Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | XDH | P47989 | 4/20 | 1.00 |
| ▸ | MAOA | P21397 | 3/20 | 1.00 |
| ▸ | EPHX2 | P34913 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | HES1 | Q14469 | 2/20 | 1.00 |
| ▸ | FANCF | Q9NPI8 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | KDM1A | O60341 | 1/20 | 1.00 |
| ▸ | PRSS1 | P07477 | 1/20 | 1.00 |
| ▸ | PRSS2 | P07478 | 1/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 1/20 | 1.00 |
| ▸ | HMGB1 | P09429 | 1/20 | 1.00 |
| ▸ | CFTR | P13569 | 1/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 1/20 | 1.00 |
| ▸ | ACHE | P22303 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | PRSS3 | P35030 | 1/20 | 1.00 |
| ▸ | BACE1 | P56817 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rutin SCHEMBL15263233 | 1.00 | KDM4E (1.00) | KDM4EXDHMAOAEPHX2MAPT | |
| Rutin SCHEMBL13696608 | 1.00 | KDM4E (1.00) | KDM4EXDHMAOAEPHX2MAPT | |
| Rutin SCHEMBL802819 | 1.00 | KDM4E (1.00) | KDM4EXDHMAOAEPHX2MAPT | |
| Rutin SCHEMBL20576343 | 1.00 | KDM4E (1.00) | KDM4EXDHMAOAEPHX2MAPT | |
| Rutin SCHEMBL13696392 | 1.00 | KDM4E (1.00) | KDM4EXDHMAOAEPHX2MAPT | |
| Rutin SCHEMBL21424757 | 1.00 | KDM4E (1.00) | KDM4EXDHMAOAEPHX2MAPT | |
| Rutin SCHEMBL23663918 | 1.00 | KDM4E (1.00) | KDM4EXDHMAOAEPHX2MAPT | |
| Rutin SCHEMBL21013017 | 1.00 | KDM4E (1.00) | KDM4EXDHMAOAEPHX2MAPT | |
| Rutin SCHEMBL21325433 | 1.00 | KDM4E (1.00) | KDM4EXDHMAOAEPHX2MAPT | |
| Rutin SCHEMBL21699244 | 1.00 | KDM4E (1.00) | KDM4EXDHMAOAEPHX2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11819511-B2 | Composition of N-palmitoyl-ethanolamide and Rutin in co-micronized form | EPITECH GROUP S.P.A. (IT) | 2023-11-21 | — | — | US | disclosed |
| US-20180064774-A1 | COMPOSITIONS FOR USE IN THE TREATMENT OF TUMORS RESISTANT TO CHEMOTHERAPY | PROBIOTICAL S.P.A. (IT) | 2018-03-08 | — | — | US | disclosed |
| US-9828407-B2 | Water soluble and activable phenolic derivatives with dermocosmetic and therapeutic applications and process for preparing said derivatives | LIBRAGEN (FR) | 2017-11-28 | — | — | US | disclosed |
| US-9757405-B2 | Compositions comprising rutin useful for the treatment of tumors resistant to chemotherapy | PROBIOTICAL S.P.A. (IT) | 2017-09-12 | — | — | US | disclosed |
| US-20170209416-A1 | COMPOSITIONS COMPRISING MELATONIN AND FLAVONOIDS FOR USE IN THE TREATMENT OF TUMOURS RESISTANT TO CHEMOTHERAPY | PROBIOTICAL S.P.A. (IT) | 2017-07-27 | — | — | US | disclosed |
| US-9707316-B2 | Crosslinked polymers including one or more antioxidants, methods for making same and methods for selecting antioxidants | ZIMMER, INC. (US) | 2017-07-18 | — | — | US | disclosed |
| US-20160250381-A1 | CROSSLINKED POLYMERS INCLUDING ONE OR MORE ANTIOXIDANTS, METHODS FOR MAKING SAME AND METHODS FOR SELECTING ANTIOXIDANTS | ZIMMER INC (US) | 2016-09-01 | — | — | US | disclosed |
| US-20160213698-A1 | COMPOSITIONS COMPRISING RUTIN USEFUL FOR THE TREATMENT OF TUMORS RESISTANT TO CHEMOTHERAPY | PROBIOTICAL S.P.A. (IT) | 2016-07-28 | — | — | US | disclosed |
