Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | PPIB | P23284 | 1/20 | 0.51 |
| ▸ | PPIA | P62937 | 1/20 | 0.51 |
| ▸ | PPID | Q08752 | 1/20 | 0.51 |
| ▸ | PPIG | Q13427 | 1/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23149729 | 0.86 | PARP10 (0.53) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL572 | 0.85 | KMT2A (0.58) | LMNAALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL6650021 | 0.84 | LMNA (0.61) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL8585196 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KMT2AKDM4EMEN1MGAM | |
| SCHEMBL8085697 | 0.84 | CA12 (0.61) | ALDH1A1KMT2AKDM4EMEN1MGAM | |
| SCHEMBL11515591 | 0.84 | TSHR (0.66) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL10745284 | 0.83 | USP5 (0.51) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL13516645 | 0.82 | ALDH1A1 (0.55) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL314260 | 0.82 | KMT2A (0.54) | LMNACYP1A2ALDH1A1KMT2AKDM4E | |
| SCHEMBL276803 | 0.82 | SMN1; SMN2 (0.61) | LMNAALDH1A1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102718757-A | 2H-1-benzopyran-2-one compounds with alpha-glucosidase inhibitory activity and medicinal composition of 2H-1-benzopyran-2-one compounds | UNIV SHENYANG PHARMACEUTICAL | 2012-10-10 | — | — | CN | claimed |
| US-10093658-B2 | Bifunctional compounds and use for reducing uric acid levels | ACQUIST LLC (US) | 2018-10-09 | — | — | US | disclosed |
| US-20180002315-A1 | Bifunctional Compounds and Use for Reducing Uric Acid Levels | ACQUIST LLC | 2018-01-04 | — | — | US | disclosed |
| EP-3247704-A1 | BIFUNCTIONAL COMPOUNDS AND USE FOR REDUCING URIC ACID LEVELS | Warrell, Raymond P., Jr. (US) | 2017-11-29 | — | — | EP | disclosed |
| WO-2016118611-A1 | BIFUNCTIONAL COMPOUNDS AND USE FOR REDUCING URIC ACID LEVELS | WARRELL RAYMOND P JR (US) | 2016-07-28 | — | — | WO | disclosed |
| CN-102718757-B | 2H-1-benzopyran-2-one compounds with alpha-glucosidase inhibitory activity and medicinal composition of 2H-1-benzopyran-2-one compounds | UNIV SHENYANG PHARMACEUTICAL | 2014-05-21 | — | — | CN | disclosed |
| CN-102718757-A | 2H-1-benzopyran-2-one compounds with alpha-glucosidase inhibitory activity and medicinal composition of 2H-1-benzopyran-2-one compounds | UNIV SHENYANG PHARMACEUTICAL | 2012-10-10 | — | — | CN | disclosed |
| EP-2216335-A1 | TETRIACYCLODIPYRANYL COUMARINS AND THE ANTI-HIV AND ANTI-TUBERCULOSIS USES THEREOF | Institute of Mataria Medica, Chinese Academy of Medical Sciences (CN) | 2010-08-11 | — | — | EP | disclosed |
| EP-0519306-B1 | Oil-dispersed yellow filter dyes | FUJI PHOTO FILM CO LTD (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-5296344-A | Silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| US-5274162-A | Antineoplastic drugs with bipolar toxification/detoxification functionalities | GLAZIER ARNOLD (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0519306-A1 | Oil-dispersed yellow filter dyes | FUJI PHOTO FILM CO., LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |
| EP-0198356-B1 | HEAT DEVELOPABLE LIGHT-SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1989-07-26 | — | — | EP | disclosed |
| EP-0177033-B1 | HEAT-DEVELOPABLE LIGHT-SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |
| US-4764458-A | CONTAINING ORGANIC SILVER SALT OF UNSATURATED AROMATIC CARBOXYLATE | FUJI PHOTO FILM CO., LTD. (JP) | 1988-08-16 | — | — | US | disclosed |
| US-4657848-A | STORAGE STABILITY, ANTIFOGGING, HIGH DENSITY IMAGE | FUJI PHOTO FILM CO., LTD. (JP) | 1987-04-14 | — | — | US | disclosed |
| EP-0198356-A1 | Heat developable light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1986-10-22 | — | — | EP | disclosed |
| EP-0177033-A2 | Heat-developable light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1986-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10093658-B2 | Bifunctional compounds and use for reducing uric acid levels | XDH, ATIC, DUOX2 | LMNA 3552/4885CYP1A2 379/4885CYP3A4 813/4885 |
| US-20180002315-A1 | Bifunctional Compounds and Use for Reducing Uric Acid Levels | XDH, ATIC, DUOX2 | LMNA 3552/4885CYP1A2 379/4885CYP3A4 813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.