SCHEMBL955644

SCHEMBL955644

COc1cc(C)c(OC)c2c1OCO2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.58
ALOX15 P16050 1/20 0.58
POLB P06746 3/20 0.46
ALDH1A1 P00352 2/20 0.42
ACHE P22303 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
GSK3B P49841 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ATR Q13535 1/20 0.39
OPRK1 P41145 1/20 0.38
HTT P42858 1/20 0.38
RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29936543 1.00 CYP3A4 (0.58) CYP3A4ALOX15POLBALDH1A1ACHE
SCHEMBL15988655 0.89 CYP3A4 (0.46) CYP3A4ALOX15POLBALDH1A1ACHE
SCHEMBL4943745 0.85 CYP3A4 (0.50) CYP3A4ALOX15POLBALDH1A1ACHE
SCHEMBL13473554 0.84 CYP3A4 (0.62) CYP3A4ALOX15POLBALDH1A1ACHE
SCHEMBL12145090 0.82 CYP3A4 (0.47) CYP3A4ALOX15POLBALDH1A1ACHE
SCHEMBL25367938 0.79 CYP3A4 (0.57) CYP3A4ALOX15POLBALDH1A1ACHE
SCHEMBL25367786 0.77 CYP3A4 (0.67) CYP3A4ALOX15POLBALDH1A1ACHE
SCHEMBL10000333 0.77 CYP3A4 (0.43) CYP3A4ALOX15POLBALDH1A1ACHE
SCHEMBL25371015 0.77 CYP3A4 (0.67) CYP3A4ALOX15POLBALDH1A1ACHE
SCHEMBL4946422 0.76 POLB (0.53) CYP3A4ALOX15POLBALDH1A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11883418-B2 Compound TSYI-ZAC for inhibiting dengue virus infection and medicinal use thereof SYI BIOTECHNOLOGY CO., LTD. (TW) 2024-01-30 US claimed
US-20230285415-A1 COMPOUND TSYI-ZAC FOR INHIBITING DENGUE VIRUS INFECTION AND MEDICINAL USE THEREOF SYI BIOTECHNOLOGY CO., LTD. (TW) 2023-09-14 US claimed
US-11602520-B2 c-Met regulatory composition and its method for treating liver disease Greenyn Biotechnology Co., Ltd (TW) 2023-03-14 US claimed
US-20220142971-A1 C-MET REGULATORY COMPOSITION AND ITS METHOD FOR TREATING LIVER DISEASE Greenyn Biotechnology Co., Ltd (TW) 2022-05-12 US claimed
CN-113795258-A Methods and compositions for inhibiting viral infection 吉亚生技控股股份有限公司 2021-12-14 CN claimed
US-20210112832-A1 ANTRODIA CINNAMOMEA FERMENTED BROWN RICE, PREPARING METHOD AND COMPOSITION THEREOF KANG JIANN BIOTECH CO., LTD. (TW) 2021-04-22 US claimed
CN-109276563-B Application of pharmaceutical composition in preparing medicine for treating or preventing individual infection virus 珠海市鑫展生物科技有限公司 2021-04-09 CN claimed
EP-3415145-A2 METHOD FOR TREATING STROKE OR REDUCING NERVE INJURY Arjil Biotech Holding Company Limited (TW) 2018-12-19 EP claimed
US-20180353521-A1 METHOD FOR TREATING STROKE OR REDUCING NERVE INJURY Arjil Biotech Holding Company Limited (TW) 2018-12-13 US claimed
US-20180353520-A1 METHOD FOR TREATING STROKE OR REDUCING NERVE INJURY Arjil Biotech Holding Company Limited (TW) 2018-12-13 US claimed
US-20160151435-A1 PHARMACEUTICAL COMPOSITION ADJUVANT TO CHEMOTHERAPY DRUGS AND APPLICATIONS THEREOF BALAY BIOTECHNOLOGY CORPORATION (TW) 2016-06-02 US claimed
CN-104606260-A Pharmaceutical composition for assisting chemotherapy drugs and application thereof ENYANG BIOTECHNOLOGY CO LTD 2015-05-13 CN claimed
US-8791156-B2 Polyacetylene compound, an extract containing the same and application thereof NATIONAL CHUNG HSING UNIVERSITY (TW) 2014-07-29 US claimed
US-8716499-B2 Benzenoid compounds of antrodia cinnamomea, preparation and analysis method thereof KAOHSIUNG MEDICAL UNIVERSITY (TW) 2014-05-06 US claimed
US-20130150436-A1 POLYACETYLENE COMPOUND, AN EXTRACT CONTAINING THE SAME AND APPLICATION THEREOF NATIONAL CHUNG HSING UNIVERSITY (TW) 2013-06-13 US claimed
US-20120178945-A1 BENZENOID COMPOUNDS OF ANTRODIA CINNAMOMEA, PREPARATION AND ANALYSIS METHOD THEREOF KAOHSIUNG MEDICAL UNIVERSITY (TW) 2012-07-12 US claimed
US-20080103195-A1 COMPOUNDS FROM ANTRODIA CAMPHORATA FOR INHIBITING THE GROWTH OF CANCER TUMOR CELLS GOLDEN BIOTECHNOLOGY CORPORATION (TW) 2008-05-01 US claimed
CN-119488518-A Application of Antrodia camphorata compound in preparing pharmaceutical composition for treating diabetes 兰亭生物科技股份有限公司 2025-02-21 CN disclosed
US-7342137-B1 Cyclohexenone compounds from Antrodia camphorata and application thereof GOLDEN BIOTECHNOLOGY CORPORATION (TW) 2008-03-11 US disclosed
US-20060251673-A1 CULTIVATION METHOD AND APPLICATIONS FOR ANTRODIA CAMPHORATA GOLDEN BIOTECHNOLOGY CORP. (TW) 2006-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130150436-A1 POLYACETYLENE COMPOUND, AN EXTRACT CONTAINING THE SAME AND APPLICATION THEREOF CYP51A1, ACAT1, HADHA CYP3A4 274/4885ALOX15 865/4885POLB 1908/4885
US-20120178945-A1 BENZENOID COMPOUNDS OF ANTRODIA CINNAMOMEA, PREPARATION AND ANALYSIS METHOD THEREOF ACMSD, ABHD6, HRH4 CYP3A4 192/4885ALOX15 1767/4885POLB 4421/4885
US-20080103195-A1 COMPOUNDS FROM ANTRODIA CAMPHORATA FOR INHIBITING THE GROWTH OF CANCER TUMOR CELLS API5, CYP19A1, CYP11B1 CYP3A4 103/4885ALOX15 377/4885POLB 3557/4885
US-20180353520-A1 METHOD FOR TREATING STROKE OR REDUCING NERVE INJURY PMP22, NGF, NDUFB3 CYP3A4 4225/4885ALOX15 267/4885POLB 2942/4885
US-20180353521-A1 METHOD FOR TREATING STROKE OR REDUCING NERVE INJURY HAGH, DHCR7, HAAO CYP3A4 1548/4885ALOX15 30/4885POLB 3642/4885
US-20160151435-A1 PHARMACEUTICAL COMPOSITION ADJUVANT TO CHEMOTHERAPY DRUGS AND APPLICATIONS THEREOF CKMT1A; CKMT1B, ATP6V1B1, GOT1 CYP3A4 2572/4885ALOX15 787/4885POLB 38/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.