Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A known ✓ | P04350 | 1/20 | 0.40 |
| ▸ | TUBB known ✓ | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C known ✓ | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B known ✓ | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A known ✓ | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B known ✓ | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 known ✓ | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A known ✓ | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 known ✓ | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E known ✓ | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A known ✓ | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C known ✓ | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 known ✓ | Q9BUF5 | 1/20 | 0.40 |
| ▸ | TUBB2B known ✓ | Q9BVA1 | 1/20 | 0.40 |
| ▸ | TUBB1 known ✓ | Q9H4B7 | 1/20 | 0.40 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrazine SCHEMBL9105851 | 0.93 | KDM4E (0.41) | SIGMAR1KDM4ECYP2C9HPGDDUSP3 | |
| SCHEMBL31243458 | 0.83 | SIGMAR1 (0.46) | SIGMAR1P2RX4SMPD1TDP1PIM1 | |
| SCHEMBL31243457 | 0.83 | SIGMAR1 (0.46) | SIGMAR1HPGDP2RX4SMPD1TDP1 | |
| SCHEMBL182696 | 0.83 | SIGMAR1 (0.46) | SIGMAR1HPGDP2RX4SMPD1TDP1 | |
| SCHEMBL9106500 | 0.81 | SIGMAR1 (0.45) | SIGMAR1HPGDP2RX4SMPD1TDP1 | |
| SCHEMBL48846 | 0.78 | KDM4E (0.62) | SIGMAR1KDM4ECYP2C9HPGDDUSP3 | |
| SCHEMBL31461254 | 0.78 | HDAC3 (0.45) | SIGMAR1HPGDP2RX4SMPD1TDP1 | |
| SCHEMBL30611012 | 0.78 | KDM4E (0.62) | SIGMAR1KDM4ECYP2C9HPGDDUSP3 | |
| SCHEMBL183103 | 0.78 | HDAC3 (0.45) | SIGMAR1HPGDP2RX4SMPD1TDP1 | |
| Lithium Ion SCHEMBL18104080 | 0.75 | KDM4E (0.59) | SIGMAR1KDM4ECYP2C9HPGDDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119137239-A | Electrochromic device and composition including anode component anions | 维特罗平板玻璃有限责任公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-119072535-A | Electrochromic device comprising a polymer having residues of ((meth) acrylate-amine cationic bis (substituted-sulfonyl) imine anions)) monomers | 维特罗平板玻璃有限责任公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-119072536-A | Electrochromic device and composition comprising poly ((diallyldimethylammonium bis (substituted-sulfonyl) imide anion)) | 维特罗平板玻璃有限责任公司 | 2024-12-03 | — | — | CN | disclosed |
| US-8192948-B1 | Chemifluorescent substrate for peroxide and peroxidase detection | PIERCE BIOTECHNOLOGY, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| EP-0361470-B1 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO KK (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5171668-A | Measuring light emitted from contacting (iso)luminol, peroxide, peroxidase activity enhancer, such as indoanilines, phenolindophenol and N-methylphenothiazine, with labeled peroxidase antibody-antigen complex | FUJIREBIO INC. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0361470-A2 | Method for the chemiluminescence assay of the activity of peroxidase | FUJIREBIO INC. (JP) | 1990-04-04 | — | — | EP | disclosed |