SCHEMBL936700

SCHEMBL936700

NCc1cn(Cc2ccccc2)nn1

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 11/20 0.66
NPC1 O15118 1/20 0.62
RAB9A P51151 1/20 0.62
HRH4 Q9H3N8 1/20 0.57
HSP90AB1 P08238 2/20 0.56
MAOA P21397 2/20 0.54
NOTUM Q6P988 1/20 0.54
KCNMA1 Q12791 1/20 0.51
MAOB P27338 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15795458 0.86 CYP19A1 (0.71) CYP19A1NPC1RAB9AHRH4HSP90AB1
Imidazole SCHEMBL28221370 0.85 CYP19A1 (0.50) CYP19A1NPC1RAB9AHRH4HSP90AB1
SCHEMBL28220729 0.85 CYP19A1 (0.70) CYP19A1NPC1RAB9AHRH4HSP90AB1
SCHEMBL12022159 0.84 KCNMA1 (0.69) CYP19A1NPC1RAB9AHRH4HSP90AB1
SCHEMBL3103838 0.84 CYP19A1 (0.68) CYP19A1NPC1RAB9AHRH4HSP90AB1
SCHEMBL15803296 0.83 CYP19A1 (0.56) CYP19A1NPC1RAB9AHSP90AB1NOTUM
SCHEMBL27777026 0.83 GBA1 (0.57) CYP19A1NPC1RAB9AHRH4MAOA
SCHEMBL13702605 0.83 TUBB4A (0.58) CYP19A1NPC1RAB9AHSP90AB1
SCHEMBL28221634 0.83 CYP19A1 (0.60) CYP19A1NPC1RAB9AHRH4HSP90AB1
SCHEMBL2502451 0.82 CYP19A1 (0.66) CYP19A1NPC1RAB9AHRH4HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112552490-B Nucleic acid grafted semiconductor polymer, nucleic acid probe, and preparation method and application thereof 南方科技大学 2023-04-14 CN claimed
US-20210324197-A1 SOLID COLOR FILM, PREPARATION METHOD THEREOF, AND DISPLAY DEVICE TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2021-10-21 US claimed
CN-112552490-A Nucleic acid grafted semiconductor polymer, nucleic acid probe, and preparation method and application thereof 南方科技大学 2021-03-26 CN claimed
CN-111183144-A Click-based connection 贝瑟克里科有限公司 2020-05-19 CN claimed
CN-110294725-A A kind of derivative and its process for catalytic synthesis of sponge furanone 广东医科大学 2019-10-01 CN claimed
CN-110183378-A A kind of derivative and its process for catalytic synthesis of niacinamide 广东医科大学 2019-08-30 CN claimed
CN-105324116-B Adjust the multivalence interaction with the biopolymer of polyproline bracket 新加坡科技研究局 2019-03-29 CN claimed
CN-105324116-A Tailoring multivalent interactions of biopolymers with a polyproline scaffol AGENCY SCIENCE TECH & RES 2016-02-10 CN claimed
US-20260023080-A1 METHOD FOR PROTEOME-WIDE DISCOVERY OF COVALENT LIGANDS AND COMPOSITIONS THEREOF BRIDGENE BIOSCIENCES INC (US) 2026-01-22 US disclosed
US-20250367371-A1 HYBRID BIOELECTRONIC/ENGINEERED CELL IMPLANTABLE SYSTEM FOR THERAPEUTIC AGENTS DELIVERY AND APPLICATIONS THEREOF UNIV NORTHWESTERN (US) 2025-12-04 US disclosed
US-20250313544-A1 INHIBITORS OF GLUTATHIONE S-TRANSFERASE ZETA 1 (GSTZ1) AND METHODS OF USE H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. 2025-10-09 US disclosed
US-12371461-B2 Nemo coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2025-07-29 US disclosed
WO-2025137293-A2 ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS Roche Sequencing Solutions, Inc. (US) 2025-06-26 WO disclosed
WO-2025091023-A1 ENGINEERED CELL TRANSFECTED BY ALL-IN-ONE VECTOR FOR THERAPEUTIC AGENTS PRODUCTION AND DELIVERY AND APPLICATIONS THEREOF NORTHWESTERN UNIVERSITY (US) 2025-05-01 WO disclosed
US-20100254943-A1 AMINO ACID SUBSTITUTED MOLECULES ALLOZYNE, INC. (US) 2010-10-07 US disclosed
US-20080200641-A1 AMINO ACID SUBSTITUTED MOLECULES ALLOZYNE, INC. (US) 2008-08-21 US disclosed
CN-101223272-A Expanding the eukaryotic genetic code SCRIPPS RESEARCH INST (US) 2008-07-16 CN disclosed
US-20080096819-A1 Amino acid substituted molecules ALLOZYNE, INC. (US) 2008-04-24 US disclosed
CN-101160525-A Genetic code increase of non-natural active amino acid SCRIPPS RESEARCH INST (US) 2008-04-09 CN disclosed
CN-101151366-A Proteins incorporating alkynyl amino acids into eubacteria in vivo SCRIPPS RESEARCH INST (US) 2008-03-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371461-B2 Nemo coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH CYP19A1 3378/4885NPC1 503/4885RAB9A 4061/4885
US-20210324197-A1 SOLID COLOR FILM, PREPARATION METHOD THEREOF, AND DISPLAY DEVICE ADAR, ADA, ACHE CYP19A1 1137/4885NPC1 3931/4885RAB9A 757/4885
US-20080096819-A1 Amino acid substituted molecules BCAT2, DNPEP, PTMS CYP19A1 3595/4885NPC1 3938/4885RAB9A 3608/4885
US-20100254943-A1 AMINO ACID SUBSTITUTED MOLECULES BCAT2, DNPEP, PTMS CYP19A1 3595/4885NPC1 3938/4885RAB9A 3608/4885
US-20080200641-A1 AMINO ACID SUBSTITUTED MOLECULES BCAT2, DNPEP, PTMS CYP19A1 3595/4885NPC1 3938/4885RAB9A 3608/4885
US-20260023080-A1 METHOD FOR PROTEOME-WIDE DISCOVERY OF COVALENT LIGANDS AND COMPOSITIONS THEREOF SRMS, PTMS, CHAMP1 CYP19A1 4024/4885NPC1 3261/4885RAB9A 2452/4885
US-20250313544-A1 INHIBITORS OF GLUTATHIONE S-TRANSFERASE ZETA 1 (GSTZ1) AND METHODS OF USE GSTK1, GSTM1, GSTM2 CYP19A1 1632/4885NPC1 1795/4885RAB9A 2570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.