Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044175 | 0.89 | TSPO (0.43) | TSPOALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL8044214 | 0.89 | SMN1; SMN2 (0.39) | TSPOKMT2ASMN1; SMN2POLBACACB | |
| SCHEMBL8037870 | 0.86 | LTA4H (0.46) | TSPOKMT2ASMN1; SMN2TDP1TSHR | |
| SCHEMBL8037899 | 0.84 | MAPT (0.51) | TSPOALDH1A1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL8037882 | 0.84 | LTA4H (0.48) | TSPOSMN1; SMN2TSHRMAPTCYP3A4 | |
| SCHEMBL6405714 | 0.83 | ALOX5 (0.47) | TSPOALDH1A1SMN1; SMN2ACACBRAB9A | |
| SCHEMBL6403207 | 0.82 | TSPO (0.45) | TSPOALDH1A1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL8039723 | 0.81 | PNLIP (0.47) | TSPOALDH1A1KDM4EKMT2AACACB | |
| SCHEMBL8041192 | 0.80 | TSPO (0.41) | TSPOALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL8041220 | 0.78 | MTNR1A (0.41) | SMN1; SMN2POLBACACBACACAMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |