICATE AND/OR ALUMINOSILICATE MATRIX/CERIUM OXIDE NANOPARITLE NANOCARRIER FOR COMBINATION ANTI-CANCER THERAPEUTIC AND ANTIOXIDANT DELIVERY IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2023-11-02 US disclosed
US-11779652-B2 Porous silicate/magnetic ferrite nanocarrier for combination anti-cancer therapeutic and antioxidant delivery IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2023-10-10 US disclosed
US-20220401572-A1 POROUS SILICATE/MAGNETIC FERRITE NANOCARRIER FOR COMBINATION ANTI-CANCER THERAPEUTIC AND ANTIOXIDANT DELIVERY IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2022-12-22 US disclosed
US-20210220323-A1 COMPOSITIONS COMPRISING COMBINATIONS OF PURIFIED CANNABINOIDS, WITH AT LEAST ONE FLAVONOID, TERPENE OR MINERAL ebbu, Inc. 2021-07-22 US disclosed
US-20200385762-A1 Means and Methods for the Production of Terpenoids UNIVERSITEIT GENT (BE) 2020-12-10 US disclosed
US-20200171064-A1 COMPOSITIONS AND METHODS FOR REDUCING MAJOR THROMBOTIC EVENTS IN CANCER PATIENTS BETH ISRAEL DEACONESS MEDICAL CENTER, INC. 2020-06-04 US disclosed
US-10233206-B2 D-fagomine for the control of inflammatory processes related to an overactivation of the humoral immune response SERGIO PUMAROLA SEGURA (ES) 2019-03-19 US disclosed
US-20170266153-A1 COMPOSITIONS PURPOSEFULLY SELECTED COMPRISING PURIFIED CANNABINOIDS AND/OR PURIFIED TERPENES WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2017-09-21 US disclosed
US-9713624-B1 Synthesis of rutin nanotubes KING SAUD UNIVERSITY (SA) 2017-07-25 US disclosed
US-20120071428-A1 NANOCRYSTALLINE PHOTOCATALYTIC COLLOID, A METHOD OF PRODUCING IT AND ITS USE JAGIELLONIAN UNIVERSITY (PL) 2012-03-22 US disclosed
US-20080139664-A1 ANTI-GLYCATION AGENTS FOR PREVENTING AGE-, DIABETES-, AND SMOKING-RELATED COMPLICATIONS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2008-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200171064-A1 COMPOSITIONS AND METHODS FOR REDUCING MAJOR THROMBOTIC EVENTS IN CANCER PATIENTS SELP, SELE, SELPLG KDM4E 3842/4885XDH 965/4885MAOA 2498/4885
US-20080139664-A1 ANTI-GLYCATION AGENTS FOR PREVENTING AGE-, DIABETES-, AND SMOKING-RELATED COMPLICATIONS AGER, GID4, GALE KDM4E 1615/4885XDH 1066/4885MAOA 197/4885
US-11872241-B2 Compositions and methods for reducing major thrombotic events in cancer patients SELP, SELE, SELPLG KDM4E 3842/4885XDH 965/4885MAOA 2498/4885
US-20120071428-A1 NANOCRYSTALLINE PHOTOCATALYTIC COLLOID, A METHOD OF PRODUCING IT AND ITS USE UROD, CRYZ, CRYAB KDM4E 1774/4885XDH 4649/4885MAOA 1830/4885
US-11779652-B2 Porous silicate/magnetic ferrite nanocarrier for combination anti-cancer therapeutic and antioxidant delivery SLC40A1, AIFM2, FECH KDM4E 2341/4885XDH 1530/4885MAOA 782/4885
US-20220401572-A1 POROUS SILICATE/MAGNETIC FERRITE NANOCARRIER FOR COMBINATION ANTI-CANCER THERAPEUTIC AND ANTIOXIDANT DELIVERY SLC40A1, AIFM2, FECH KDM4E 2341/4885XDH 1530/4885MAOA 782/4885
US-20210220323-A1 COMPOSITIONS COMPRISING COMBINATIONS OF PURIFIED CANNABINOIDS, WITH AT LEAST ONE FLAVONOID, TERPENE OR MINERAL CNR2, CNR1, MAG KDM4E 577/4885XDH 3859/4885MAOA 840/4885
US-10233206-B2 D-fagomine for the control of inflammatory processes related to an overactivation of the humoral immune response TLR5, CD74, FCGR1A KDM4E 4876/4885XDH 1788/4885MAOA 195/4885
US-20230346833-A1 POROUS SILICATE AND/OR ALUMINOSILICATE MATRIX/CERIUM OXIDE NANOPARITLE NANOCARRIER FOR COMBINATION ANTI-CANCER THERAPEUTIC AND ANTIOXIDANT DELIVERY CAT, SP1, GPX1 KDM4E 2947/4885XDH 1117/4885MAOA 1476/4885
US-20170266153-A1 COMPOSITIONS PURPOSEFULLY SELECTED COMPRISING PURIFIED CANNABINOIDS AND/OR PURIFIED TERPENES CNR2, CNR1, FAAH KDM4E 943/4885XDH 4711/4885MAOA 3650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.