Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322075 | 0.88 | RXRA (0.46) | HPGDSALDH1A1CYP3A4ACACBACACA | |
| SCHEMBL8322073 | 0.81 | HPGDS (0.48) | PTGS2HPGDSALDH1A1CYP3A4ACACB | |
| SCHEMBL8313475 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TDP1KMT2AMAPTNPSR1 | |
| SCHEMBL10876301 | 0.78 | ALOX5 (0.68) | ALOX5PTGS1PTGS2 | |
| SCHEMBL8320373 | 0.75 | HDAC1 (0.57) | ALDH1A1TDP1KMT2AMAPTNPSR1 | |
| SCHEMBL8321150 | 0.74 | MGLL (0.39) | ALDH1A1CYP3A4TDP1HPGDMAPT | |
| SCHEMBL9877155 | 0.74 | HDAC2 (0.57) | ALOX5PTGS1PTGS2 | |
| SCHEMBL8321148 | 0.72 | RXRA (0.44) | ALDH1A1KMT2AHTTNPSR1HDAC1 | |
| SCHEMBL8317750 | 0.72 | ALDH1A1 (0.59) | ALDH1A1ACACBACACAKMT2AMAPT | |
| SCHEMBL8314172 | 0.72 | LMNA (0.47) | ALOX5ALDH1A1CYP3A4TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |