Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 4/20 | 0.40 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.39 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.39 |
| ▸ | P2RY4 known ✓ | P51582 | 1/20 | 0.39 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.38 |
| ▸ | KCNH3 | Q9ULD8 | 10/20 | 0.55 |
| ▸ | RAD51 | Q06609 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | CDK4 | P11802 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CDK7 | P50613 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 2/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCNH | P51946 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL893015 | 1.00 | KCNH3 (0.55) | KCNH3RAD51NPSR1CA2CDK1 | |
| SCHEMBL29885454 | 1.00 | KCNH3 (0.55) | KCNH3RAD51NPSR1CA2CDK1 | |
| SCHEMBL30448563 | 0.90 | KCNH3 (0.57) | KCNH3NPSR1CA2CDK1KDR | |
| SCHEMBL5632031 | 0.90 | KCNH3 (0.57) | KCNH3NPSR1CA2CDK1KDR | |
| SCHEMBL793178 | 0.90 | KCNH3 (0.57) | KCNH3NPSR1CA2CDK1KDR | |
| SCHEMBL893019 | 0.89 | KCNH3 (0.56) | KCNH3NPSR1CA2CDK1KDR | |
| SCHEMBL16671688 | 0.89 | RAD51 (0.49) | KCNH3RAD51NPSR1CA2CA1 | |
| SCHEMBL10435962 | 0.87 | RAD51 (0.47) | KCNH3RAD51NPSR1CA2CA1 | |
| SCHEMBL893765 | 0.86 | RAD51 (0.60) | RAD51NPSR1CA2CA1CA9 | |
| SCHEMBL1169584 | 0.86 | RAD51 (0.60) | RAD51NPSR1CA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275551-A1 | INCORPORATION OF DYE INTO GRANULAR LAUNDRY DETERGENT | CONOPCO, INC., D/B/A UNILEVER | 2011-11-10 | — | — | US | claimed |
| US-20110131736-A1 | SHADING COMPOSITION | CONOPCO, INC., D/B/A UNILEVER | 2011-06-09 | — | — | US | claimed |
| US-4271036-A | Colorless formulations of optical brighteners from the series of bis-triazinylamino-stilbene-disulfonic acid compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-02 | — | — | US | claimed |
| CN-110831981-B | Dual activated microgel | 路博润先进材料公司 | 2022-06-24 | — | — | CN | disclosed |
| EP-2714878-B2 | LIQUID LAUNDRY COMPOSITION | UNILEVER PLC NO 41424 (GB) | 2021-06-02 | — | — | EP | disclosed |
| EP-2591082-B1 | COMPOSITIONS COMPRISING OPTICAL BENEFIT AGENTS | UNILEVER PLC (GB) | 2020-11-18 | — | — | EP | disclosed |
| CN-110831981-A | Double activated microgel | 路博润先进材料公司 | 2020-02-21 | — | — | CN | disclosed |
| EP-1865051-B1 | Bleaching compositions | PROCTER & GAMBLE (US) | 2019-03-20 | — | — | EP | disclosed |
| EP-2900799-B1 | LAUNDRY DETERGENT PARTICLES | UNILEVER PLC (GB) | 2016-11-02 | — | — | EP | disclosed |
| US-9290725-B2 | Laundry detergent particles | CONOPCO INC. (US) | 2016-03-22 | — | — | US | disclosed |
| US-9222061-B2 | Laundry detergent particle | CONOPCO, INC. (US) | 2015-12-29 | — | — | US | disclosed |
| US-4399049-A | PARTICLES EXTRUDED WITH ETHOXYLATED NONIONIC SURFACTANT; STORAGE STABILITY; RABID DISPERSION; LAUNDERING | THE PROCTER & GAMBLE COMPANY (US) | 1983-08-16 | — | — | US | disclosed |
| US-4333862-A | Detergent compositions comprising mixture of cationic, anionic and nonionic surfactants | THE PROCTER & GAMBLE COMPANY (US) | 1982-06-08 | — | — | US | disclosed |
| EP-0051986-A2 | Detergent compositions | THE PROCTER & GAMBLE COMPANY (US) | 1982-05-19 | — | — | EP | disclosed |
| US-4321165-A | Detergent compositions comprising cationic, anionic and nonionic surfactants | THE PROCTER & GAMBLE COMPANY (US) | 1982-03-23 | — | — | US | disclosed |
| EP-0040038-A2 | Granular detergent compositions | THE PROCTER & GAMBLE COMPANY (US) | 1981-11-18 | — | — | EP | disclosed |
| EP-0034387-A2 | Mulls containing chain structure clay suspension aids | THE PROCTER & GAMBLE COMPANY (US) | 1981-08-26 | — | — | EP | disclosed |
| US-4271036-A | Colorless formulations of optical brighteners from the series of bis-triazinylamino-stilbene-disulfonic acid compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-02 | — | — | US | disclosed |
| US-4264466-A | LAUNDRY DETERGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1981-04-28 | — | — | US | disclosed |
| EP-0000224-A1 | Liquid detergent composition for improved greasy soil removal | THE PROCTER & GAMBLE COMPANY (US) | 1979-01-10 | — | — | EP | disclosed |