Sugi Predict

Sugi Predict / Compounds / SCHEMBL830527

SCHEMBL830527

SCHEMBL830527

COCCCCCC(=O)Nc1ccc(OCC(=O)OC(=O)OC)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.53
▸ HDAC8 Q9BY41 5/20 0.51
▸ HDAC3 O15379 3/20 0.51
▸ HDAC4 P56524 3/20 0.51
▸ HDAC1 Q13547 3/20 0.51
▸ HDAC7 Q8WUI4 3/20 0.51
▸ HDAC2 Q92769 3/20 0.51
▸ HDAC10 Q969S8 3/20 0.51
▸ HDAC11 Q96DB2 3/20 0.51
▸ HDAC6 Q9UBN7 3/20 0.51
▸ HDAC9 Q9UKV0 3/20 0.51
▸ HDAC5 Q9UQL6 3/20 0.51
▸ GAA P10253 1/20 0.50
▸ HTT P42858 2/20 0.48
▸ ALDH1A1 P00352 4/20 0.46
▸ MAPT P10636 3/20 0.46
▸ MEN1 O00255 3/20 0.46
▸ KMT2A Q03164 3/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ NPC1 O15118 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL830198 0.83 ALDH1A1 (0.59) L3MBTL1HTTALDH1A1MAPTMEN1
SCHEMBL832151 0.79 TP53 (0.52) L3MBTL1GAAHTTALDH1A1MAPT
SCHEMBL831028 0.79 L3MBTL1 (0.60) L3MBTL1HDAC8HDAC3HDAC4HDAC1
SCHEMBL832133 0.75 HDAC8 (0.65) L3MBTL1HDAC8HDAC3HDAC4HDAC1
SCHEMBL831518 0.75 LTA4H (0.57) L3MBTL1HDAC8GAAALDH1A1MAPT
SCHEMBL830526 0.75 HDAC8 (0.55) L3MBTL1HDAC8HDAC3HDAC4HDAC1
SCHEMBL27291378 0.73 L3MBTL1 (0.96) L3MBTL1HDAC8HDAC3HDAC4HDAC1
SCHEMBL832065 0.72 LTA4H (0.53) L3MBTL1HDAC8GAAALDH1A1MAPT
SCHEMBL831684 0.72 HDAC8 (0.60) L3MBTL1HDAC8HDAC3HDAC4HDAC1
SCHEMBL831386 0.71 JAK2 (0.67) HDAC8HDAC1HDAC6HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE45548-E1 Functionalized drugs and polymers derived therefrom BEZWADA BIOMEDICAL, LLC (US) 2015-06-09 — — US disclosed
US-8846845-B2 Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices BEZWADA BIOMEDICAL, LLC (US) 2014-09-30 — — US disclosed
EP-2298235-B1 Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices BEZWADA BIOMEDICAL LLC (US) 2013-11-06 — — EP disclosed
US-8409559-B2 Functionalized drugs and polymers derived therefrom Bezwada Biomedical, Inc. (US) 2013-04-02 — — US disclosed
US-20120158127-A1 BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES BEZWADA BIOMEDICAL, LLC (US) 2012-06-21 — — US disclosed
US-8143325-B2 Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices BEZWADA BIOMEDICAL, LLC (US) 2012-03-27 — — US disclosed
EP-2298235-A1 Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices Bezwada Biomedical LLC (US) 2011-03-23 — — EP disclosed
US-20100260702-A1 BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES BEZWADA BIOMEDICAL LLC (US) 2010-10-14 — — US disclosed
US-7772352-B2 Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices BEZWADA BIOMEDICAL LLC (US) 2010-08-10 — — US disclosed
US-20100152272-A1 FUNCTIONALIZED DRUGS AND POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2010-06-17 — — US disclosed
US-7691364-B2 Functionalized drugs and polymers derived therefrom BEZWADA BIOMEDICAL, LLC (US) 2010-04-06 — — US disclosed
EP-1937182-A4 BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES BEZWADA BIOMEDICAL LLC (US) 2009-07-15 — — EP disclosed
EP-1937182-A2 BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES Bezwada Biomedical LLC (US) 2008-07-02 — — EP disclosed
EP-1931334-A2 FUNCTIONALIZED DRUGS AND POLYMERS DERIVED THEREFROM Bezwada Biomedical LLC (US) 2008-06-18 — — EP disclosed
WO-2007030538-A2 FUNCTIONALIZED DRUGS AND POLYMERS DERIVED THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-03-15 — — WO disclosed
WO-2007030464-A2 BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES BEZWADA BIOMEDICAL LLC (US) 2007-03-15 — — WO disclosed
US-20060188547-A1 Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices BEZWADA BIOMEDICAL, LLC (US) 2006-08-24 — — US disclosed
US-20060172983-A1 Functionalized drugs and polymers derived therefrom BEZWADA BIOMEDICAL, LLC (US) 2006-08-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152272-A1 FUNCTIONALIZED DRUGS AND POLYMERS THEREFROM OGFR, LOX, DDO L3MBTL1 1729/4885HDAC8 1077/4885HDAC3 366/4885
US-20120158127-A1 BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES HAO2, AOC2, AOC1 L3MBTL1 540/4885HDAC8 382/4885HDAC3 211/4885
US-20100260702-A1 BIOABSORBABLE AND BIOCOMPATIBLE POLYURETHANES AND POLYAMIDES FOR MEDICAL DEVICES ALOX12, HAO2, ALOX15 L3MBTL1 823/4885HDAC8 428/4885HDAC3 309/4885
US-20060172983-A1 Functionalized drugs and polymers derived therefrom OGFR, LOX, OPRM1 L3MBTL1 1631/4885HDAC8 1124/4885HDAC3 237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.