Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 5/20 | 0.60 |
| ▸ | MPL | P40238 | 4/20 | 0.59 |
| ▸ | CTRC | Q99895 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | PTPRA | P18433 | 1/20 | 0.58 |
| ▸ | PTPRB | P23467 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357249 | 1.00 | THRB (0.60) | THRBMPLCTRCCYP1A2CYP2C9 | |
| SCHEMBL9577785 | 1.00 | THRB (0.60) | THRBMPLCTRCCYP1A2CYP2C9 | |
| SCHEMBL29716528 | 0.95 | CYP1A2 (0.62) | THRBMPLCTRCCYP1A2CYP2C9 | |
| SCHEMBL10621003 | 0.95 | CYP1A2 (0.62) | THRBMPLCTRCCYP1A2CYP2C9 | |
| SCHEMBL29366329 | 0.89 | THRB (0.65) | THRBMPLCTRCCYP1A2CYP2C9 | |
| SCHEMBL31511329 | 0.89 | THRB (0.56) | THRBMPLCTRCCYP1A2CYP2C9 | |
| SCHEMBL6763835 | 0.88 | CTRB1 (0.73) | THRBMPLCTRCCYP1A2CYP2C9 | |
| SCHEMBL30049470 | 0.88 | CTRB1 (0.73) | THRBMPLCTRCCYP1A2CYP2C9 | |
| SCHEMBL5701120 | 0.88 | CTRB1 (0.73) | THRBMPLCTRCCYP1A2CYP2C9 | |
| SCHEMBL9577795 | 0.87 | CTRB1 (0.71) | THRBMPLCTRCCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11998302-B2 | Thermographic device for measurement of differential temperatures in tissue | WELWAZE MEDICAL INC. (US) | 2024-06-04 | — | — | US | disclosed |
| US-20230200662-A1 | THERMOGRAPHIC DEVICE FOR MEASUREMENT OF DIFFERENTIAL TEMPERATURES IN TISSUE | WELWAZE MEDICAL INC. (US) | 2023-06-29 | — | — | US | disclosed |
| US-11445917-B2 | Thermographic device for measurement of differential temperatures in tissue | WELWAZE MEDICAL INC. (US) | 2022-09-20 | — | — | US | disclosed |
| EP-3758592-A2 | THERMOGRAPHIC DEVICE FOR MEASUREMENT OF DIFFERENTIAL TEMPERATURES IN TISSUE | Welwaze Medical Inc. (US) | 2021-01-06 | — | — | EP | disclosed |
| US-20190209019-A1 | THERMOGRAPHIC DEVICE FOR MEASUREMENT OF DIFFERENTIAL TEMPERATURES IN TISSUE | ZICHY, MARLENE (AR) | 2019-07-11 | — | — | US | disclosed |
| WO-2019113460-A2 | THERMOGRAPHIC DEVICE FOR MEASUREMENT OF DIFFERENTIAL TEMPERATURES IN TISSUE | WELWAZE MEDICAL INC. (US) | 2019-06-13 | — | — | WO | disclosed |
| WO-2018053108-A1 | MICROPLATES AND OPEN-CHANNEL MICROFLUIDICS DEVICES INCLUDING COATED AND UNCOATED CELLOPHANE | UENAL BARIS (US) | 2018-03-22 | — | — | WO | disclosed |
| EP-0229191-B1 | FLY-ATTRACTIVE COMPOSITION | EARTH CHEMICAL CO., LTD. (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4855133-A | Composition for attracting flies | EARTH CHEMICAL COMPANY, LIMITED (JP) | 1989-08-08 | — | — | US | disclosed |
| US-4756854-A | Method and apparatus for detecting hydrocarbon fuel leaks | LOCKHEED CORPORATION (US) | 1988-07-12 | — | — | US | disclosed |
| EP-0229191-A1 | FLY-ATTRACTIVE COMPOSITION | EARTH CHEMICAL CO., LTD. (JP) | 1987-07-22 | — | — | EP | disclosed |