Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624424 | 0.76 | EGFR (0.39) | MAPTKDM4EHTTRAB9ANPSR1 | |
| SCHEMBL8552834 | 0.66 | NPC1 (0.31) | MAPTKDM4ENPC1S1PR4S1PR1 | |
| SCHEMBL8552830 | 0.65 | RAB9A (0.37) | HTTRAB9ALMNAKMT2ASIGMAR1 | |
| SCHEMBL8554881 | 0.64 | ALDH1A1 (0.35) | MAPTRAB9ALMNAGAA | |
| SCHEMBL8554052 | 0.60 | LMNA (0.37) | MAPTNPC1RAB9ALMNAPOLB | |
| SCHEMBL8554050 | 0.60 | RAB9A (0.42) | MAPTHTTRAB9ALMNAPOLB | |
| SCHEMBL9770602 | 0.59 | CTSB (0.49) | MAPTKDM4EHTTLMNAPOLB | |
| SCHEMBL8558985 | 0.57 | TSHR (0.45) | NPC1RAB9ALMNAPOLBKMT2A | |
| SCHEMBL3342318 | 0.57 | TSHR (0.51) | MAPTKDM4ENPC1S1PR4S1PR1 | |
| SCHEMBL8566829 | 0.57 | MAPT (0.43) | MAPTKDM4ENPC1S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | disclosed |