SCHEMBL8739889

SCHEMBL8739889

CC(C)(C)c1ccc2c(c1)c1cc(C(C)(C)C)ccc1n2-c1cccc(-c2cccc(-n3c4ccc(C(C)(C)C)cc4c4cc(C(C)(C)C)ccc43)c2)c1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.42
OPRD1 P41143 5/20 0.39
NOTUM Q6P988 1/20 0.39
RXRA P19793 2/20 0.38
RXRB P28702 2/20 0.38
HTR1D P28221 1/20 0.38
PGR P06401 1/20 0.38
RORA P35398 1/20 0.38
RORC P51449 1/20 0.38
RORB Q92753 1/20 0.38
SERPINE1 P05121 1/20 0.38
OPRM1 P35372 2/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
OPRK1 P41145 1/20 0.36
KCNH2 Q12809 1/20 0.36
DNMT1 P26358 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16605612 0.95 KIF11 (0.39) KIF11OPRD1NOTUMRXRARXRB
SCHEMBL8739892 0.94 KDM4E (0.46) KIF11OPRD1NOTUMRXRARXRB
SCHEMBL8282702 0.94 KDM4E (0.46) KIF11OPRD1NOTUMRXRARXRB
SCHEMBL8739898 0.94 KDM4E (0.46) KIF11OPRD1NOTUMRXRARXRB
SCHEMBL14464646 0.92 RXRA (0.43) KIF11OPRD1NOTUMRXRARXRB
SCHEMBL25693139 0.92 ALDH1A1 (0.41) KIF11OPRD1NOTUMRXRARXRB
SCHEMBL31297416 0.91 NOTUM (0.42) KIF11OPRD1NOTUMHTR1DPGR
SCHEMBL63688 0.91 NOTUM (0.42) KIF11OPRD1NOTUMHTR1DPGR
SCHEMBL10090552 0.91 KDM4E (0.43) KIF11OPRD1NOTUMPGRRORA
SCHEMBL10090546 0.91 KCNH2 (0.43) KIF11OPRD1NOTUMRXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210001-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230210001-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-11177450-B2 Organoelectroluminescent element, and light emission device, display device, and illumination device in which said organoelectroluminescent element is used UDC IRELAND LIMITED (IE) 2021-11-16 US disclosed
US-10944061-B2 Organic electroluminescent element and compound UDC IRELAND LIMITED (IE) 2021-03-09 US disclosed
US-10243153-B2 Material for organic electroluminescence device and organic electroluminescence device UDC IRELAND LIMITED (IE) 2019-03-26 US disclosed
US-20160254462-A1 Material For Organic Electroluminescence Device And Organic Electroluminescence Device UDC IRELAND LTD (IE) 2016-09-01 US disclosed
US-20160254462-A1 Material For Organic Electroluminescence Device And Organic Electroluminescence Device UDC IRELAND LTD (IE) 2016-09-01 US disclosed
US-9340728-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2016-05-17 US disclosed
US-9340728-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2016-05-17 US disclosed
US-9318714-B2 Material for organic electroluminescence device and organic electroluminescence device UDC Ireland (IE) 2016-04-19 US disclosed
US-20120126221-A1 CHARGE-TRANSPORTING MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-05-24 US disclosed
US-20110073848-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110073848-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
WO-2011025068-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 WO disclosed
US-20110050092-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20110050092-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20110049497-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
WO-2011024733-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 WO disclosed
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE NDUFS3, NDUFS2, NDUFS4 KIF11 3639/4885OPRD1 824/4885NOTUM 4570/4885
US-20110073848-A1 ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, CYBA, EPCAM KIF11 2589/4885OPRD1 766/4885NOTUM 4371/4885
US-20120126221-A1 CHARGE-TRANSPORTING MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE SLC26A3, SLC43A3, SLCO2A1 KIF11 2743/4885OPRD1 801/4885NOTUM 3815/4885
US-10944061-B2 Organic electroluminescent element and compound POU2F2, DDT, LEF1 KIF11 4027/4885OPRD1 2021/4885NOTUM 137/4885
US-20110050092-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTROLUMINESCENCE DEVICE L1CAM, EED, CCNE2 KIF11 2375/4885OPRD1 959/4885NOTUM 4484/4885
US-20160254462-A1 Material For Organic Electroluminescence Device And Organic Electroluminescence Device VCL, L1CAM, EML4 KIF11 86/4885OPRD1 2409/4885NOTUM 1278/4885
US-10243153-B2 Material for organic electroluminescence device and organic electroluminescence device VCL, L1CAM, EML4 KIF11 86/4885OPRD1 2409/4885NOTUM 1278/4885
US-20110049497-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE VCL, L1CAM, EML4 KIF11 86/4885OPRD1 2409/4885NOTUM 1278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.