SCHEMBL8056764

SCHEMBL8056764

CC(C)(C)NCCOCCN

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.36
ALDH1A1 P00352 3/20 0.36
GAA P10253 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18792783 0.98 KDM4E (0.39) KDM4EALDH1A1MEN1KMT2A
SCHEMBL8063331 0.98 KDM4E (0.39) KDM4EALDH1A1MEN1KMT2A
SCHEMBL1368658 0.87 KDM4E (0.42) KDM4EALDH1A1GAAMEN1KMT2A
SCHEMBL22932152 0.86 ALDH1A1 (0.34) KDM4EALDH1A1MEN1KMT2A
SCHEMBL9541679 0.85 KDM4E (0.45) KDM4EALDH1A1GAAMEN1KMT2A
SCHEMBL14198320 0.85 KDM4E (0.45) KDM4EALDH1A1GAAMEN1KMT2A
SCHEMBL9540608 0.85 KDM4E (0.45) KDM4EALDH1A1GAAMEN1KMT2A
SCHEMBL19606314 0.85 KDM4E (0.33) KDM4EALDH1A1MEN1KMT2A
SCHEMBL22851377 0.85 POLB (0.38) KDM4EALDH1A1
SCHEMBL24246012 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180222847-A1 DIAMINE HAVING TERT-ALKYLAMINO GROUP AND PRIMARY AMINO GROUP FOR USE IN GAS SCRUBBING BASF SE (DE) 2018-08-09 US claimed
EP-3186222-B1 DIAMINE WITH TERTIARY ALKYL-AMINO AND PRIMARY AMINO GROUP FOR USE IN GAS SCRUBBING BASF SE (DE) 2018-06-06 EP claimed
EP-3186222-A1 DIAMINE HAVING TERT-ALKYLAMINO GROUP AND PRIMARY AMINO GROUP FOR USE IN GAS SCRUBBING BASF SE (DE) 2017-07-05 EP claimed
WO-2016030277-A1 DIAMINE HAVING TERT-ALKYLAMINO GROUP AND PRIMARY AMINO GROUP FOR USE IN GAS SCRUBBING BASF SE (DE) 2016-03-03 WO claimed
WO-2023118961-A1 ANTIBODY DRUG CONJUGATES COMPRISING TOXINS WITH POLAR GROUPS AND USES THEREOF INTOCELL, INC. (KR) 2023-06-29 WO disclosed
US-11584748-B2 Spirocyclic compounds C4 THERAPEUTICS, INC. (US) 2023-02-21 US disclosed
US-20230019060-A1 HETEROCYCLIC COMPOUNDS FOR MEDICAL TREATMENT C4 THERAPEUTICS, INC. (US) 2023-01-19 US disclosed
US-11242323-B2 Inhibition of OLIG2 activity Curtana Pharmaceuticals, Inc. (US) 2022-02-08 US disclosed
US-20210253535-A1 INHIBITION OF OLIG2 ACTIVITY Curtana Pharmaceuticals, Inc. 2021-08-19 US disclosed
US-20210032245-A1 SPIROCYCLIC COMPOUNDS C4 THERAPEUTICS, INC. (US) 2021-02-04 US disclosed
CN-106604771-B Diamines with tertiary alkylamino and primary amino groups for gas scrubbing 巴斯夫欧洲公司 2020-06-09 CN disclosed
CN-106604771-B Diamines with tertiary alkylamino and primary amino groups for gas scrubbing 巴斯夫欧洲公司 2020-06-09 CN disclosed
US-20080058636-A1 METHODS OF MYOCARDIAL IMAGING EPIX PHARMACEUTICALS, INC. 2008-03-06 US disclosed
US-20080044360-A1 METHODS OF COLLAGEN IMAGING EPIX PHARMACEUTICALS, INC. 2008-02-21 US disclosed
US-20070293656-A1 COLLAGEN BINDING PEPTIDES EPIX PHARMACEUTICALS, INC. 2007-12-20 US disclosed
US-20070185311-A1 Peptide-Based Multimeric Targeted Contrast Agents EPIX PHARMACEUTICALS, INC. (US) 2007-08-09 US disclosed
US-20070154948-A1 Novel antibacterial agents THERAVANCE BIOPHARMA ANTIBIOTICS IP, LLC 2007-07-05 US disclosed
US-7238341-B2 Peptide-based multimeric targeted contrast agents EPIX PHARMACEUTICALS, INC. (US) 2007-07-03 US disclosed
US-20060039861-A1 Peptide-based multimeric targeted contrast agents EPIX MEDICAL, INC., A DELAWARE CORPORATION 2006-02-23 US disclosed
US-20050074411-A1 Peptide-based multimeric targeted contrast agents EPIX MEDICAL, INC. A DELAWARE CORPORATION 2005-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060039861-A1 Peptide-based multimeric targeted contrast agents NGLY1, IAPP, NPPA KDM4E 4774/4885ALDH1A1 4848/4885GAA 2063/4885
US-20230019060-A1 HETEROCYCLIC COMPOUNDS FOR MEDICAL TREATMENT CRBN, MDM2, RBX1 KDM4E 1086/4885ALDH1A1 2742/4885GAA 1626/4885
US-20210253535-A1 INHIBITION OF OLIG2 ACTIVITY GLI2, ING2, GMFG KDM4E 2547/4885ALDH1A1 1478/4885GAA 2405/4885
US-20180222847-A1 DIAMINE HAVING TERT-ALKYLAMINO GROUP AND PRIMARY AMINO GROUP FOR USE IN GAS SCRUBBING TST, ALKBH1, CTH KDM4E 1030/4885ALDH1A1 583/4885GAA 4767/4885
US-20080058636-A1 METHODS OF MYOCARDIAL IMAGING FABP3, TNNI3, TNNT2 KDM4E 4464/4885ALDH1A1 4515/4885GAA 3486/4885
US-20070185311-A1 Peptide-Based Multimeric Targeted Contrast Agents NGLY1, IAPP, NPPA KDM4E 4774/4885ALDH1A1 4848/4885GAA 2063/4885
US-20080044360-A1 METHODS OF COLLAGEN IMAGING COL14A1, COL2A1, COL1A1 KDM4E 4372/4885ALDH1A1 4592/4885GAA 3768/4885
US-20050074411-A1 Peptide-based multimeric targeted contrast agents NGLY1, IAPP, NPPA KDM4E 4774/4885ALDH1A1 4848/4885GAA 2063/4885
US-20210032245-A1 SPIROCYCLIC COMPOUNDS CRBN, RBX1, XIAP KDM4E 1861/4885ALDH1A1 2000/4885GAA 2719/4885
US-20070293656-A1 COLLAGEN BINDING PEPTIDES COL14A1, COL2A1, COL1A1 KDM4E 4176/4885ALDH1A1 4339/4885GAA 2574/4885
US-11242323-B2 Inhibition of OLIG2 activity POU2F2, ING2, PAX2 KDM4E 2188/4885ALDH1A1 1801/4885GAA 2429/4885
US-11584748-B2 Spirocyclic compounds CRBN, RBX1, XIAP KDM4E 1861/4885ALDH1A1 2000/4885GAA 2719/4885
US-20070154948-A1 Novel antibacterial agents ENGASE, PGLS, PEPD KDM4E 2410/4885ALDH1A1 2244/4885GAA 25/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.