Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 13/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 12/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL9893732 | 0.73 | ACHE (0.42) | CYP3A4ACHEESR2CYP1A2CYP2D6 | |
| Potassium Ion SCHEMBL352089 | 0.73 | CYP1A2 (0.48) | CYP3A4HSD17B10HSD17B1HSD17B2CYP2C9 | |
| Potassium Ion SCHEMBL16506214 | 0.71 | IDO1 (0.33) | CYP1A2CYP2D6CYP2C19 | |
| Potassium Ion SCHEMBL15955814 | 0.71 | ALDH1A1 (0.41) | ALDH1A1TSHRTDP1ESR2 | |
| Potassium Ion SCHEMBL909185 | 0.71 | PRKCI (0.44) | TSHRENPP2 | |
| SCHEMBL14761696 | 0.70 | ACHE (0.44) | CYP3A4ACHEESR2CYP1A2CYP2D6 | |
| Potassium Ion SCHEMBL9893821 | 0.70 | KMO (0.52) | CA12CA2CA9HSD17B10CYP2C9 | |
| Resorcinol SCHEMBL326229 | 0.69 | CA12 (1.00) | CYP3A4ALDH1A1CA12CA2CA9 | |
| Resorcinol SCHEMBL15515 | 0.69 | — | — | |
| Potassium Ion SCHEMBL909569 | 0.69 | ALOX15 (0.47) | CYP3A4ALDH1A1CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110004023-A1 | Potassium Organotrifluoroborate Derivative and a Production Method Therefor | SNU R & DB FOUNDATION (KR) | 2011-01-06 | — | — | US | claimed |
| US-9908819-B1 | Printing method for production a ceramic green body | WZR ceramic solutions GmbH (DE) | 2018-03-06 | — | — | US | disclosed |
| US-9024071-B2 | Therapeutic compounds | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-05-05 | — | — | US | disclosed |
| US-8513465-B2 | Potassium organotrifluoroborate derivative and a production method therefor | SNU R&DB FOUNDATION (KR) | 2013-08-20 | — | — | US | disclosed |
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-20110004023-A1 | Potassium Organotrifluoroborate Derivative and a Production Method Therefor | SNU R & DB FOUNDATION (KR) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | CYP3A4 3867/4885ALDH1A1 4010/4885CA12 4835/4885 |
| US-20110004023-A1 | Potassium Organotrifluoroborate Derivative and a Production Method Therefor | CYP4F11, KCNJ11, KCNA7 | CYP3A4 112/4885ALDH1A1 1262/4885CA12 3490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.