SCHEMBL8623348

SCHEMBL8623348

COC(C)(OC)O[Al+2].[H-].[H-].[H-].[Na+]

nearest known ligand 0.00

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL90785 0.69
SCHEMBL732372 0.67
SCHEMBL875871 0.65
Hydrochloric Acid SCHEMBL28181771 0.65
SCHEMBL11318871 0.64
SCHEMBL452898 0.62
Lithium Ion SCHEMBL452900 0.62
Potassium Ion SCHEMBL27292164 0.62
SCHEMBL238147 0.62 ALDH1A1 (0.46)
SCHEMBL11786771 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0502439-B1 Purification of 6-Aminocapronitrile DU PONT (US) 1994-09-14 EP claimed
EP-0502439-A1 Purification of 6-Aminocapronitrile E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-09-09 EP claimed
US-5133838-A PURIFICATION OF 6-AMINOCAPRONITRILE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-07-28 US claimed
JP-10045660-A None JP disclosed
JP-H1045660-A PRODUCTION OF KETOALDEHYDE TOYOTAMA KORYO KK 1998-02-17 JP disclosed
EP-0502439-B1 Purification of 6-Aminocapronitrile DU PONT (US) 1994-09-14 EP disclosed
EP-0502439-A1 Purification of 6-Aminocapronitrile E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-09-09 EP disclosed
US-5133838-A PURIFICATION OF 6-AMINOCAPRONITRILE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-07-28 US disclosed