SCHEMBL8635950

SCHEMBL8635950

CCCC(C)c1ccc(Oc2ccc(OCC=C(Cl)Cl)c(C(F)(F)F)c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.34
PPARA Q07869 3/20 0.34
PPARD Q03181 2/20 0.34
FFAR4 Q5NUL3 1/20 0.33
AR P10275 5/20 0.32
FFAR1 O14842 1/20 0.32
ALOX5 P09917 2/20 0.32
PSEN1 P49768 1/20 0.32
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31
HTT P42858 1/20 0.31
UBE2M P61081 1/20 0.31
DCUN1D1 Q96GG9 1/20 0.31
PTGES O14684 1/20 0.31
CYP17A1 P05093 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8635276 0.92 ALDH1A1 (0.36) FFAR4ARFFAR1HTTCYP17A1
SCHEMBL8634549 0.90 THRA (0.33) PPARGPPARAPPARDARFFAR1
SCHEMBL8635558 0.84 LTA4H (0.43) PPARGPPARAPPARDARALOX5
SCHEMBL8635519 0.84 LTA4H (0.43) PPARGPPARAPPARDALOX5PSEN1
SCHEMBL8634403 0.84 FFAR4 (0.43) PPARGPPARAPPARDFFAR4AR
SCHEMBL8635048 0.83 MAPT (0.44) ARHTTRXRARXRBRXRG
SCHEMBL8633073 0.82 L3MBTL1 (0.39) ARHTTLMNAMAPTATM
SCHEMBL8634174 0.81 AR (0.39) PPARGPPARAPPARDFFAR4AR
SCHEMBL8636474 0.81 RXRA (0.38) PPARGPPARDARFFAR1ALOX5
SCHEMBL8634067 0.81 ALDH1A1 (0.36) ARFFAR1CYP17A1CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed