Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.41 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364492 | 0.88 | CTSD (0.48) | CTSDCASP3CASP7MAOB | |
| SCHEMBL7416124 | 0.83 | CASP3 (0.49) | CTSDCASP3CASP7 | |
| SCHEMBL9579040 | 0.82 | CASP3 (0.46) | CTSDCASP3CASP7 | |
| SCHEMBL7423864 | 0.80 | REN (0.45) | CTSDCASP3CASP7MAOBITGB3 | |
| SCHEMBL7418157 | 0.80 | REN (0.45) | CTSDCASP3CASP7ITGB3ITGA2B | |
| SCHEMBL8736216 | 0.80 | CTSD (0.53) | CTSDITGB3ITGA2B | |
| SCHEMBL7416869 | 0.79 | MME (0.43) | CTSDCASP3CASP7ITGB3ITGA2B | |
| SCHEMBL8366184 | 0.79 | CTSD (0.43) | CTSDCASP3CASP7 | |
| SCHEMBL8366182 | 0.79 | CTSD (0.43) | CTSDCASP3CASP7 | |
| SCHEMBL7420320 | 0.77 | REN (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717731-B1 | DIFLUORO STATONE ANTIVIRAL ANALOGS | MERRELL PHARMA INC (US) | 1999-04-21 | — | — | EP | claimed |