SCHEMBL851966

SCHEMBL851966

[CH2]C(CCCOC)CCOC

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7461191 0.84 ALDH1A1 (0.30) ALDH1A1
SCHEMBL10493641 0.79
SCHEMBL7462125 0.78
SCHEMBL7623165 0.76
SCHEMBL10482473 0.76
SCHEMBL10780011 0.74
SCHEMBL8994496 0.74
SCHEMBL28918664 0.74
SCHEMBL21066951 0.72 ALDH1A1 (0.32) ALDH1A1
SCHEMBL27882980 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3280402-B1 TOLAN COMPOUNDS FOR PROMOTING WOUND HEALING BIOMENDICS LLC (US) 2024-06-05 EP disclosed
CN-107847466-B Formulations and methods for modulating wound healing 贝欧曼蒂克丝公司 2024-02-06 CN disclosed
US-11786481-B2 Formulation and process for modulating wound healing BioMendics, LLC (US) 2023-10-17 US disclosed
US-20230130617-A1 PROCESS FOR IMPROVED OPIOID SYNTHESIS RHODES TECHNOLOGIES (US) 2023-04-27 US disclosed
US-20220296538-A1 Substituted Tolans for the Modulation of Microbial Colonization BioMendics, LLC (US) 2022-09-22 US disclosed
US-11351126-B2 Substituted tolans for the modulation of microbial colonization BioMendics, LLC (US) 2022-06-07 US disclosed
US-20210228501-A1 Formulation and Process for Modulating Wound Healing BioMendics, LLC (US) 2021-07-29 US disclosed
CN-111526873-A Substituted tolanes for regulating microbial colonization 生物曼迪克斯有限责任公司 2020-08-11 CN disclosed
US-20200206154-A1 Substituted Tolans for the Modulation of Microbial Colonization BioMendics, LLC (US) 2020-07-02 US disclosed
EP-2880033-B1 CYCLIC UREA- OR LACTAM-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND THE USES THEREOF PURDUE PHARMA LP (US) 2020-06-17 EP disclosed
WO-2011103932-A1 A PROCESS FOR THE PREPARATION OF SUBSTITUTED PROLYL PEPTIDES AND SIMILAR PEPTIDOMIMETICS VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS, WETENSCHAPPELIJK ONDERZOEK EN PATIËNTENZORG (NL) 2011-09-01 WO disclosed
EP-2307419-A2 BIOCATALYTIC PROCESSES FOR THE PREPARATION OF SUBSTANTIALLY STEREOMERICALLY PURE FUSED BICYCLIC PROLINE COMPOUNDS Codexis, Inc. (US) 2011-04-13 EP disclosed
US-20100324080-A1 Benzomorphan Compounds PURDUE PHARMA L.P. (US) 2010-12-23 US disclosed
EP-2225246-A1 BENZOMORPHAN COMPOUNDS Purdue Pharma LP (US) 2010-09-08 EP disclosed
US-20100216726-A1 Substituted-Quinoxaline-Type Piperidine Compounds and the Uses Thereof PURDUE PHARMA L.P. (US) 2010-08-26 US disclosed
US-20100063300-A1 BIOCATALYTIC PROCESSES FOR THE PREPARATION OF SUBSTANTIALLY STEREOMERICALLY PURE FUSED BICYCLIC PROLINE COMPOUNDS CODEXIS, INC. (US) 2010-03-11 US disclosed
WO-2010008828-A2 BIOCATALYTIC PROCESSES FOR THE PREPARATION OF SUBSTANTIALLY STEREOMERICALLY PURE FUSED BICYCLIC PROLINE COMPOUNDS CODEXIS, INC. (US) 2010-01-21 WO disclosed
EP-2086958-A2 SUBSTITUTED-QUINOXALINE-TYPE-PIPERIDINE COMPOUNDS AND THE USES THEREOF Purdue Pharma LP (US) 2009-08-12 EP disclosed
WO-2009068989-A1 BENZOMORPHAN COMPOUNDS PURDUE PHARMA L.P. (DE) 2009-06-04 WO disclosed
WO-2009027820-A2 SUBSTITUTED-QUINOXALINE-TYPE-PIPERIDINE COMPOUNDS AND THE USES THEREOF PURDUE PHARMA L.P. (DE) 2009-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100063300-A1 BIOCATALYTIC PROCESSES FOR THE PREPARATION OF SUBSTANTIALLY STEREOMERICALLY PURE FUSED BICYCLIC PROLINE COMPOUNDS PREP, PEPD, COASY ALDH1A1 909/4885
US-20100216726-A1 Substituted-Quinoxaline-Type Piperidine Compounds and the Uses Thereof P2RX4, P2RX5, P2RX3 ALDH1A1 889/4885
US-20100324080-A1 Benzomorphan Compounds OPRM1, OPRK1, OPRD1 ALDH1A1 1221/4885
US-11786481-B2 Formulation and process for modulating wound healing SQSTM1, ATG7, TFEB ALDH1A1 2877/4885
US-20200206154-A1 Substituted Tolans for the Modulation of Microbial Colonization LMAN1, DPM1, DSTN ALDH1A1 1348/4885
US-20210228501-A1 Formulation and Process for Modulating Wound Healing ATG7, SQSTM1, ATF4 ALDH1A1 2362/4885
US-11351126-B2 Substituted tolans for the modulation of microbial colonization LMAN1, DPM1, DSTN ALDH1A1 1348/4885
US-20220296538-A1 Substituted Tolans for the Modulation of Microbial Colonization LMAN1, DPM1, DSTN ALDH1A1 1348/4885
US-20230130617-A1 PROCESS FOR IMPROVED OPIOID SYNTHESIS OPRK1, OPRM1, OPRD1 ALDH1A1 1749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.