Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8817028 | 0.81 | TDP1 (0.33) | KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL3435871 | 0.66 | FAAH (0.36) | KDM4EMAPTALOX15SMN1; SMN2 | |
| Bicine SCHEMBL783494 | 0.65 | KDM4E (0.91) | KDM4EMAPTALOX15SMN1; SMN2CA4 | |
| SCHEMBL382697 | 0.65 | ALOX15 (0.91) | KDM4EMAPTALOX15SMN1; SMN2CA4 | |
| SCHEMBL27712183 | 0.64 | SMN1; SMN2 (0.35) | KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL31349875 | 0.63 | KDM4E (0.95) | KDM4EMAPTALOX15SMN1; SMN2CA4 | |
| Water SCHEMBL11884555 | 0.63 | ALOX15 (0.86) | KDM4EMAPTALOX15SMN1; SMN2CA4 | |
| SCHEMBL1551330 | 0.63 | TDP1 (0.33) | KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL379765 | 0.62 | ALOX15 (1.00) | KDM4EMAPTALOX15SMN1; SMN2CA4 | |
| SCHEMBL15992394 | 0.62 | KDM4E (0.45) | KDM4EMAPTALOX15SMN1; SMN2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060121-A | Microcontact printing of catalytic colloids | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2000-05-09 | — | — | US | disclosed |
| US-5925463-A | METALS OF GROUPS 1B,2B,3,4,5,6,7B,8, LANTHANOIDES, AND/OR ACTINOIDES ARE CATHODICALLY REDUCED IN THE PRESENCE OF A STABILIZER, IN ORGANIC SOLVENTS TO FORM METAL COLLOID POWDERS OF CONTROLLED PARTICLE SIZES AND USE IN MAKING CATALYSTS | STUDIENGESELLSCHAFT KOHLE MBH | 1999-07-20 | — | — | US | disclosed |
| EP-0672765-B1 | Electrochemical reduction of metal salts as a method of preparing highly dispersed metal colloids and substrate fixed metal clusters by electrochemical reduction of metal salts | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1999-06-30 | — | — | EP | disclosed |
| US-5620584-A | Electrochemical reduction of metal salts as a method of preparing highly dispersed metal colloids and substrate fixed metal clusters by electrochemical reduction of metal salts | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1997-04-15 | — | — | US | disclosed |
| EP-0672765-A1 | Electrochemical reduction of metal salts as a method of preparing highly dispersed metal colloids and substrate fixed metal clusters by electrochemical reduction of metal salts | Studiengesellschaft Kohle mbH (DE) | 1995-09-20 | — | — | EP | disclosed |