SCHEMBL81163

SCHEMBL81163

C=C(C)C(=O)OC[Si](C)(C)OCC

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.48
TSHR P16473 4/20 0.43
ALDH1A1 P00352 6/20 0.42
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
GLO1 Q04760 1/20 0.31
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL237187 0.85 TSHR (0.49) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL143881 0.85 THRB (0.48) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL80190 0.82 THRB (0.50) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL332509 0.82 TSHR (0.47) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL7190871 0.82 TSHR (0.47) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16537817 0.81 THRB (0.46) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL340146 0.81 THRB (0.55) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL231313 0.80 ALDH1A1 (0.42) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL229519 0.80 TSHR (0.45) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL28561857 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 845 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260049202-A1 SILANE COMPOUND AND COMPOSITIONS CONTAINING SAME SYNTHOMER SDN BHD (MY) 2026-02-19 US claimed
EP-4619470-A1 SILANE COMPOUND AND COMPOSITIONS CONTAINING SAME Synthomer Sdn. Bhd. (MY) 2025-09-24 EP claimed
US-12358933-B2 Meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method PIOCEL CO., LTD. (KR) 2025-07-15 US claimed
CN-120202247-A Silane compound and composition containing same 昕特玛私人有限公司 2025-06-24 CN claimed
US-20250109153-A1 A novel meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method PIOCEL CO., LTD. (KR) 2025-04-03 US claimed
WO-2024107042-A1 SILANE COMPOUND AND COMPOSITIONS CONTAINING SAME SYNTHOMER SDN BHD (MY) 2024-05-23 WO claimed
US-11975125-B2 Medical devices MICROVENTION, INC. (US) 2024-05-07 US claimed
EP-3860669-B1 MEDICAL DEVICES MICROVENTION INC (US) 2024-04-03 EP claimed
US-20240093058-A1 POLYSILAZANE HARD COATING COMPOSITIONS MERCK PATENT GMBH (DE) 2024-03-21 US claimed
EP-4274866-A1 POLYSILAZANE HARD COATING COMPOSITIONS Merck Patent GmbH (DE) 2023-11-15 EP claimed
WO-2005124792-A1 ANTI-CORROSION ADDITIVE FOR ELECTRICAL CABLE RESTORATION FLUIDS DOW CORNING CORPORATION (US) 2005-12-29 WO claimed
US-6841694-B2 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-01-11 US claimed
EP-1469002-A1 Method for stabilizing unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2004-10-20 EP claimed
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds WACKER-CHEMIE GMBH (DE) 2004-09-02 US claimed
US-6699935-B2 A CROSSLINKED RUBBER PARTICLES CONTAINING CONJUGATED DIENE MONOMER, AROMATIC VINYL MONOMER AND MONOMER WITH AT LEAST TWO POLYMERIZABLE UNSATURATED GROUPS DISPERSED IN A CONJUGATED DIENE/AROMATIC VINYL COPOLYMER; RESIST TO ROLLING, SKID, WEAR JSR CORPORATION (JP) 2004-03-02 US claimed
US-6653404-B2 Melt processability; dimensional stability JSR CORPORATION (JP) 2003-11-25 US claimed
US-20030125467-A1 A crosslinked rubber particles containing conjugated diene monomer, aromatic vinyl monomer and monomer with at least two polymerizable unsaturated groups dispersed in a conjugated diene/aromatic vinyl copolymer; resist to rolling, skid, wear JSR CORPORATION (JP) 2003-07-03 US claimed
EP-1298166-A1 RUBBER COMPOSITION JSR Corporation (JP) 2003-04-02 EP claimed
US-20010053813-A1 Rubber compositions JSR CORPORATION (JP) 2001-12-20 US claimed
US-6136874-A Microporous polymeric foams made with silicon or germanium based monomers THE PROCTER & GAMBLE COMPANY (US) 2000-10-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12358933-B2 Meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method SPEN, SAE1, OSTC THRB 3131/4885TSHR 3556/4885ALDH1A1 4639/4885
US-20040171859-A1 Process for stabilizing unsaturated organosilicon compounds ELOVL1, ELOVL6, DEGS1 THRB 4533/4885TSHR 4650/4885ALDH1A1 402/4885
US-20260049202-A1 SILANE COMPOUND AND COMPOSITIONS CONTAINING SAME ALG3, SNW1, SMURF1 THRB 4034/4885TSHR 4518/4885ALDH1A1 2065/4885
US-20250109153-A1 A novel meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method SPEN, SAE1, SOST THRB 3126/4885TSHR 3789/4885ALDH1A1 4652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.