Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816397 | 0.82 | CYP3A4 (0.41) | CA1CA2CYP3A4TSHRCYP2C9 | |
| Hydrochloric Acid SCHEMBL7472111 | 0.81 | CYP3A4 (0.43) | CA1CA2CYP3A4TSHRCYP2C9 | |
| SCHEMBL6816877 | 0.81 | ALDH3A1 (0.58) | CA1CA2CYP3A4TSHRCYP2C9 | |
| SCHEMBL8640578 | 0.81 | CASP1 (0.35) | TSHRALDH1A1THRBCASP1RECQL | |
| SCHEMBL6574139 | 0.79 | PLA2G7 (0.50) | CYP3A4TSHRCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL20776804 | 0.79 | NR1H2 (0.43) | KMT2AMEN1 | |
| SCHEMBL10810768 | 0.79 | ALDH3A1 (0.47) | CA1CA2CYP3A4TSHRCYP2C9 | |
| SCHEMBL6571903 | 0.78 | KMT2A (0.38) | ALDH1A1HPGDHSD17B10KMT2AMAPT | |
| SCHEMBL6739710 | 0.78 | CYP3A4 (0.34) | CA1CA2CYP3A4TSHRCYP2C9 | |
| SCHEMBL6573366 | 0.78 | CYP3A4 (0.42) | CYP3A4TSHRKMT2AKCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1473025-B1 | Dyeing composition containing 2-chloro-6-methyl-3-aminophenol and an associative polymer | OREAL (FR) | 2012-03-28 | — | — | EP | claimed |
| US-7306630-B2 | Composition comprising at least one coupler chosen from 2-chloro-6-methyl-3-aminophenol and addition salts thereof, at least one oxidation base, and at least one associative polymer comprising at least one C8-C30 fatty chain | L'OREAL S.A. (FR) | 2007-12-11 | — | — | US | claimed |
| WO-2007071686-A1 | COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, AN OXIDATION BASE AND A PARTICULAR COUPLER | L'ORÉAL (FR) | 2007-06-28 | — | — | WO | claimed |
| US-7141078-B2 | Oxidation dyeing composition for keratinous fiber and dyeing method using same | L′Oreal (FR) | 2006-11-28 | — | — | US | claimed |
| US-7141079-B2 | Oxidation dyeing composition for keratinous fibers and dyeing method using same | L′Oreal (FR) | 2006-11-28 | — | — | US | claimed |
| EP-1274393-B1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND METHOD USING SAME | OREAL (FR) | 2006-07-05 | — | — | EP | claimed |
| US-20050028302-A1 | Dye composition comprising at least one oxidation base, 2-chloro-6-methyl-3-aminophenol and 3-methyl-1-phenyl-5-pyrazolone | L'OREAL S.A. (FR) | 2005-02-10 | — | — | US | claimed |
| US-20050000039-A1 | Composition comprising at least one coupler chosen from 2-chloro-6-methyl-3-aminophenol and addition salts thereof, at least one oxidation base, and at least one associative polymer comprising at least one C8-C30 fatty chain | L'OREAL S.A. (FR) | 2005-01-06 | — | — | US | claimed |
| US-20040194232-A1 | Oxidizing composition and uses for dyeing, for permanently reshaping or for bleaching keratin fibers | L'OREAL S.A. | 2004-10-07 | — | — | US | claimed |
| US-6783559-B2 | AT LEAST ONE FIRST OXIDATION BASE, AT LEAST ONE SECOND OXIDATION BASE CHOSEN FROM PARA-AMINOPHENOLS, AT LEAST ONE META-AMINOPHENOL AS COUPLER AND AT LEAST ONE ENZYME OF 2-ELECTRON OXIDOREDUCTASE TYPE IN THE PRESENCE OF AT LEAST ONE | L'OREAL S.A. (FR) | 2004-08-31 | — | — | US | claimed |
| US-20010049850-A1 | Mixture containing 2-amino-3-hydroxypyridine coupler and oxidoreductase enzyme | L'OREAL S.A. (FR) | 2001-12-13 | — | — | US | claimed |
| US-6312479-B1 | OXIDATION BASE; COUPLER CHOSEN FROM 2-AMINO-3-HYDROXYPYRIDINES AND ACID-ADDITION SALTS THEREOF; A 2-ELECTRON OXIDOREDUCTASE; AND A DONOR FOR SAID ENZYME. | L'OREAL S.A. (FR) | 2001-11-06 | — | — | US | claimed |
| EP-0974336-B1 | Composition for oxidative dying of keratinous fibres and dying process therewith | OREAL (FR) | 2001-09-12 | — | — | EP | claimed |
| US-6241784-B1 | COSMETICS OR SKIN COMPOSITION FOR TREATING FIBERS | L'OREAL S.A. (FR) | 2001-06-05 | — | — | US | claimed |
| US-6228129-B1 | OXIDATION BASE, CATIONIC DIRECT DYE AND AN ENZYME OF 2-ELECTRON OXIDOREDUCTASES IN THE PRESENCE OF A DONOR FOR THE ENZYME | L'OREAL S.A. (FR) | 2001-05-08 | — | — | US | claimed |
| EP-1077929-A1 | 2,3,5-SUBSTITUTED BIPHENYLS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-02-28 | — | — | EP | claimed |
| US-6152967-A | COMPOSITION FOR HAIR DYEING COMPRISING AT LEAST ONE OXIDATION BASE AND BILIRUBIN OXIDASE | L'OREAL (FR) | 2000-11-28 | — | — | US | claimed |
| US-6099590-A | READY-TO-USE COMPOSITION COMPRISING OXIDATION BASE(S), CHOLINE OXIDASE(S), AND DONOR(S) FOR THE CHOLINE OXIDASE; MULTICOMPARTMENT DYE KITS; PROCESS FOR DYEING; STRONGER COLORATIONS | L'OREAL (FR) | 2000-08-08 | — | — | US | claimed |
| US-6090159-A | READY-TO-USE OXIDATION DYEING COMPOSITION COMPRISING AN OXIDATION BASE, SARCOSINE OXIDASE AS OXIDIZER, AND AT LEAST ONE DONOR FOR THE ENZYME; STRONGER COLORATION, NO BLEACHING | L'OREAL (FR) | 2000-07-18 | — | — | US | claimed |
| WO-1999061410-A1 | 2,3,5-SUBSTITUTED BIPHENYLS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-12-02 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010049850-A1 | Mixture containing 2-amino-3-hydroxypyridine coupler and oxidoreductase enzyme | POR, QDPR, DPYD | CA1 1401/4885CA2 668/4885CYP3A4 339/4885 |
| US-20050000039-A1 | Composition comprising at least one coupler chosen from 2-chloro-6-methyl-3-aminophenol and addition salts thereof, at least one oxidation base, and at least one associative polymer comprising at least one C8-C30 fatty chain | FABP4, KRT18, S100A10 | CA1 1007/4885CA2 751/4885CYP3A4 1530/4885 |
| US-20040194232-A1 | Oxidizing composition and uses for dyeing, for permanently reshaping or for bleaching keratin fibers | KRT18, ALDH1A2, PPOX | CA1 1417/4885CA2 887/4885CYP3A4 998/4885 |
| US-20050028302-A1 | Dye composition comprising at least one oxidation base, 2-chloro-6-methyl-3-aminophenol and 3-methyl-1-phenyl-5-pyrazolone | KRT18, COX5A, COX5B | CA1 3648/4885CA2 2521/4885CYP3A4 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.