Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18123361 | 1.00 | TSHR (0.44) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL18123366 | 0.96 | TSHR (0.53) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL18123356 | 0.96 | TSHR (0.49) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL15691896 | 0.94 | TSHR (0.50) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL20034124 | 0.91 | TSHR (0.37) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL24089170 | 0.90 | TSHR (0.43) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL19847411 | 0.90 | TSHR (0.43) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL8738485 | 0.90 | TSHR (0.36) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11513872 | 0.89 | TSHR (0.48) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL19847468 | 0.88 | TSHR (0.44) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11866590-B2 | Diisocyanate-based radical polymerizable silane coupling compound having an urethane bond | KABUSHIKI KAISHA SHOFU (JP) | 2024-01-09 | — | — | US | disclosed |
| US-11786444-B2 | Dental polyfunctional monomers and dental hydroxyl group-containing monomers | MITSUI CHEMICALS, INC. (JP) | 2023-10-17 | — | — | US | disclosed |
| US-11786444-B2 | Dental polyfunctional monomers and dental hydroxyl group-containing monomers | MITSUI CHEMICALS, INC. (JP) | 2023-10-17 | — | — | US | disclosed |
| US-20220304901-A1 | PHOTOPOLYMERIZABLE RESIN COMPOSITIONS FOR DURABLE DENTAL PROSTHETIC AND RESTORATIVE ARTICLES | DENTSPLY SIRONA INC. (US) | 2022-09-29 | — | — | US | disclosed |
| US-11311462-B2 | Adhesive monomers for dental materials | MITSUI CHEMICALS, INC. (JP) | 2022-04-26 | — | — | US | disclosed |
| US-20210395532-A1 | DIISOCYANATE-BASED RADICAL POLYMERIZABLE SILANE COUPLING COMPOUND HAVING AN URETHANE BOND | KABUSHIKI KAISHA SHOFU (JP) | 2021-12-23 | — | — | US | disclosed |
| US-20210378919-A1 | DENTAL POLYFUNCTIONAL MONOMERS AND DENTAL HYDROXYL GROUP-CONTAINING MONOMERS | MITSUI CHEMICALS, INC. (JP) | 2021-12-09 | — | — | US | disclosed |
| US-11110038-B2 | Dental polymerizable monomers, compositions, adhesive dental materials and kits | MITSUI CHEMICALS, INC. (JP) | 2021-09-07 | — | — | US | disclosed |
| US-20200030194-A1 | DENTAL POLYMERIZABLE MONOMERS, COMPOSITIONS, ADHESIVE DENTAL MATERIALS AND KITS | MITSUI CHEMICALS, INC. (JP) | 2020-01-30 | — | — | US | disclosed |
| US-10470980-B2 | Dental polymerizable monomers, compositions, adhesive dental materials and kits | MITSUI CHEMICALS, INC. (JP) | 2019-11-12 | — | — | US | disclosed |
| US-20150079379-A1 | POLYMERIZABLE COMPOSITION, POLYMER, OPTICAL ADHESIVE SHEET, IMAGE DISPLAY DEVICE, AND METHOD FOR MANUFACTURING IMAGE DISPLAY DEVICE | SHOWA DENKO K.K. (JP) | 2015-03-19 | — | — | US | disclosed |
| US-20150079379-A1 | POLYMERIZABLE COMPOSITION, POLYMER, OPTICAL ADHESIVE SHEET, IMAGE DISPLAY DEVICE, AND METHOD FOR MANUFACTURING IMAGE DISPLAY DEVICE | SHOWA DENKO K.K. (JP) | 2015-03-19 | — | — | US | disclosed |