| US-9370602-B2 | Crosslinked polymers including one or more antioxidants, methods for making same and methods for selecting antioxidants | ZIMMER, INC. (US) | 2016-06-21 | — | — | US | disclosed |
| US-9040489-B2 | Nanocrystalline photocatalytic colloid, a method of producing it and its use | JAGIELLONIAN UNIVERSITY (PL) | 2015-05-26 | — | — | US | disclosed |
| US-9012120-B2 | Production process of toner for electrostatic image development | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2015-04-21 | — | — | US | disclosed |
| US-20140088030-A1 | WATER SOLUBLE AND ACTIVABLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS AND PROCESS FOR PREPARING SAID DERIVATIVES | LIBRAGEN (FR) | 2014-03-27 | — | — | US | disclosed |
| US-20130122073-A1 | COMPOSITION IN THE FORM OF LIQUID FOR MAINTENANANCE OF CONTACT LENSES AND MEDICAL MATERIALS | UNIWERSYTET JAGIELLONSKI (PL) | 2013-05-16 | — | — | US | disclosed |
| US-20120071428-A1 | NANOCRYSTALLINE PHOTOCATALYTIC COLLOID, A METHOD OF PRODUCING IT AND ITS USE | JAGIELLONIAN UNIVERSITY (PL) | 2012-03-22 | — | — | US | disclosed |
| US-20110183930-A1 | WATER SOLUBLE AND ACTIVABLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS AND PROCESS FOR PREPARING SAID DERIVATIVES | LIBRAGEN (FR) | 2011-07-28 | — | — | US | disclosed |
| US-20080139664-A1 | ANTI-GLYCATION AGENTS FOR PREVENTING AGE-, DIABETES-, AND SMOKING-RELATED COMPLICATIONS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180064774-A1 | COMPOSITIONS FOR USE IN THE TREATMENT OF TUMORS RESISTANT TO CHEMOTHERAPY | SLC11A2, HES1, MTDH | KDM4E 3205/4885XDH 335/4885MAOA 2786/4885 |
| US-20080139664-A1 | ANTI-GLYCATION AGENTS FOR PREVENTING AGE-, DIABETES-, AND SMOKING-RELATED COMPLICATIONS | AGER, GID4, GALE | KDM4E 1615/4885XDH 1066/4885MAOA 197/4885 |
| US-11819511-B2 | Composition of N-palmitoyl-ethanolamide and Rutin in co-micronized form | EPN1, CNR2, NAPEPLD | KDM4E 4459/4885XDH 4555/4885MAOA 586/4885 |
| US-20120071428-A1 | NANOCRYSTALLINE PHOTOCATALYTIC COLLOID, A METHOD OF PRODUCING IT AND ITS USE | UROD, CRYZ, CRYAB | KDM4E 1774/4885XDH 4649/4885MAOA 1830/4885 |
| US-20110183930-A1 | WATER SOLUBLE AND ACTIVABLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS AND PROCESS FOR PREPARING SAID DERIVATIVES | UGGT1, TYR, G6PD | KDM4E 949/4885XDH 166/4885MAOA 688/4885 |
| US-20130122073-A1 | COMPOSITION IN THE FORM OF LIQUID FOR MAINTENANANCE OF CONTACT LENSES AND MEDICAL MATERIALS | MLEC, CRYZ, LAGE3 | KDM4E 2366/4885XDH 554/4885MAOA 1996/4885 |
| US-20140088030-A1 | WATER SOLUBLE AND ACTIVABLE PHENOLICS DERIVATIVES WITH DERMOCOSMETIC AND THERAPEUTIC APPLICATIONS AND PROCESS FOR PREPARING SAID DERIVATIVES | UGGT1, TYR, G6PD | KDM4E 949/4885XDH 166/4885MAOA 688/4885 |
| US-20160213698-A1 | COMPOSITIONS COMPRISING RUTIN USEFUL FOR THE TREATMENT OF TUMORS RESISTANT TO CHEMOTHERAPY | SLC11A2, ABCC1, VHL | KDM4E 4553/4885XDH 2493/4885MAOA 4250/4885 |
| US-20170209416-A1 | COMPOSITIONS COMPRISING MELATONIN AND FLAVONOIDS FOR USE IN THE TREATMENT OF TUMOURS RESISTANT TO CHEMOTHERAPY | MTNR1B, MTNR1A, EGLN2 | KDM4E 2691/4885XDH 655/4885MAOA 853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.