Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phenolphthalein. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS known ✓ | P04818 | 1/20 | 0.70 |
| ▸ | ESR2 known ✓ | Q92731 | 1/20 | 0.70 |
| ▸ | CFTR | P13569 | 1/20 | 0.73 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | POLB | P06746 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.70 |
| ▸ | ESR1 | P03372 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886398 | 0.85 | CFTR (1.00) | CFTRGOPCLMNATDP1MAPT | |
| Phenolphthalein SCHEMBL28196770 | 0.83 | MAPT (0.93) | CFTRGOPCLMNATDP1MAPT | |
| SCHEMBL822834 | 0.82 | CFTR (0.73) | CFTRGOPCLMNATDP1MAPT | |
| Phenolphthalein SCHEMBL29362413 | 0.82 | MAPT (1.00) | CFTRGOPCLMNATDP1MAPT | |
| SCHEMBL19021292 | 0.82 | CFTR (0.73) | CFTRGOPCLMNATDP1MAPT | |
| Phenolphthalein SCHEMBL27670 | 0.82 | MAPT (1.00) | CFTRGOPCLMNATDP1MAPT | |
| Phenolphthalein SCHEMBL6139696 | 0.82 | MAPT (1.00) | CFTRGOPCLMNATDP1MAPT | |
| SCHEMBL9320712 | 0.82 | POLB (1.00) | CFTRGOPCLMNATDP1MAPT | |
| SCHEMBL14157903 | 0.81 | CFTR (0.67) | CFTRGOPCLMNATDP1MAPT | |
| Phenolphthalein SCHEMBL4970409 | 0.81 | MAPT (0.82) | CFTRGOPCLMNATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102417499-A | Preparation method of phenolphthalein complexing agent | TIANJIN CHEM REAGENT RES INST | 2012-04-18 | — | — | CN | claimed |
| US-12461084-B2 | Soil analysis apparatus | Klonec Automation Systems Pvt. Ltd. (IN) | 2025-11-04 | — | — | US | disclosed |
| CN-117949441-A | Mammal urine detection product, mammal urine detection system and application thereof | 上海能有生物科技有限公司 | 2024-04-30 | — | — | CN | disclosed |
| EP-3685139-B1 | REACTIVE DEMARCATION TEMPLATE AND METHOD FOR HAZARDOUS CONTAMINANT TESTING | BECTON DICKINSON CO (US) | 2023-12-13 | — | — | EP | disclosed |
| US-20230088751-A1 | A SOIL ANALYSIS APPARATUS | Klonec Automation Systems Pvt. Ltd. (IN) | 2023-03-23 | — | — | US | disclosed |
| US-11385183-B2 | Method for detecting copper(II) ions using a hydrazone-based colorimetric sensor | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2022-07-12 | — | — | US | disclosed |
| US-11360001-B2 | Reactive demarcation template for hazardous contaminant testing | BECTON, DICKINSON AND COMPANY (US) | 2022-06-14 | — | — | US | disclosed |
| US-20210109027-A1 | METHOD FOR DETECTING COPPER(II) IONS USING A HYDRAZONE-BASED COLORIMETRIC SENSOR | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2021-04-15 | — | — | US | disclosed |
| WO-2021028942-A1 | A SOIL ANALYSIS APPARATUS | KLONEC AUTOMATION SYSTEMS PRIVATE LIMITED (IN) | 2021-02-18 | — | — | WO | disclosed |
| EP-3685139-A1 | REACTIVE DEMARCATION TEMPLATE FOR HAZARDOUS CONTAMINANT TESTING | Becton, Dickinson and Company (US) | 2020-07-29 | — | — | EP | disclosed |
| CN-102417499-A | Preparation method of phenolphthalein complexing agent | TIANJIN CHEM REAGENT RES INST | 2012-04-18 | — | — | CN | disclosed |
| CN-102417499-A | Preparation method of phenolphthalein complexing agent | TIANJIN CHEM REAGENT RES INST | 2012-04-18 | — | — | CN | disclosed |
| WO-2011113436-A1 | A method for promotion of hemostasis and/or wound healing | Ferrosan Medical Devices A/S (DK) | 2011-09-22 | — | — | WO | disclosed |
| CN-102014973-A | Device for promotion of hemostasis and/or wound healing | FERROSAN AS (DK) | 2011-04-13 | — | — | CN | disclosed |
| US-20110021964-A1 | Device for Promotion of Hemostasis and/or Wound Healing | Ferrosan Medical Devices A/S (DK) | 2011-01-27 | — | — | US | disclosed |
| EP-2259803-A2 | DEVICE FOR PROMOTION OF HEMOSTASIS AND/OR WOUND HEALING | Ferrosan Medical Devices A/S (DK) | 2010-12-15 | — | — | EP | disclosed |
| US-20090286579-A1 | Intelligent Wireless Device Indicator | EMBARQ HOLDINGS COMPANY, LLC | 2009-11-19 | — | — | US | disclosed |
| WO-2009109194-A2 | DEVICE FOR PROMOTION OF HEMOSTASIS AND/OR WOUND HEALING | FERROSAN A/S (DK) | 2009-09-11 | — | — | WO | disclosed |
| CN-1186410-C | Hydrolytic blackboard-writing ink composition | FAN YUANHUA (CN) | 2005-01-26 | — | — | CN | disclosed |
| CN-1448448-A | Hydrolytic blackboard-writing ink composition | FAN YUANHUA (CN) | 2003-10-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11385183-B2 | Method for detecting copper(II) ions using a hydrazone-based colorimetric sensor | FTH1, GGH, FECH | TYMS 4445/4885ESR2 2514/4885CFTR 3282/4885 |
| US-20210109027-A1 | METHOD FOR DETECTING COPPER(II) IONS USING A HYDRAZONE-BASED COLORIMETRIC SENSOR | FTH1, GGH, FECH | TYMS 4445/4885ESR2 2514/4885CFTR 3282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.