Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | HPGD | P15428 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 4/20 | 0.36 |
| ▸ | BLM | P54132 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8593809 | 0.85 | FBP1 (0.40) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8555909 | 0.84 | EGFR (0.33) | EGFRDNM1ALDH1A1HPGDKDM4E | |
| SCHEMBL8547870 | 0.83 | PDCD1 (0.43) | EGFRALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL8550020 | 0.83 | GAA (0.48) | EGFRALDH1A1HPGDKDM4EMAPK1 | |
| SCHEMBL8553056 | 0.82 | DNM1 (0.35) | EGFRDNM1ALDH1A1HPGDKDM4E | |
| SCHEMBL8554588 | 0.80 | TRPA1 (0.38) | EGFRDNM1ALDH1A1HPGDKDM4E | |
| SCHEMBL8554286 | 0.80 | PYGL (0.42) | ALDH1A1HPGDKDM4ESMN1; SMN2POLB | |
| SCHEMBL8144746 | 0.80 | DNM1 (0.37) | DNM1ALDH1A1HPGDTDP1CYP1A2 | |
| SCHEMBL8551274 | 0.79 | PLAAT3 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL8552707 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KDM4ESMN1; SMN2CYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |