SCHEMBL818344

SCHEMBL818344

Cc1ccc(OC2CCCCO2)cc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TNK2 Q07912 3/20 0.40
HSD11B1 P28845 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
DHFR P00374 1/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
KDM4E B2RXH2 1/20 0.37
KDM4C Q9H3R0 1/20 0.36
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPY1R P25929 1/20 0.35
NPY2R P49146 1/20 0.35
NPY4R P50391 1/20 0.35
NPY5R Q15761 1/20 0.35
MAOB P27338 1/20 0.35
ACHE P22303 1/20 0.34
SLC18A3 Q16572 1/20 0.34
PDE4B Q07343 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3500438 0.91 TNK2 (0.44) TNK2HSD11B1MEN1KMT2ADHFR
SCHEMBL11892016 0.89 ACHE (0.39) MEN1KMT2ANPC1RAB9AKDM4E
SCHEMBL21780925 0.88 MEN1 (0.47) HSD11B1MEN1KMT2ANPC1RAB9A
SCHEMBL813805 0.86 NPC1 (0.46) TNK2HSD11B1MEN1KMT2ADHFR
SCHEMBL23677866 0.83 TNK2 (0.41) TNK2HSD11B1MEN1KMT2ADHFR
SCHEMBL7231933 0.83 NPY1R (0.54) TNK2HSD11B1MEN1KMT2ADHFR
SCHEMBL4382295 0.83 MEN1 (0.45) TNK2HSD11B1MEN1KMT2ADHFR
SCHEMBL1457107 0.83 NPY1R (0.43) TNK2HSD11B1MEN1KMT2ADHFR
SCHEMBL5708685 0.82 MEN1 (0.44) TNK2HSD11B1MEN1KMT2ADHFR
SCHEMBL5535757 0.82 TNK2 (0.40) TNK2HSD11B1MEN1KMT2ADHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018145219-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ADDICTIONS BY MEANS OF AVERSIVE COUNTERCONDITIONING SERANI MOSTAZAL JORGE (CL) 2018-08-16 WO claimed
US-20230157996-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF Shenzhen Bay Laboratory (CN) 2023-05-25 US disclosed
US-20230157996-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF Shenzhen Bay Laboratory (CN) 2023-05-25 US disclosed
WO-2022210901-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM 日産化学株式会社 2022-10-06 WO disclosed
EP-3892618-A1 4-PYRIDINYL FORMAMIDE COMPOUND OR DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) 2021-10-13 EP disclosed
US-10376479-B2 Endoxifen compositions and methods JINA PHARMACEUTICALS, INC. (US) 2019-08-13 US disclosed
US-20190231687-A1 ENDOXIFEN METHODS AND COMPOSITIONS IN THE TREATMENT OF PSYCHIATRIC AND NEURODEGENERATIVE DISEASES JINA PHARMACEUTICALS, INC. 2019-08-01 US disclosed
US-10252967-B2 Bridged bi-aromatic ligands and transition metal compounds prepared therefrom UNIVATION TECHNOLOGIES, LLC (US) 2019-04-09 US disclosed
EP-3286202-B1 BRIDGED BI-AROMATIC LIGANDS AND TRANSITION METAL COMPOUNDS PREPARED THEREFROM UNIVATION TECH LLC (US) 2019-03-13 EP disclosed
US-20180086685-A1 BRIDGED BI-AROMATIC LIGANDS AND TRANSITION METAL COMPOUNDS PREPARED THEREFROM UNIVATION TECHNOLOGIES, LLC (US) 2018-03-29 US disclosed
US-20090105474-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2009-04-23 US disclosed
WO-2008070463-A9 ENDOXIFEN METHODS AND COMPOSITIONS JINA PHARMACEUTICALS INC (US) 2008-09-18 WO disclosed
WO-2008070463-A2 ENDOXIFEN METHODS AND COMPOSITIONS JINA PHARMACEUTICALS, INC. (US) 2008-06-12 WO disclosed
EP-1860098-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-11-28 EP disclosed
CN-100343232-C Bisimide compound, acid generator and resist composition using the same, and pattern forming method using the composition WAKO PURE CHEM IND LTD (JP) 2007-10-17 CN disclosed
CN-1592738-A Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEM IND LTD (JP) 2005-03-09 CN disclosed
US-6541490-B1 Treating ischemia or reoxygenation injury; preparation from a bipyridine, a benzeneboronic acid and a manganese salt EUKARION, INC. 2003-04-01 US disclosed
EP-1119573-A2 BIPYRIDINE MANGANESE COMPLEXES EUKARION, INC. (US) 2001-08-01 EP disclosed
US-6177419-B1 ANTIOXIDANT CHELATE COMPOUNDS FOR PREVENTING OXYGEN FREE RADICAL-ASSOCIATED DISEASES IN MAMMALS; NEUROPROTECTANTS, SUPEROXIDE DISMUTASE (SOD), CATALASE (CAT) AND/OR PEROXIDASE (POD) MIMETICS EUKARION, INC. 2001-01-23 US disclosed
WO-2000009512-A2 BIPYRIDINE MANGANESE COMPLEXES EUKARION, INC. (US) 2000-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157996-A1 SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF SSB, EBNA1BP2, PML TNK2 2672/4885HSD11B1 3709/4885MEN1 763/4885
US-10376479-B2 Endoxifen compositions and methods CYP46A1, PLA2G2F, VDR TNK2 1702/4885HSD11B1 625/4885MEN1 1461/4885
US-20190231687-A1 ENDOXIFEN METHODS AND COMPOSITIONS IN THE TREATMENT OF PSYCHIATRIC AND NEURODEGENERATIVE DISEASES NLN, BDNF, LITAF TNK2 2698/4885HSD11B1 1963/4885MEN1 3386/4885
US-20180086685-A1 BRIDGED BI-AROMATIC LIGANDS AND TRANSITION METAL COMPOUNDS PREPARED THEREFROM WEE2, WEE1, AHR TNK2 2218/4885HSD11B1 4517/4885MEN1 4617/4885
US-10252967-B2 Bridged bi-aromatic ligands and transition metal compounds prepared therefrom WEE2, WEE1, AHR TNK2 2218/4885HSD11B1 4517/4885MEN1 4617/4885
US-20090105474-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF MMP13, MMP11, MMP3 TNK2 1246/4885HSD11B1 767/4885MEN1 2810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.