Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MARK3 | P27448 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301963 | 0.77 | ALDH1A1 (0.36) | HPGDMEN1USP2ALDH1A1LMNA | |
| SCHEMBL9302110 | 0.69 | ACHE (0.35) | HTR6HRH4PDE5AHRH1HRH2 | |
| SCHEMBL9302877 | 0.68 | GRM5 (0.39) | HPGDSMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL9302233 | 0.67 | ALDH1A1 (0.39) | HTR6HPGDMEN1USP2ALDH1A1 | |
| SCHEMBL9303411 | 0.67 | ALDH1A1 (0.41) | HPGDMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL9302194 | 0.67 | ACHE (0.39) | HTR6IKBKBAURKACHUKMAPK13 | |
| SCHEMBL9302209 | 0.66 | PIK3CD (0.35) | HPGDSMN1; SMN2HRH3MEN1USP2 | |
| SCHEMBL29634202 | 0.64 | TSHR (0.33) | USP2ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6796311 | 0.64 | ALDH1A1 (0.41) | HRH4MEN1USP2ALDH1A1LMNA | |
| SCHEMBL9302522 | 0.63 | SIRT6 (0.47) | HTR6HRH4PDE5ANOD2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283248-A | Bactericides, enzyme inhibitor of DNA-gyrase in bacteria | HOFFMANN-LA ROCHE INC. (US) | 1994-02-01 | — | — | US | disclosed |