Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11921702 | 0.76 | PPARG (0.36) | PPARGSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL1244261 | 0.72 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL6070232 | 0.72 | SMN1; SMN2 (0.51) | SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6258640 | 0.63 | SMN1; SMN2 (0.46) | PPARGSMN1; SMN2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL689620 | 0.62 | FOLH1 (0.42) | SMN1; SMN2KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL15019918 | 0.61 | PTPN1 (0.38) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL1258872 | 0.61 | CYP1A2 (0.50) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1258869 | 0.61 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL1722086 | 0.61 | TRPA1 (0.35) | KDM4E | |
| SCHEMBL657769 | 0.61 | TYR (0.33) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4285888-A1 | COMPOSITE MATERIAL HAVING REDUCED POROSITY AND A PROCESS FOR PRODUCING THEREOF | DENTSPLY DETREY GmbH (DE) | 2023-12-06 | — | — | EP | claimed |
| US-6126922-A | DENTISTRY; ANHYDROUS MIXTURES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-10-03 | — | — | US | claimed |
| EP-0975306-A1 | DENTAL COMPOSITIONS WITH IMPROVED HANDLING CAPABILITIES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-02-02 | — | — | EP | claimed |
| WO-1998046197-A1 | DENTAL COMPOSITIONS WITH IMPROVED HANDLING CAPABILITIES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-10-22 | — | — | WO | claimed |
| US-12023392-B2 | Additive manufacturing process | DENTSPLY SIRONA INC. (US) | 2024-07-02 | — | — | US | disclosed |
| US-20240180791-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2024-06-06 | — | — | US | disclosed |
| US-11931432-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-11925697-B2 | Dental impression material | DENTSPLY SIRONA INC. (US) | 2024-03-12 | — | — | US | disclosed |
| US-11918664-B2 | Direct dental filling compositions | DENTSPLY SIRONA INC. (US) | 2024-03-05 | — | — | US | disclosed |
| US-11904030-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2024-02-20 | — | — | US | disclosed |
| US-11883510-B2 | Dental composition comprising a particulate carrier supporting a coinitiator | DENTSPLY SIRONA INC. (US) | 2024-01-30 | — | — | US | disclosed |
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DENTSPLY SIRONA INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-5922786-A | PART A COMPRISES AN ACIDIC POLYMERIZABLE COMPOUND AND POLYMERIZABLE DILUENT SELECTED SO THAT IF WATER IS PRESENT, THE PH OF PART A IS GREATER THAN 2; PART B COMPRISES AN ACIDIC MATERIAL SUCH THAT THE PH IS 2; NO ETCHING STEP NEEDED | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-07-13 | — | — | US | disclosed |
| WO-1999003444-A1 | DENTAL RESIN CEMENTS HAVING IMPROVED HANDLING PROPERTIES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-01-28 | — | — | WO | disclosed |
| EP-0873107-A1 | FLUORIDE-RELEASING COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-10-28 | — | — | EP | disclosed |
| EP-0873106-A1 | USE OF METALLOFLUOROCOMPLEXES FOR DENTAL COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-10-28 | — | — | EP | disclosed |
| WO-1998046198-A1 | DENTAL PRIMER COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998046197-A1 | DENTAL COMPOSITIONS WITH IMPROVED HANDLING CAPABILITIES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1997018792-A1 | FLUORIDE-RELEASING COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-05-29 | — | — | WO | disclosed |
| WO-1997018791-A1 | USE OF METALLOFLUOROCOMPLEXES FOR DENTAL COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240180791-A1 | DENTAL COMPOSITION | CAD, MTR, ESD | PPARG 1878/4885SMN1; SMN2 4696/4885KDM4E 2703/4885 |
| US-11925697-B2 | Dental impression material | FHIT, PASK, TAS2R40 | PPARG 858/4885SMN1; SMN2 2432/4885KDM4E 1222/4885 |
| US-11904030-B2 | Dental composition | CBR3, CBR1, PRDX3 | PPARG 674/4885SMN1; SMN2 4840/4885KDM4E 3251/4885 |
| US-11931432-B2 | Dental composition | CAD, MTR, ESD | PPARG 1878/4885SMN1; SMN2 4696/4885KDM4E 2703/4885 |
| US-12023392-B2 | Additive manufacturing process | FLNA, FLNB, SAMM50 | PPARG 4595/4885SMN1; SMN2 852/4885KDM4E 4230/4885 |
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DHX35, DHX30, FLNA | PPARG 3910/4885SMN1; SMN2 4657/4885KDM4E 2344/4885 |
| US-11883510-B2 | Dental composition comprising a particulate carrier supporting a coinitiator | PICALM, PDS5B, CLTA | PPARG 2026/4885SMN1; SMN2 4169/4885KDM4E 3569/4885 |
| US-11918664-B2 | Direct dental filling compositions | CAD, DOCK5, ITGA5 | PPARG 779/4885SMN1; SMN2 2616/4885KDM4E 1578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.