SCHEMBL95140

SCHEMBL95140

CC(C)(N)Cc1ncccc1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
HSD17B10 Q99714 2/20 0.46
KDM4E B2RXH2 5/20 0.46
CHRM1 P11229 2/20 0.46
CHRM2 P08172 1/20 0.46
CHRM4 P08173 1/20 0.46
CHRM5 P08912 1/20 0.46
CHRM3 P20309 1/20 0.46
CYP2C19 P33261 1/20 0.44
HIF1A Q16665 1/20 0.44
KMT2A Q03164 1/20 0.40
SLC6A2 P23975 3/20 0.39
TAAR1 Q96RJ0 1/20 0.39
COMT P21964 2/20 0.37
MMP2 P08253 1/20 0.37
TSHR P16473 1/20 0.37
ADRA1A P35348 1/20 0.37
METAP2 P50579 1/20 0.37
METAP1 P53582 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12870191 0.85 ALDH1A1 (0.59) ALDH1A1L3MBTL1HSD17B10KDM4ECHRM1
SCHEMBL19214826 0.79 NOS3 (0.45) ALDH1A1L3MBTL1KDM4ESLC6A2TAAR1
SCHEMBL7000461 0.77 L3MBTL1 (0.59) ALDH1A1L3MBTL1HSD17B10KDM4ECHRM1
SCHEMBL4212829 0.74
SCHEMBL29468017 0.74
SCHEMBL765054 0.74
SCHEMBL31121578 0.74
SCHEMBL30463155 0.71
SCHEMBL1179397 0.71
SCHEMBL29834150 0.71 KDM4E (0.43) ALDH1A1L3MBTL1HSD17B10KDM4ECHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023054558-A1 COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT KAO CORPORATION (JP) 2023-04-06 WO claimed
EP-4159184-A1 COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT Kao Corporation (JP) 2023-04-05 EP claimed
EP-2658508-B2 TWO-PART HAIR COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2024-06-19 EP disclosed
EP-3427720-B1 AQUEOUS BLEACHING AND/OR DYEING COMPOSITION FOR KERATIN FIBERS, PROCESS, KIT AND USE THEREOF KAO GERMANY GMBH (DE) 2024-05-22 EP disclosed
EP-3427719-B1 AQUEOUS BLEACHING AND DYEING COMPOSITION FOR KERATIN FIBERS, PROCESS, KIT AND USE THEREOF KAO GERMANY GMBH (DE) 2024-03-06 EP disclosed
EP-2658513-B2 HAIR COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2023-11-29 EP disclosed
EP-4051228-B1 TWO-PART OXIDATIVE DYEING COMPOSITION KAO CORP (JP) 2023-11-22 EP disclosed
WO-2023161423-A1 DYEING COMPOSITION IN AQUEOUS-ALCOHOLIC MEDIUM KAO CORPORATION (JP) 2023-08-31 WO disclosed
US-11737959-B2 Two-part oxidative dyeing composition KAO CORPORATION (JP) 2023-08-29 US disclosed
EP-3485943-B1 PROCESS AND KIT FOR ALTERING COLOUR OF HAIR KAO GERMANY GMBH (DE) 2023-06-14 EP disclosed
EP-3346978-B1 PROCESS FOR TREATING HAIR KAO GERMANY GMBH (DE) 2023-06-14 EP disclosed
US-20060174424-A1 Composition for dyeing human hair KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2006-08-10 US disclosed
EP-1676605-A1 Product for hair dyeing KPSS-Kao Professional Salon Services GmbH (DE) 2006-07-05 EP disclosed
EP-1645264-A1 Product for hair dyeing in a two chamber aerosol can KPSS-Kao Professional Salon Services GmbH (DE) 2006-04-12 EP disclosed
EP-1632218-A1 Composition for dyeing keratin fibres KPSS-Kao Professional Salon Services GmbH (DE) 2006-03-08 EP disclosed
EP-1627666-A1 Composition for dyeing keratin fibres KPSS-Kao Professional Salon Services GmbH (DE) 2006-02-22 EP disclosed
US-20050257334-A1 Composition for dyeing keratin fibers KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2005-11-24 US disclosed
US-20050257331-A1 Composition for dyeing of keratin fibres KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2005-11-24 US disclosed
EP-1598052-A1 Composition for bleaching and dyeing keratin fibres KPSS-Kao Professional Salon Services GmbH (DE) 2005-11-23 EP disclosed
EP-1559403-A1 Composition for dyeing human hair KPSS-Kao Professional Salon Services GmbH (DE) 2005-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060174424-A1 Composition for dyeing human hair CYB5R3, MT-ND5, COX5A ALDH1A1 135/4885L3MBTL1 4497/4885HSD17B10 151/4885
US-20050257331-A1 Composition for dyeing of keratin fibres KRT18, KCNH3, MT-CO3 ALDH1A1 1967/4885L3MBTL1 4160/4885HSD17B10 1457/4885
US-11737959-B2 Two-part oxidative dyeing composition XDH, LPO, DUOX2 ALDH1A1 302/4885L3MBTL1 3852/4885HSD17B10 104/4885
US-20050257334-A1 Composition for dyeing keratin fibers KRT18, H1-5, CYB5R3 ALDH1A1 1214/4885L3MBTL1 4229/4885HSD17B10 1219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.