Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.46 |
| ▸ | ITGAV | P06756 | 18/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323234 | 0.82 | KLK7 (0.36) | ITGB3ITGA2B | |
| SCHEMBL8468002 | 0.82 | DHODH (0.37) | ITGB3ITGAVITGA2B | |
| SCHEMBL8328325 | 0.81 | ITGB3 (0.40) | ITGB3ITGAVITGA2B | |
| SCHEMBL8467842 | 0.77 | ITGB3 (0.72) | ITGB3ITGAVITGA2B | |
| SCHEMBL8467659 | 0.75 | GABRG2 (0.39) | ITGB3ITGAVITGA2B | |
| SCHEMBL7361297 | 0.75 | ITGB3 (0.54) | ITGB3ITGAVITGA2B | |
| SCHEMBL7366878 | 0.74 | ITGB3 (0.38) | ITGB3ITGAVITGA2B | |
| SCHEMBL7360585 | 0.70 | ITGB3 (0.72) | ITGB3ITGAVITGA2B | |
| SCHEMBL8467321 | 0.69 | GABRA1 (0.35) | — | |
| SCHEMBL5486017 | 0.67 | ITGB3 (0.65) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |