Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 8/20 | 0.42 |
| ▸ | CA1 known ✓ | P00915 | 8/20 | 0.42 |
| ▸ | CA2 known ✓ | P00918 | 8/20 | 0.42 |
| ▸ | CA4 known ✓ | P22748 | 3/20 | 0.36 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 8/20 | 0.42 |
| ▸ | CA7 | P43166 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4355604 | 0.97 | CA12 (0.42) | CA12CA1CA2CA9CA7 | |
| SCHEMBL3919025 | 0.87 | CA12 (0.40) | CA12CA1CA2CA9CA7 | |
| SCHEMBL4131884 | 0.86 | ALDH1A1 (0.47) | CA12CA1CA2CA9CA7 | |
| SCHEMBL4868644 | 0.83 | TDP1 (0.46) | CA12CA1CA2CA9CA7 | |
| SCHEMBL4355608 | 0.82 | TDP1 (0.44) | CA12CA1CA2CA9CA7 | |
| SCHEMBL939926 | 0.82 | TDP1 (0.44) | CA12CA1CA2CA9CA7 | |
| SCHEMBL419937 | 0.82 | THRB (0.41) | ALDH1A1MAPK1MAPTHTTTHRB | |
| SCHEMBL2514267 | 0.81 | CA2 (0.47) | CA12CA1CA2CA9CA7 | |
| SCHEMBL4866300 | 0.81 | CA12 (0.41) | CA12CA1CA2CA9CA7 | |
| SCHEMBL24593452 | 0.79 | CA12 (0.39) | CA12CA1CA2CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7866806-B2 | Liquid-composition set, and liquid-applying method and liquid-applying apparatus employing the set | CANON KABUSHIKI KAISHA (JP) | 2011-01-11 | — | — | US | claimed |
| US-7866806-B2 | Liquid-composition set, and liquid-applying method and liquid-applying apparatus employing the set | CANON KABUSHIKI KAISHA (JP) | 2011-01-11 | — | — | US | disclosed |
| US-7538147-B2 | Image forming method, pattern forming method and liquid-applying apparatus which make use of liquid compositions | CANON KABUSHIKI KAISHA (JP) | 2009-05-26 | — | — | US | disclosed |
| US-20060221117-A1 | Image forming method, pattern forming method and liquid-applying apparatus which make use of liquid compositions | CANON KABUSHIKI KAISHA (JP) | 2006-10-05 | — | — | US | disclosed |
| US-20060146087-A1 | Liquid, ph-sensitive ink, method and apparatus using the same | CANON KABUSHIKI KAISHA (JP) | 2006-07-06 | — | — | US | disclosed |
| WO-2005085370-A1 | IMAGE FORMING METHOD, PATTERN FORMING METHOD AND LIQUID-APPLYING APPARATUS WHICH MAKE USE OF LIQUID COMPOSITIONS | CANON KABUSHIKI KAISHA (JP) | 2005-09-15 | — | — | WO | disclosed |
| WO-2004106440-A1 | LIQUID, PH-SENSITIVE INK, METHOD AND APPARATUS USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2004-12-09 | — | — | WO | disclosed |