SCHEMBL866046

SCHEMBL866046

FC(F)(OC(F)(F)C(Cl)Cl)C(Cl)Cl

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11620323 0.87 MEN1 (0.38) MEN1KMT2A
SCHEMBL9154522 0.74 MEN1 (0.43) MEN1KMT2AALDH1A1HSD17B10
SCHEMBL2760958 0.72 MEN1 (0.41) MEN1KMT2AALDH1A1HSD17B10
Methoxyflurane SCHEMBL121229 0.72
SCHEMBL1991659 0.70
Methoxyflurane SCHEMBL27525605 0.69
SCHEMBL11419898 0.69 MEN1 (0.39) MEN1KMT2A
SCHEMBL20772959 0.65
SCHEMBL9066678 0.65 ALDH1A1 (0.54) MEN1KMT2AALDH1A1HSD17B10
SCHEMBL65852 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12551570-B2 Compounds comprising cleavable linker and uses thereof INTOCELL, INC. (KR) 2026-02-17 US disclosed
US-12479927-B2 Compounds comprising cleavable linker and uses thereof INTOCELL, INC. (KR) 2025-11-25 US disclosed
US-20250213712-A1 ANTIBODY DRUG CONJUGATES COMPRISING CAMPTOTHECIN DERIVATIVES AND USES THEREOF INTOCELL, INC. (KR) 2025-07-03 US disclosed
US-12274898-B2 Substituted benzodiazepines as antibody-drug conjugates INTOCELL, INC. (KR) 2025-04-15 US disclosed
EP-4452328-A1 ANTIBODY DRUG CONJUGATES COMPRISING TOXINS WITH POLAR GROUPS AND USES THEREOF Intocell, Inc. (KR) 2024-10-30 EP disclosed
US-20230406877-A1 COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF INTOCELL, INC. (KR) 2023-12-21 US disclosed
US-11807628-B2 Benzodiazepine derivatives and uses thereof INTOCELL, INC. (KR) 2023-11-07 US disclosed
US-11753431-B2 Compounds comprising cleavable linker and uses thereof INTOCELL, INC. (KR) 2023-09-12 US disclosed
WO-2023118961-A1 ANTIBODY DRUG CONJUGATES COMPRISING TOXINS WITH POLAR GROUPS AND USES THEREOF INTOCELL, INC. (KR) 2023-06-29 WO disclosed
US-20230190939-A1 ANTIBODY DRUG CONJUGATES COMPRISING TOXINS WITH POLAR GROUPS AND USES THEREOF INTOCELL, INC. (KR) 2023-06-22 US disclosed
WO-2008061032-A1 OPTICAL DATA RECORDING AND IMAGING ON MEDIA USING APOCHROMATIC LENSES HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2008-05-22 WO disclosed
WO-2008061030-A1 OPTICAL DATA RECORDING AND IMAGING ON MEDIA USING APOCHROMATIC LENSES AND A LIGHT SEPARATING MEANS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2008-05-22 WO disclosed
US-20080050672-A1 LIGHT ACTIVATED CONTRAST SYSTEMS USING MASKED DEVELOPERS FOR OPTICAL DATA RECORDING HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2008-02-28 US disclosed
WO-2008024984-A1 LIGHT ACTIVATED CONTRAST SYSTEMS USING MASKED DEVELOPERS FOR OPTICAL DATA RECORDING HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2008-02-28 WO disclosed
US-20070265296-A1 Nuclear receptor binding agents GTX, INC. 2007-11-15 US disclosed
WO-2007062230-A2 NUCLEAR RECEPTOR BINDING AGENTS GTX, INC. (US) 2007-05-31 WO disclosed
US-20050254551-A1 Temperature monitoring system HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2005-11-17 US disclosed
US-6958181-B1 Protected activators for use in leuco dye compositions HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2005-10-25 US disclosed
US-20050227034-A1 PROTECTED ACTIVATORS FOR USE IN LEUCO DYE COMPOSITIONS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2005-10-13 US disclosed
WO-2005025885-A1 PROTECTED ACTIVATORS FOR USE IN LEUCO DYE COMPOSITIONS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2005-03-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190939-A1 ANTIBODY DRUG CONJUGATES COMPRISING TOXINS WITH POLAR GROUPS AND USES THEREOF CD47, ENPP2, CD2 MEN1 1660/4885KMT2A 3159/4885ALDH1A1 4468/4885
US-11807628-B2 Benzodiazepine derivatives and uses thereof GABRB3, GABRB2, GABRB1 MEN1 3799/4885KMT2A 1869/4885ALDH1A1 900/4885
US-20250213712-A1 ANTIBODY DRUG CONJUGATES COMPRISING CAMPTOTHECIN DERIVATIVES AND USES THEREOF CD47, TOP2A, SSB MEN1 1190/4885KMT2A 2535/4885ALDH1A1 2732/4885
US-12551570-B2 Compounds comprising cleavable linker and uses thereof FCGR2A, FCGR3B, FCGR1A MEN1 3990/4885KMT2A 3562/4885ALDH1A1 4586/4885
US-20070265296-A1 Nuclear receptor binding agents GPER1, ESRRG, ESR2 MEN1 1408/4885KMT2A 1506/4885ALDH1A1 3644/4885
US-20230406877-A1 COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF VIP, ANTXR2, TNFRSF9 MEN1 3064/4885KMT2A 3544/4885ALDH1A1 4822/4885
US-12479927-B2 Compounds comprising cleavable linker and uses thereof VIP, ANTXR2, TNFRSF9 MEN1 3064/4885KMT2A 3544/4885ALDH1A1 4822/4885
US-11753431-B2 Compounds comprising cleavable linker and uses thereof VIP, ANTXR2, TNFRSF9 MEN1 3064/4885KMT2A 3544/4885ALDH1A1 4822/4885
US-12274898-B2 Substituted benzodiazepines as antibody-drug conjugates GABRA3, GABRA6, GABRA4 MEN1 3404/4885KMT2A 828/4885ALDH1A1 207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.