Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | GMNN | O75496 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | THPO | P40225 | 1/20 | 0.67 |
| ▸ | HBB | P68871 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.52 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3385778 | 0.96 | TSHR (0.63) | ALDH1A1TSHRGMNNLMNATP53 | |
| SCHEMBL3386062 | 0.96 | TSHR (0.63) | ALDH1A1TSHRGMNNLMNATP53 | |
| SCHEMBL2289785 | 0.96 | TSHR (0.63) | ALDH1A1TSHRGMNNLMNATP53 | |
| SCHEMBL921255 | 0.96 | TSHR (0.63) | ALDH1A1TSHRGMNNLMNATP53 | |
| SCHEMBL14974551 | 0.92 | ALDH1A1 (0.58) | ALDH1A1TSHRGMNNLMNATP53 | |
| Eprodisate SCHEMBL293813 | 0.92 | ALDH1A1 (0.67) | ALDH1A1TSHRGMNNLMNATP53 | |
| Lithium Ion SCHEMBL28490449 | 0.92 | ALDH1A1 (0.58) | ALDH1A1TSHRGMNNLMNATP53 | |
| SCHEMBL2288142 | 0.92 | ALDH1A1 (0.58) | ALDH1A1TSHRGMNNLMNATP53 | |
| Potassium Ion SCHEMBL28472448 | 0.92 | ALDH1A1 (0.58) | ALDH1A1TSHRGMNNLMNATP53 | |
| Potassium Ion SCHEMBL10537906 | 0.89 | GMNN (0.55) | ALDH1A1TSHRGMNNLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116408051-B | Sulfonic acid anion hybridization porous material, preparation method and ethylene-ethane separation method | 中国石油天然气股份有限公司 | 2025-01-21 | — | — | CN | claimed |
| CN-113881725-B | Method for preparing 1, 4-butanedisulfonic acid ademetionine salt by electrodialysis | 江西兄弟医药有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-116864647-A | Lithium battery negative electrode material and preparation method thereof | 江西德沅新能源科技有限公司 | 2023-10-10 | — | — | CN | claimed |
| CN-116829534-A | Preparation method of 1, 4-butanedisulfonic acid | 浙江海正药业股份有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-116408051-A | Sulfonic acid anion hybridization porous material, preparation method and ethylene-ethane separation method | 中国石油天然气股份有限公司 | 2023-07-11 | — | — | CN | claimed |
| WO-2023123170-A1 | PREPARATION METHOD FOR 1,4-BUTANEDISULFONIC ACID | 浙江海正药业股份有限公司 | 2023-07-06 | — | — | WO | claimed |
| WO-2023115524-A1 | METHOD FOR PREPARING 1,4-BUTANEDISULFONIC ACID SODIUM SALT | 浙江海正药业股份有限公司 | 2023-06-29 | — | — | WO | claimed |
| CN-113262641-B | Anti-pollution reverse osmosis membrane and preparation method and application thereof | 蓝星（杭州）膜工业有限公司 | 2021-12-10 | — | — | CN | claimed |
| CN-113444757-A | Preparation method of 1, 4-butanedisulfonic acid adenosine methionine | 贵州卡本嘉泰生物科技产业发展有限公司 | 2021-09-28 | — | — | CN | claimed |
| CN-113416156-A | Preparation method of 1, 4-butanedisulfonic acid sodium salt | 深圳市铭泉盛催化剂有限公司 | 2021-09-21 | — | — | CN | claimed |
| CN-113262641-A | Anti-pollution reverse osmosis membrane and preparation method and application thereof | 蓝星（杭州）膜工业有限公司 | 2021-08-17 | — | — | CN | claimed |
| CN-109852157-B | High-hardness AR coating liquid and preparation method thereof | 东莞南玻太阳能玻璃有限公司 | 2021-06-18 | — | — | CN | claimed |
| US-20080027097-A1 | PHARMACEUTICAL DRUG CANDIDATES AND METHODS FOR PREPARATION THEREOF | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2008-01-31 | — | — | US | claimed |
| US-7253306-B2 | Pharmaceutical drug candidates and methods for preparation thereof | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2007-08-07 | — | — | US | claimed |
| EP-1646659-A2 | IMPROVED PHARMACEUTICAL DRUG CANDIDATES AND METHODS FOR PREPARATION THEREOF | Neurochem (International) Limited (CH) | 2006-04-19 | — | — | EP | claimed |
| US-20050143462-A1 | Pharmaceutical drug candidates and methods for preparation thereof | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2005-06-30 | — | — | US | claimed |
| WO-2004113391-A2 | IMPROVED PHARMACEUTICAL DRUG CANDIDATES AND METHODS FOR PREPARATION THEREOF | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2004-12-29 | — | — | WO | claimed |
| US-20250388008-A1 | FLAME RESISTANT COMPOSITE FABRIC | BROOKWOOD COMPANIES INCORPORATED (US) | 2025-12-25 | — | — | US | disclosed |
| EP-0162323-B1 | STABLE SULPHO-ADENOSYL-L-METHIONINE (SAME) SALTS, PARTICULARLY SUITABLE FOR PARENTERAL USE | BIORESEARCH S.p.A. (IT) | 1989-03-08 | — | — | EP | disclosed |
| EP-0162323-A1 | Stable sulpho-adenosyl-l-methionine (same) salts, particularly suitable for parenteral use | BIORESEARCH S.p.A. (IT) | 1985-11-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388008-A1 | FLAME RESISTANT COMPOSITE FABRIC | FAU, PFAS, FLNB | ALDH1A1 1163/4885TSHR 69/4885GMNN 1383/4885 |
| US-20050143462-A1 | Pharmaceutical drug candidates and methods for preparation thereof | MPST, TTR, STS | ALDH1A1 78/4885TSHR 4762/4885GMNN 1977/4885 |
| US-20080027097-A1 | PHARMACEUTICAL DRUG CANDIDATES AND METHODS FOR PREPARATION THEREOF | MPST, TTR, STS | ALDH1A1 78/4885TSHR 4762/4885GMNN 1977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.