SCHEMBL871816

SCHEMBL871816

CC(C)(O)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 3/20 0.36
GRIN3B O60391 3/20 0.36
GRIN1 Q05586 3/20 0.36
GRIN2A Q12879 3/20 0.36
GRIN2B Q13224 3/20 0.36
GRIN2C Q14957 3/20 0.36
GRIN3A Q8TCU5 3/20 0.36
LMNA P02545 3/20 0.35
SIGMAR1 Q99720 2/20 0.35
SLC22A2 O15244 2/20 0.35
SLC47A1 Q96FL8 2/20 0.35
SLC22A1 O15245 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
STAT6 P42226 1/20 0.35
GAA P10253 1/20 0.33
HSD11B1 P28845 1/20 0.33
POLB P06746 1/20 0.33
THRB P10828 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12834762 0.87 HSD11B1 (0.39) HSD11B1
SCHEMBL12296586 0.85 HSD11B1 (0.31) HSD11B1MEN1CYP2D6CYP2C19KMT2A
SCHEMBL5193595 0.84 THRB (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1771080 0.82
SCHEMBL26707785 0.79 GRIN2D (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL11911862 0.79 PKM (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL6504614 0.79 EPHX2 (0.44) TSHRHSD11B1EPHX2
SCHEMBL14695704 0.77 TSHR (0.40) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2688294 0.77 PKM (0.45) HSD11B1THRB
SCHEMBL2825436 0.77 GRIN2D (0.45) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105385202-A Waterproof agent for swimming pool YANTAI SHUNLONG CHEMICAL TECH CO LTD 2016-03-09 CN claimed
CN-104830513-A Semi-synthetic metal cutting fluid YANTAI SHUNLONG CHEMICAL ENGINEERING TECHNOLOGY CO LTD 2015-08-12 CN claimed
EP-2231670-A2 PROCESS FOR THE PREPARATION OF 2-(PRIMARY/SECONDARY AMINO)HYDROCARBYL)- CARBAMOYL-7-OXO-2,6-DIAZA-BICYCLOÝ3.2.0.¨HEPTANE-6-SULFONIC ACID DERIVATIVES Basilea Pharmaceutica AG (CH) 2010-09-29 EP claimed
WO-2009071638-A2 PROCESS FOR THE PREPARATION OF 2-(PRIMARY/SECONDARY AMINO)HYDROCARBYL)- CARBAMOYL-7-OXO-2,6-DIAZA-BICYCLO[3.2.0.]HEPTANE-6-SULFONIC ACID DERIVATIVES BASILEA PHARMACEUTICA AG (CH) 2009-06-11 WO claimed
US-12240857-B2 Adamantane derivatives for the treatment of filovirus infection ARISAN THERAPEUTICS INC. (US) 2025-03-04 US disclosed
US-11377415-B2 Method for converting N,N-dialkylamide compound into ester compound using complex of fourth-period transition metal as catalyst TAKASAGO INTERNATIONAL CORPORATION (JP) 2022-07-05 US disclosed
US-11161869-B2 Thermally-cleavable protecting and linker groups EVONETIX LTD. (GB) 2021-11-02 US disclosed
US-20210107934-A1 THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS SILICON VALLEY BANK 2021-04-15 US disclosed
EP-3760607-A1 METHOD FOR CONVERTING N,N-DIALKYLAMIDE COMPOUND INTO ESTER COMPOUND USING COMPLEX OF FOURTH-PERIOD TRANSITION METAL AS CATALYST Takasago International Corporation (JP) 2021-01-06 EP disclosed
US-20200399200-A1 METHOD FOR CONVERTING N,N-DIALKYLAMIDE COMPOUND INTO ESTER COMPOUND USING COMPLEX OF FOURTH-PERIOD TRANSITION METAL AS CATALYST TAKASAGO INTERNATIONAL CORPORATION (JP) 2020-12-24 US disclosed
EP-3609866-A1 THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS Evonetix Ltd (GB) 2020-02-19 EP disclosed
EP-3405183-A1 ADAMATANE DERIVATIVES FOR THE TREATMENT OF FILOVIRUS INFECTION Arisan Therapeutics Inc. (US) 2018-11-28 EP disclosed
US-20020016516-A1 Hydrocarbon bonded to a carbon atom which is bonded to a hydroxyl group, a methane group, and an adamantane ring; or its protected derivatives; alcohol intermediates for acrylic ester monomers for hydrophilic, adhesive photoresists DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-02-07 US disclosed
US-6344590-B1 HYDROCARBON BONDED TO A CARBON ATOM WHICH IS BONDED TO A HYDROXYL GROUP, A METHANE GROUP, AND AN ADAMANTANE RING; OR ITS PROTECTED DERIVATIVES; ALCOHOL INTERMEDIATES FOR ACRYLIC ESTER MONOMERS FOR HYDROPHILIC, ADHESIVE PHOTORESISTS DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-02-05 US disclosed
EP-1055654-A1 PROCESS FOR THE PREPARATION OF ORGANIC COMPOUNDS WITH IMIDE CATALYSTS Daicel Chemical Industries, Ltd. (JP) 2000-11-29 EP disclosed
EP-1043298-A1 PROCESSES FOR THE PREPARATION OF ALCOHOLS Daicel Chemical Industries, Ltd. (JP) 2000-10-11 EP disclosed
EP-0990632-A1 ADAMANTANEMETHANOL DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF Daicel Chemical Industries, Ltd. (JP) 2000-04-05 EP disclosed
US-4131656-A Intermediates for 5-(tertiary alkyl) resorcinol preparation ELI LILLY AND COMPANY (US) 1978-12-26 US disclosed
US-4100170-A ANTIHYPERTENSIVE AGENTS, MONOAMINE OXIDASE INHIBITORS PENNWALT CORPORATION (US) 1978-07-11 US disclosed
US-4087410-A 5-(Tertiary alkyl) resorcinol preparation and intermediates therefor ELI LILLY AND COMPANY (US) 1978-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12240857-B2 Adamantane derivatives for the treatment of filovirus infection IFNAR1, MEP1B, MEP1A GRIN2D 3988/4885GRIN3B 2211/4885GRIN1 1774/4885
US-11377415-B2 Method for converting N,N-dialkylamide compound into ester compound using complex of fourth-period transition metal as catalyst NEK4, TENT4A, TCF4 GRIN2D 1966/4885GRIN3B 772/4885GRIN1 1999/4885
US-20210107934-A1 THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS CTDSP1, RNGTT, SSU72 GRIN2D 3969/4885GRIN3B 4274/4885GRIN1 3596/4885
US-20020016516-A1 Hydrocarbon bonded to a carbon atom which is bonded to a hydroxyl group, a methane group, and an adamantane ring; or its protected derivatives; alcohol intermediates for acrylic ester monomers for hydrophilic, adhesive photoresists ADH1A, ADGRF1, ADGRE5 GRIN2D 845/4885GRIN3B 1566/4885GRIN1 484/4885
US-20200399200-A1 METHOD FOR CONVERTING N,N-DIALKYLAMIDE COMPOUND INTO ESTER COMPOUND USING COMPLEX OF FOURTH-PERIOD TRANSITION METAL AS CATALYST NEK4, TENT4A, TCF4 GRIN2D 1966/4885GRIN3B 772/4885GRIN1 1999/4885
US-11161869-B2 Thermally-cleavable protecting and linker groups CTDSP1, RNGTT, SSU72 GRIN2D 3969/4885GRIN3B 4274/4885GRIN1 3596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.