SCHEMBL853302

SCHEMBL853302

COCCNC(=O)c1ccc(N)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.66
ALDH1A1 P00352 2/20 0.66
LMNA P02545 2/20 0.59
SLC22A2 O15244 1/20 0.59
SLC22A1 O15245 1/20 0.59
TSHR P16473 1/20 0.59
ACHE P22303 1/20 0.59
MAPK1 P28482 1/20 0.59
CYP2C19 P33261 1/20 0.59
BLM P54132 1/20 0.58
PMP22 Q01453 1/20 0.58
KMT2A Q03164 3/20 0.57
KDM4E B2RXH2 1/20 0.56
MAPT P10636 1/20 0.56
HIF1A Q16665 1/20 0.56
SLC22A6 Q4U2R8 1/20 0.56
SLC22A8 Q8TCC7 1/20 0.56
ESRRG P62508 1/20 0.55
NPC1 O15118 4/20 0.53
HDAC3 O15379 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3709030 0.90 ALDH1A1 (0.83) HPGDALDH1A1LMNASLC22A2SLC22A1
SCHEMBL2317132 0.86 HPGD (0.66) HPGDALDH1A1KMT2AMAPTNPC1
SCHEMBL9344489 0.85 KDM4E (0.68) ALDH1A1LMNASLC22A2SLC22A1TSHR
SCHEMBL23470985 0.84 HPGD (0.73) HPGDALDH1A1LMNATSHRMAPK1
SCHEMBL4694425 0.84 ALDH1A1 (0.68) HPGDALDH1A1KMT2AMAPTNPC1
SCHEMBL4506194 0.84 ALDH1A1 (0.68) HPGDALDH1A1CYP2C19BLMPMP22
SCHEMBL757478 0.84 NPC1 (0.73) HPGDALDH1A1LMNAKMT2AMAPT
SCHEMBL16218305 0.83 HDAC3 (0.58) HPGDALDH1A1LMNASLC22A2SLC22A1
SCHEMBL24809306 0.83 SMN1; SMN2 (0.57) HPGDALDH1A1LMNASLC22A2SLC22A1
SCHEMBL19634404 0.83 LOXL2 (0.64) HPGDALDH1A1KMT2ANPC1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12582588-B2 Solid cosmetic composition for blocking ultraviolet radiation having water resistance and cleansing properties LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2026-03-24 US claimed
US-12502348-B2 Ultraviolet blocking cosmetic composition in chromatic emulsion state LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2025-12-23 US claimed
WO-2024122465-A1 EMULSIFIED TOPICAL COMPOSITION AND METHOD FOR PRODUCING SAME ロート製薬株式会社 2024-06-13 WO claimed
WO-2023189896-A1 COSMETIC 信越化学工業株式会社 2023-10-05 WO claimed
US-20230233428-A1 SOLID COSMETIC COMPOSITION FOR BLOCKING ULTRAVIOLET RADIATION HAVING WATER RESISTANCE AND CLEANSING PROPERTIES LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2023-07-27 US claimed
WO-2023063102-A1 COSMETIC COMPOSITION 株式会社 資生堂 2023-04-20 WO claimed
US-20220378674-A1 WATER-IN-OIL COSMETIC COMPOSITION WITH MAXIMIZED FEELING OF MOISTURE KOLMAR KOREA CO., LTD. (KR) 2022-12-01 US claimed
US-20220287951-A1 Ultraviolet Blocking Cosmetic Composition In Chromatic Emulsion State LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2022-09-15 US claimed
WO-2022190965-A1 BEAUTY METHOD 株式会社 資生堂 2022-09-15 WO claimed
EP-4019001-A1 WATER-IN-OIL COSMETIC COMPOSITION WITH MAXIMIZED MOIST FEELING Kolmar Korea Co., Ltd. (KR) 2022-06-29 EP claimed
US-20160002154-A1 UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN ISP INVESTMENTS INC. (US) 2016-01-07 US claimed
US-20150265522-A1 POLYMER-BOUND UV ABSORBERS IN PERSONAL CARE COMPOSITIONS ISP INVESTMENTS INC. (US) 2015-09-24 US claimed
US-9044623-B2 Polymer-bound UV absorbers in personal care compositions ISP INVESTMENTS INC. (US) 2015-06-02 US claimed
WO-2014149363-A1 UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN ISP INVESTMENTS INC. (US) 2014-09-25 WO claimed
US-20140134221-A1 AGENT FOR PROVIDING POSITIVE SURFACE CHARGE ON UV PROTECTION VESICLES AIR PRODUCTS SCHLÜCHTERN GMBH (DE) 2014-05-15 US claimed
US-20140023601-A1 PERFORMANCE BOOSTING UV-ABSORBING COMPOUNDS ISP INVESTMENT INC. (US) 2014-01-23 US claimed
US-8557226-B2 Performance-boosting UV-absorbing compounds ISP INVESTMENTS INC. (US) 2013-10-15 US claimed
US-20110200666-A1 UV PROTECTION AGENT FOR THE SKIN OR HAIR HAVING A UV FILTER SUBSTANCE ENCAPSULATED IN A VESICULAR CARRIER SYSTEMü ROVI COSMETICS INTERNATIONAL GMBH (DE) 2011-08-18 US claimed
US-20100189661-A1 POLYMER-BOUND UV ABSORBERS IN PERSONAL CARE COMPOSITIONS PHARMACHEM LABORATORIES LLC 2010-07-29 US claimed
US-20100183532-A1 Performance-Boosting UV-Absorbing Compounds HERCULES LLC 2010-07-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110200666-A1 UV PROTECTION AGENT FOR THE SKIN OR HAIR HAVING A UV FILTER SUBSTANCE ENCAPSULATED IN A VESICULAR CARRIER SYSTEMü HNRNPU, CD44, CUTA HPGD 3134/4885ALDH1A1 1789/4885LMNA 1485/4885
US-20100189661-A1 POLYMER-BOUND UV ABSORBERS IN PERSONAL CARE COMPOSITIONS CUTA, UACA, LAGE3 HPGD 3599/4885ALDH1A1 605/4885LMNA 33/4885
US-20140134221-A1 AGENT FOR PROVIDING POSITIVE SURFACE CHARGE ON UV PROTECTION VESICLES CD44, CD63, CTSA HPGD 3609/4885ALDH1A1 1518/4885LMNA 1043/4885
US-20100183532-A1 Performance-Boosting UV-Absorbing Compounds APOB, ALOX5, RARG HPGD 1487/4885ALDH1A1 118/4885LMNA 2251/4885
US-12582588-B2 Solid cosmetic composition for blocking ultraviolet radiation having water resistance and cleansing properties CUTA, TRPA1, ERCC5 HPGD 650/4885ALDH1A1 645/4885LMNA 3198/4885
US-20150265522-A1 POLYMER-BOUND UV ABSORBERS IN PERSONAL CARE COMPOSITIONS CUTA, UACA, LAGE3 HPGD 3599/4885ALDH1A1 605/4885LMNA 33/4885
US-20160002154-A1 UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN ERCC1, ERCC4, UNG HPGD 63/4885ALDH1A1 263/4885LMNA 1648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.