SCHEMBL825694

SCHEMBL825694

O=CCCC1=CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
ALOX15 P16050 2/20 0.47
TAAR1 Q96RJ0 1/20 0.45
USP2 O75604 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
SMN1; SMN2 Q16637 5/20 0.41
NPC1 O15118 4/20 0.40
RAB9A P51151 4/20 0.40
HPGD P15428 2/20 0.40
LMNA P02545 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MAPT P10636 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5918013 0.98 ALDH1A1 (0.46) ALDH1A1ALOX15TAAR1USP2NPSR1
SCHEMBL5918020 0.98 ALDH1A1 (0.46) ALDH1A1ALOX15TAAR1USP2NPSR1
SCHEMBL5918017 0.98 ALDH1A1 (0.46) ALDH1A1ALOX15TAAR1USP2NPSR1
SCHEMBL826064 0.88 ALDH1A1 (0.45) ALDH1A1ALOX15TAAR1USP2NPSR1
SCHEMBL6590309 0.79 ALDH1A1 (0.43) ALDH1A1ALOX15TAAR1USP2NPSR1
SCHEMBL861710 0.79 ALDH1A1 (0.43) ALDH1A1ALOX15TAAR1USP2NPSR1
SCHEMBL3943711 0.79 ALDH1A1 (0.43) ALDH1A1ALOX15TAAR1USP2NPSR1
SCHEMBL8118694 0.79 ALDH1A1 (0.47) ALDH1A1ALOX15TAAR1USP2NPSR1
SCHEMBL4395085 0.79 ALDH1A1 (0.56) ALDH1A1ALOX15TAAR1SMN1; SMN2NPC1
SCHEMBL826103 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12234253-B2 Silicone compounds with a substituted amine group and a benefit agent moiety THE PROCTER & GAMBLE COMPANY (US) 2025-02-25 US claimed
US-20250051370-A1 SILICONE COMPOUNDS PROCTER & GAMBLE (US) 2025-02-13 US claimed
US-20220064191-A1 SILICONE COMPOUNDS PROCTER & GAMBLE (US) 2022-03-03 US claimed
EP-3649184-A1 SILICONE COMPOUNDS The Procter and Gamble Company (US) 2020-05-13 EP claimed
EP-3649183-A1 SILICONE COMPOUNDS The Procter and Gamble Company (US) 2020-05-13 EP claimed
US-10336966-B2 Fragrance compositions and uses thereof THE PROCTER & GAMBLE COMPANY (US) 2019-07-02 US claimed
US-20190010293-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY 2019-01-10 US claimed
US-20190010427-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY 2019-01-10 US claimed
WO-2019010263-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2019-01-10 WO claimed
WO-2019010265-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2019-01-10 WO claimed
EP-2961374-B1 FRAGRANCE COMPOSITIONS PROCTER & GAMBLE (US) 2017-01-25 EP claimed
US-20160137674-A1 SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY 2016-05-19 US claimed
EP-2961374-A1 FRAGRANCE COMPOSITIONS The Procter & Gamble Company (US) 2016-01-06 EP claimed
WO-2015089246-A1 FRAGRANCE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2015-06-18 WO claimed
US-20150164764-A1 Fragrance Compositions THE PROCTER & GAMBLE COMPANY 2015-06-18 US claimed
EP-2046147-B1 METHOD OF USING ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2013-05-01 EP claimed
US-20090311403-A1 Method of Using Organic Compounds GIVAUDAN SA (CH) 2009-12-17 US claimed
CN-101494999-A Method for using organic compound GIVAUDAN SA (CH) 2009-07-29 CN claimed
EP-2046147-A1 METHOD OF USING ORGANIC COMPOUNDS Givaudan SA (CH) 2009-04-15 EP claimed
WO-2008011742-A1 METHOD OF USING ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2008-01-31 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160137674-A1 SILICONE COMPOUNDS SMCHD1, SRI, SMS ALDH1A1 3917/4885ALOX15 2271/4885TAAR1 1199/4885
US-20250051370-A1 SILICONE COMPOUNDS SMCHD1, SRI, SMS ALDH1A1 3917/4885ALOX15 2271/4885TAAR1 1199/4885
US-20090311403-A1 Method of Using Organic Compounds MGLL, GK, LIPC ALDH1A1 788/4885ALOX15 448/4885TAAR1 890/4885
US-20150164764-A1 Fragrance Compositions OGG1, ALKBH5, MYB ALDH1A1 1367/4885ALOX15 138/4885TAAR1 2729/4885
US-12234253-B2 Silicone compounds with a substituted amine group and a benefit agent moiety SMS, SRM, AAAS ALDH1A1 3361/4885ALOX15 2826/4885TAAR1 59/4885
US-10336966-B2 Fragrance compositions and uses thereof CUTA, DPM1, PLIN5 ALDH1A1 1263/4885ALOX15 33/4885TAAR1 1032/4885
US-20220064191-A1 SILICONE COMPOUNDS SMCHD1, SRI, SMS ALDH1A1 3917/4885ALOX15 2271/4885TAAR1 1199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.