Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 5/20 | 0.60 |
| ▸ | MPL | P40238 | 4/20 | 0.59 |
| ▸ | CTRC | Q99895 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | PTPRA | P18433 | 1/20 | 0.58 |
| ▸ | PTPRB | P23467 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577791 | 1.00 | THRB (0.60) | THRBMPLCTRCCYP1A2CYP2C9 | |
| SCHEMBL9577785 | 1.00 | THRB (0.60) | THRBMPLCTRCCYP1A2CYP2C9 | |
| SCHEMBL29716528 | 0.95 | CYP1A2 (0.62) | THRBMPLCTRCCYP1A2CYP2C9 | |
| SCHEMBL10621003 | 0.95 | CYP1A2 (0.62) | THRBMPLCTRCCYP1A2CYP2C9 | |
| SCHEMBL29366329 | 0.89 | THRB (0.65) | THRBMPLCTRCCYP1A2CYP2C9 | |
| SCHEMBL31511329 | 0.89 | THRB (0.56) | THRBMPLCTRCCYP1A2CYP2C9 | |
| SCHEMBL6763835 | 0.88 | CTRB1 (0.73) | THRBMPLCTRCCYP1A2CYP2C9 | |
| SCHEMBL30049470 | 0.88 | CTRB1 (0.73) | THRBMPLCTRCCYP1A2CYP2C9 | |
| SCHEMBL5701120 | 0.88 | CTRB1 (0.73) | THRBMPLCTRCCYP1A2CYP2C9 | |
| SCHEMBL9577795 | 0.87 | CTRB1 (0.71) | THRBMPLCTRCCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 715 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260146175-A1 | THREE-DIMENSIONAL PRINTING WITH VISIBLE LIGHT ABSORBING DYES | PERIDOT PRINT LLC (US) | 2026-05-28 | — | — | US | claimed |
| EP-4398865-B1 | MAKEUP KIT COMPRISING AN AQUEOUS MAKEUP COMPOSITION AND A CONTINUOUS OILY-PHASE FIXING COMPOSITION WITH A HYDROPHOBIC FILM-FORMING POLYMER | OREAL (FR) | 2025-10-29 | — | — | EP | claimed |
| US-12383478-B2 | Cosmetic product for dyeing keratin fibers | KAO CORPORATION (JP) | 2025-08-12 | — | — | US | claimed |
| CN-115216030-B | PH value response type conductive hydrogel with amino acid slow release function and preparation method and application thereof | 陕西科技大学 | 2025-06-13 | — | — | CN | claimed |
| CN-119746936-A | Preparation method of foamed aluminum-based composite material for degrading acid-containing red G sewage | 北方工业大学 | 2025-04-04 | — | — | CN | claimed |
| US-20240423887-A1 | COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT | KAO CORPORATION (JP) | 2024-12-26 | — | — | US | claimed |
| CN-119108665-A | Electrolyte additive, aqueous electrolyte and zinc-based energy storage device | 清华大学深圳国际研究生院 | 2024-12-10 | — | — | CN | claimed |
| WO-2024246126-A1 | DYEING PRODUCT FOR KERATIN FIBERS COMPRISING AMMONIUM SALTS | KAO CORPORATION (JP) | 2024-12-05 | — | — | WO | claimed |
| US-20240390247-A1 | MAKEUP KIT COMPRISING AN AQUEOUS MAKEUP COMPOSITION AND A CONTINUOUS OILY-PHASE FIXING COMPOSITION WITH A HYDROPHOBIC FILM-FORMING POLYMER | L'OREAL (FR) | 2024-11-28 | — | — | US | claimed |
| CN-116289266-B | Processing technology of coordination complexing fluorine-free waterproof nylon fabric | 嘉兴学院 | 2024-10-25 | — | — | CN | claimed |
| CN-115094634-A | Method for preparing ZIF-8 modified cotton fabric and adsorption dyeing of acid dye by using method | 天津工业大学 | 2022-09-23 | — | — | CN | claimed |
| WO-2022188373-A1 | METHOD FOR DETECTING WATER-SOLUBLE ANIONIC SYNTHETIC PIGMENT IN FOOD | 广州市食品检验所（广州市酒类检测中心） | 2022-09-15 | — | — | WO | claimed |
| CN-114901058-A | Preparation method of composite film functional material based on graphene/polypyrrole nanotube 3D intercalation structure | 北京化工大学 | 2022-08-12 | — | — | CN | claimed |
| EP-2883531-B1 | Bleaching and coloring composition for hair | KAO CORP (JP) | 2022-06-15 | — | — | EP | claimed |
| CN-114487170-A | Method for detecting illegally added compounds in food | 张缤 | 2022-05-13 | — | — | CN | claimed |
| EP-3989920-A1 | ADDITIVES FOR COLORING AGENTS AND METHODS OF USE THEREOF | Living Proof, Inc. (US) | 2022-05-04 | — | — | EP | claimed |
| CN-111004414-B | Two-component intercalated hydrotalcite-like additive and application thereof in polypropylene plastics | 北京林业大学 | 2022-05-03 | — | — | CN | claimed |
| CN-114388077-A | Traditional Chinese medicine dyed material database based on micro-focusing Raman technology and application thereof in identification of traditional Chinese medicine dyed materials | 成都市食品药品检验研究院 | 2022-04-22 | — | — | CN | claimed |
| EP-3980140-A2 | LONG-TERM FIRE RETARDANT WITH CORROSION INHIBITORS AND METHODS FOR MAKING AND USING SAME | FRS Group, LLC (US) | 2022-04-13 | — | — | EP | claimed |
| CN-114222555-A | Additives for colorants and methods of use thereof | 生活实验公司 | 2022-03-22 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260146175-A1 | THREE-DIMENSIONAL PRINTING WITH VISIBLE LIGHT ABSORBING DYES | ADH1A, ADH1C, ADH5 | THRB 3218/4885MPL 4747/4885CTRC 4208/4885 |
| US-12383478-B2 | Cosmetic product for dyeing keratin fibers | KRT18, H1-2, H1-0 | THRB 2470/4885MPL 4872/4885CTRC 2961/4885 |
| US-20240423887-A1 | COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT | KRT18, COL14A1, COL1A1 | THRB 2991/4885MPL 4884/4885CTRC 2503/4885 |
| US-20240390247-A1 | MAKEUP KIT COMPRISING AN AQUEOUS MAKEUP COMPOSITION AND A CONTINUOUS OILY-PHASE FIXING COMPOSITION WITH A HYDROPHOBIC FILM-FORMING POLYMER | KRT18, CUTA, MARK1 | THRB 2470/4885MPL 4843/4885CTRC 2485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.