| US-20150005406-A1 | URETHANE (METH)ACRYLATE AND MOISTURE-PROOF INSULATING COATING MATERIAL | SHOWA DENKO K.K. (JP) | 2015-01-01 | — | — | US | disclosed |
| US-20150005406-A1 | URETHANE (METH)ACRYLATE AND MOISTURE-PROOF INSULATING COATING MATERIAL | SHOWA DENKO K.K. (JP) | 2015-01-01 | — | — | US | disclosed |
| US-20140287167-A1 | POLYMERIZABLE COMPOSITION, POLYMER, IMAGE-DISPLAY DEVICE, AND MANUFACTURING METHOD THEREFOR | SHOWA DENKO K.K. (JP) | 2014-09-25 | — | — | US | disclosed |
| US-20140287167-A1 | POLYMERIZABLE COMPOSITION, POLYMER, IMAGE-DISPLAY DEVICE, AND MANUFACTURING METHOD THEREFOR | SHOWA DENKO K.K. (JP) | 2014-09-25 | — | — | US | disclosed |
| WO-2014069134-A1 | POLYMERIZABLE COMPOSITION, POLYMER, OPTICAL ADHESIVE SHEET, IMAGE DISPLAY DEVICE AND PRODUCTION METHOD FOR SAME | 昭和電工株式会社 (JP) | 2014-05-08 | — | — | WO | disclosed |
| WO-2012071329-A2 | HIGH STRENGTH DENTAL MATERIAL | DENTSPLY INTERNATIONAL INC (US) | 2012-05-31 | — | — | WO | disclosed |
| US-20120129973-A1 | HIGH STRENGTH DENTAL MATERIAL | DENTSPLY INTERNATIONAL INC (US) | 2012-05-24 | — | — | US | disclosed |
| US-20120129973-A1 | HIGH STRENGTH DENTAL MATERIAL | DENTSPLY INTERNATIONAL INC (US) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200030194-A1 | DENTAL POLYMERIZABLE MONOMERS, COMPOSITIONS, ADHESIVE DENTAL MATERIALS AND KITS | ACTN1, SMCHD1, CAPZA1 | TSHR 4160/4885ALDH1A1 302/4885TP53 4439/4885 |
| US-10470980-B2 | Dental polymerizable monomers, compositions, adhesive dental materials and kits | HRH3, HRH1, HRH2 | TSHR 861/4885ALDH1A1 394/4885TP53 3656/4885 |
| US-11786444-B2 | Dental polyfunctional monomers and dental hydroxyl group-containing monomers | PAM, CAD, FHIT | TSHR 2948/4885ALDH1A1 1173/4885TP53 2612/4885 |
| US-20210378919-A1 | DENTAL POLYFUNCTIONAL MONOMERS AND DENTAL HYDROXYL GROUP-CONTAINING MONOMERS | PAM, CAD, FHIT | TSHR 2948/4885ALDH1A1 1173/4885TP53 2612/4885 |
| US-11866590-B2 | Diisocyanate-based radical polymerizable silane coupling compound having an urethane bond | CAD, DCLRE1A, STIM1 | TSHR 4002/4885ALDH1A1 1898/4885TP53 2770/4885 |
| US-20220304901-A1 | PHOTOPOLYMERIZABLE RESIN COMPOSITIONS FOR DURABLE DENTAL PROSTHETIC AND RESTORATIVE ARTICLES | KDM3A, PSMA3, NOX3 | TSHR 4305/4885ALDH1A1 2106/4885TP53 2292/4885 |
| US-11311462-B2 | Adhesive monomers for dental materials | COL1A1, CDH1, GJA1 | TSHR 4250/4885ALDH1A1 836/4885TP53 3501/4885 |
| US-20120129973-A1 | HIGH STRENGTH DENTAL MATERIAL | SMCHD1, CAD, DSG1 | TSHR 4776/4885ALDH1A1 4268/4885TP53 3158/4885 |
| US-20210395532-A1 | DIISOCYANATE-BASED RADICAL POLYMERIZABLE SILANE COUPLING COMPOUND HAVING AN URETHANE BOND | CAD, DCLRE1A, STIM1 | TSHR 4002/4885ALDH1A1 1898/4885TP53 2770/4885 |
| US-11110038-B2 | Dental polymerizable monomers, compositions, adhesive dental materials and kits | ACTN1, SMCHD1, CAPZA1 | TSHR 4160/4885ALDH1A1 302/4885TP53 4439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.