Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5059015 | 0.90 | GRM4 (0.42) | GRM4ALDH1A1 | |
| SCHEMBL1747420 | 0.83 | — | — | |
| SCHEMBL12161161 | 0.79 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL41615 | 0.79 | TGFBR1 (0.32) | — | |
| SCHEMBL150441 | 0.77 | ALDH1A1 (0.43) | LPAR3ALDH1A1 | |
| SCHEMBL2552708 | 0.77 | MEN1 (0.46) | GRM4TYMSLPAR3LPAR2ALDH1A1 | |
| SCHEMBL29062417 | 0.76 | FNTA (0.34) | GRM4TYMSLPAR3LPAR2S1PR2 | |
| SCHEMBL9320159 | 0.75 | PAOX (0.34) | ALDH1A1 | |
| SCHEMBL20497399 | 0.75 | GRM4 (0.37) | GRM4TYMSLPAR3LPAR2ALDH1A1 | |
| SCHEMBL6232119 | 0.74 | ALDH1A1 (0.52) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108348402-B | Polymerizable composition based on thermally cleavable compounds | 义获嘉伟瓦登特公司 | 2021-02-02 | — | — | CN | claimed |
| EP-2578201-B1 | Dental materials with improved hydrolysis stability on the basis of phthalic acid monomers | IVOCLAR VIVADENT AG (LI) | 2020-11-25 | — | — | EP | claimed |
| US-10667993-B2 | Polymerizable compositions based on thermally cleavable compounds | IVOCLAR VIVADENT AG (LI) | 2020-06-02 | — | — | US | claimed |
| EP-3156031-B9 | POLYMERISABLE COMPOSITIONS BASED ON THERMALLY CLEAVABLE COMPOUNDS | IVOCLAR VIVADENT AG (LI) | 2020-03-18 | — | — | EP | claimed |
| EP-3156031-B1 | POLYMERISABLE COMPOSITIONS BASED ON THERMALLY CLEAVABLE COMPOUNDS | IVOCLAR VIVADENT AG (LI) | 2019-08-28 | — | — | EP | claimed |
| EP-2753291-B1 | DENTAL MATERIALS BASED ON COMPOUNDS HAVING DEBONDING-ON-DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2019-06-19 | — | — | EP | claimed |
| EP-2753290-B1 | DENTAL MATERIALS ON THE BASIS OF MONOMERS WITH DEBONDING ON DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2019-06-12 | — | — | EP | claimed |
| EP-2755624-B1 | DENTAL MATERIAL BASED ON STRONGLY ACIDIC POLYMERISABLE BISPHOSPHONIC ACIDS | IVOCLAR VIVADENT AG (LI) | 2018-11-14 | — | — | EP | claimed |
| US-20180200155-A1 | Polymerizable Compositions Based On Thermally Cleavable Compounds | IVOCLAR VIVADENT AG (LI) | 2018-07-19 | — | — | US | claimed |
| US-9668946-B2 | Dental materials based on monomers having debonding-on-demand properties | IVOCLAR VIVADENT AG (LI) | 2017-06-06 | — | — | US | claimed |
| WO-2013083734-A1 | DENTAL MATERIALS ON THE BASIS OF HIGHLY ACIDIC POLYMERISABLE BISPHOSPHONIC ACIDS | IVOCLAR VIVADENT AG (LI) | 2013-06-13 | — | — | WO | claimed |
| US-20130123147-A1 | POLYMERS HAVING ACID AND AMIDE MOIETIES, AND USES THEREOF | ISP INVESTMENTS INC. (US) | 2013-05-16 | — | — | US | claimed |
| US-20130090404-A1 | Dental materials with improved hydrolysis stability based on phthalic acid monomers | IVOCLAR VIVADENT AG (LI) | 2013-04-11 | — | — | US | claimed |
| EP-2578201-A1 | Dental materials with improved hydrolysis stability on the basis of phthalic acid monomers | Ivoclar Vivadent AG (LI) | 2013-04-10 | — | — | EP | claimed |
| WO-2013034777-A2 | DENTAL MATERIALS BASED ON MONOMERS HAVING DEBONDING-ON-DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2013-03-14 | — | — | WO | claimed |
| WO-2013034778-A2 | DENTAL MATERIALS BASED ON COMPOUNDS HAVING DEBONDING-ON-DEMAND PROPERTIES | IVOCLAR VIVADENT AG (LI) | 2013-03-14 | — | — | WO | claimed |
| WO-2011130370-A1 | POLYMERS HAVING ACID AND AMIDE MOIETIES, AND USES THEREOF | ISP INVESTMENTS INC. (US) | 2011-10-20 | — | — | WO | claimed |
| US-7714034-B2 | Photopolymerizable dental materials with bisacylphosphine oxides as initiators | IVOCLAR VIVADENT AG (LI) | 2010-05-11 | — | — | US | claimed |
| EP-1749513-B1 | Photopolymerisable dental material with bisacylphosphine oxides as initiator | IVOCLAR VIVADENT AG (LI) | 2009-03-04 | — | — | EP | claimed |
| US-20070027229-A1 | Photopolymerizable dental materials with bisacylphosphine oxides as initiators | IVOCLAR VIVADENT AG (LI) | 2007-02-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180200155-A1 | Polymerizable Compositions Based On Thermally Cleavable Compounds | CAD, TERB1, MLX | GRM4 2193/4885TYMS 310/4885LPAR3 4648/4885 |
| US-10667993-B2 | Polymerizable compositions based on thermally cleavable compounds | CAD, TERB1, MLX | GRM4 2193/4885TYMS 310/4885LPAR3 4648/4885 |
| US-20130090404-A1 | Dental materials with improved hydrolysis stability based on phthalic acid monomers | RCOR1, SMC4, RER1 | GRM4 291/4885TYMS 4262/4885LPAR3 2130/4885 |
| US-20070027229-A1 | Photopolymerizable dental materials with bisacylphosphine oxides as initiators | PRXL2A, PGM2, PAM | GRM4 791/4885TYMS 2698/4885LPAR3 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.