SCHEMBL898238

SCHEMBL898238

COc1cc(CCNC(=O)c2ccc(O)cc2O)ccc1O

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.58
OR51E2 Q9H255 1/20 0.58
DNMT3A Q9Y6K1 1/20 0.57
MTNR1A P48039 1/20 0.56
MTNR1B P49286 1/20 0.56
TYR P14679 1/20 0.54
ACHE P22303 1/20 0.54
HDAC1 Q13547 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
PTPN1 P18031 1/20 0.51
NOX4 Q9NPH5 1/20 0.51
ADORA2A P29274 1/20 0.51
ADORA2B P29275 1/20 0.51
SYK P43405 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29561675 1.00 ALOX5 (0.58) ALOX5OR51E2DNMT3AMTNR1AMTNR1B
SCHEMBL898313 0.87 PTPN7 (0.54) ALOX5OR51E2
SCHEMBL15329262 0.86 ESRRG (0.60) ALOX5OR51E2MTNR1AMTNR1BNOX4
SCHEMBL899105 0.86 PTPN7 (0.53) ALOX5OR51E2
SCHEMBL899104 0.86 PTPN7 (0.53) ALOX5OR51E2
SCHEMBL18619475 0.85 DNMT3A (0.60) DNMT3ASYK
SCHEMBL30259890 0.85 ALDH1A1 (0.65) DNMT3ASYK
SCHEMBL28306080 0.84 ALOX15 (0.67) ACHESYK
SCHEMBL31511909 0.83 MEN1 (0.67) ALOX5OR51E2PTPN1
SCHEMBL1840837 0.83 MEN1 (0.67) ALOX5OR51E2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3470464-A1 LAYER COMPOSITIONS WITH IMPROVED ELECTRICAL PARAMETERS COMPRISING PEDOT/PSS AND A STABILIZER Heraeus Deutschland GmbH & Co KG (DE) 2019-04-17 EP claimed
EP-2008530-B1 Aroma composition for reducing or suppressing unwanted bitter and astringent impressions SYMRISE AG (DE) 2011-01-19 EP claimed
US-20080317923-A1 AROMA COMPOSITION FOR REDUCING OR SUPPRESSING AN UNDESIRED BITTER, ASTRINGENT IMPRESSION SYMRISE GMBH & CO. KG (DE) 2008-12-25 US claimed
EP-2001448-A2 FLAVOR-ENHANCING COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE Cadbury Adams USA LLC (US) 2008-12-17 EP claimed
US-20080214675-A1 Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste SYMRISE GMBH & CO. KG (DE) 2008-09-04 US claimed
WO-2007089652-A2 FLAVOR-ENHANCING COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE CADBURY ADAMS USA LLC (US) 2007-08-09 WO claimed
US-20070178123-A1 FLAVOR-ENHANCING COMPOSITIONS, METHOD OF MANUFACTURE, AND METHODS OF USE KRAFT FOODS GLOBAL BRANDS LLC 2007-08-02 US claimed
US-20250163006-A1 New Coolants, and Preparations Containing Same SYMRISE AG (DE) 2025-05-22 US disclosed
US-20250066320-A1 Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same SYMRISE AG (DE) 2025-02-27 US disclosed
EP-4469439-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-12-04 EP disclosed
EP-3689324-B1 NEW COOLING AGENTS AND PREPARATIONS COMPRISING THEM SYMRISE AG (DE) 2024-11-20 EP disclosed
US-12089620-B2 Delivery system for food additives and its preparation SYMRISE AG (DE) 2024-09-17 US disclosed
US-20240000746-A1 New Cooling Agents and Preparations Containing Them SYMRISE AG (DE) 2024-01-04 US disclosed
US-20080214675-A1 Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste SYMRISE GMBH & CO. KG (DE) 2008-09-04 US disclosed
WO-2008046895-A1 SUBSTITUTED BICYCLO[4.1.0]HEPTANE-7-CARBOXYLIC ACID AMIDES AND DERIVATIVES THEREOF AS FOOD FLAVOR SUBSTANCES SYMRISE GMBH & CO. KG (DE) 2008-04-24 WO disclosed
EP-1909599-A1 USE OF HESPERETIN FOR ENHANCING THE SWEET TASTE Symrise GmbH & Co. KG (DE) 2008-04-16 EP disclosed
WO-2007107596-A1 USE OF 4-HYDROXYDIHYDROCHALCONES AND THEIR SALTS FOR ENHANCING AN IMPRESSION OF SWEETNESS SYMRISE GMBH & CO. KG (DE) 2007-09-27 WO disclosed
WO-2007089652-A2 FLAVOR-ENHANCING COMPOSITIONS, METHODS OF MANUFACTURE, AND METHODS OF USE CADBURY ADAMS USA LLC (US) 2007-08-09 WO disclosed
US-20070178123-A1 FLAVOR-ENHANCING COMPOSITIONS, METHOD OF MANUFACTURE, AND METHODS OF USE KRAFT FOODS GLOBAL BRANDS LLC 2007-08-02 US disclosed
WO-2007014879-A1 USE OF HESPERETIN FOR ENHANCING THE SWEET TASTE SYMRISE GMBH & CO. KG (DE) 2007-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250066320-A1 Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same TAS2R5, TAS2R7, TAS2R8 ALOX5 121/4885OR51E2 429/4885DNMT3A 2692/4885
US-20240000746-A1 New Cooling Agents and Preparations Containing Them TTPA, TREH, TAS2R45 ALOX5 1188/4885OR51E2 1498/4885DNMT3A 4875/4885
US-20250163006-A1 New Coolants, and Preparations Containing Same TTR, TAS2R5, TAS2R50 ALOX5 1209/4885OR51E2 964/4885DNMT3A 4780/4885
US-20080214675-A1 Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste TAS1R1, TAS2R1, TAS1R2 ALOX5 523/4885OR51E2 72/4885DNMT3A 1544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.