Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL959392 | 0.85 | NPC1 (0.44) | G6PDCASP7CASP6MMP2ALDH1A1 | |
| SCHEMBL4716508 | 0.83 | NOTUM (0.41) | G6PDCASP7CASP6NOTUMALDH1A1 | |
| SCHEMBL17227262 | 0.82 | MAPT (0.53) | ALDH1A1LMNAPOLBGAA | |
| SCHEMBL28025590 | 0.81 | G6PD (0.55) | G6PDCASP7CASP6MMP2ALDH1A1 | |
| SCHEMBL29365220 | 0.79 | ALDH1A1 (0.56) | ALDH1A1ALOX15TAS2R14NAPRTHTT | |
| SCHEMBL180853 | 0.79 | ALDH1A1 (0.56) | ALDH1A1ALOX15TAS2R14NAPRTHTT | |
| SCHEMBL12765017 | 0.79 | ALDH1A1 (0.51) | CASP7ALDH1A1LMNAPOLBTSHR | |
| SCHEMBL526919 | 0.79 | G6PD (0.74) | G6PDCASP7CASP6MMP2ALDH1A1 | |
| SCHEMBL1662301 | 0.78 | ALDH1A1 (0.52) | G6PDCASP7CASP6MMP2NOTUM | |
| SCHEMBL27869030 | 0.78 | ALDH1A1 (0.44) | G6PDCASP7CASP6NOTUMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12479809-B2 | Hydrazone amide derivative and application thereof in preparation of medicaments for preventing and treating alopecia | SHENZHEN CELL INSPIRE PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2025-11-25 | — | — | US | disclosed |
| US-12252459-B2 | Hydrazone amide derivatives and use thereof in preparation of anti-osteoporosis drugs | SHENZHEN CELL INSPIRE PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2025-03-18 | — | — | US | disclosed |
| EP-3992185-B1 | HYDRAZONE AMIDE DERIVATIVE AND APPLICATION THEREOF IN PREPARATION OF MEDICAMENTS FOR PREVENTING AND TREATING ALOPECIA | SHENZHEN CELL INSPIRE PHARMACEUTICAL DEV CO LTD (CN) | 2024-05-29 | — | — | EP | disclosed |
| EP-3992184-B1 | HYDRAZONE AMIDE DERIVATIVES AND USE THEREOF IN PREPARATION OF ANTI-OSTEOPOROSIS DRUGS | SHENZHEN CELL INSPIRE PHARMACEUTICAL DEV CO LTD (CN) | 2024-05-29 | — | — | EP | disclosed |
| CN-113105411-B | Hydrazone amide derivatives and pharmaceutical compositions | 深圳市三启药物开发有限公司 | 2023-03-17 | — | — | CN | disclosed |
| US-20220153688-A1 | HYDRAZONE AMIDE DERIVATIVES AND USE THEREOF IN PREPARATION OF ANTI-OSTEOPOROSIS DRUGS | SHENZHEN CELL INSPIRE PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2022-05-19 | — | — | US | disclosed |
| US-20220153713-A1 | HYDRAZONE AMIDE DERIVATIVE AND APPLICATION THEREOF IN PREPARATION OF MEDICAMENTS FOR PREVENTING AND TREATING ALOPECIA | SHENZHEN CELL INSPIRE PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2022-05-19 | — | — | US | disclosed |
| EP-3992184-A1 | HYDRAZONE AMIDE DERIVATIVES AND USE THEREOF IN PREPARATION OF ANTI-OSTEOPOROSIS DRUGS | Shenzhen Cell Inspire Pharmaceutical Development Co., Ltd. (CN) | 2022-05-04 | — | — | EP | disclosed |
| EP-3992185-A1 | HYDRAZONE AMIDE DERIVATIVE AND APPLICATION THEREOF IN PREPARATION OF MEDICAMENTS FOR PREVENTING AND TREATING ALOPECIA | Shenzhen Cell Inspire Pharmaceutical Development Co., Ltd. (CN) | 2022-05-04 | — | — | EP | disclosed |
| CN-113105411-A | Hydrazone amide derivatives and pharmaceutical compositions | 深圳市三启药物开发有限公司 | 2021-07-13 | — | — | CN | disclosed |
| EP-1771070-A1 | MIXTURES OF ANTHRANILAMIDE INVERTEBRATE PEST CONTROL AGENTS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006068669-A1 | MIXTURES OF ANTHRANILAMIDE INVERTEBRATE PEST CONTROL AGENTS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-06-29 | — | — | WO | disclosed |
| US-20060111403-A1 | Cyano anthranilamide insecticides | FMC CORPORATION | 2006-05-25 | — | — | US | disclosed |
| WO-2006023783-A1 | NOVEL ANTHRANILAMIDES USEFUL FOR CONTROLLING INVERTEBRATE PESTS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-03-02 | — | — | WO | disclosed |
| EP-1599463-A1 | CYANO ANTHRANILAMIDE INSECTICIDES | E.I. du Pont de Nemours and Company (US) | 2005-11-30 | — | — | EP | disclosed |
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | disclosed |
| WO-2004067528-A1 | CYANO ANTHRANILAMIDE INSECTICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-08-12 | — | — | WO | disclosed |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | G6PD 418/4885CASP7 191/4885CASP6 214/4885 |
| US-20060111403-A1 | Cyano anthranilamide insecticides | C1S, C5, CBR3 | G6PD 3719/4885CASP7 2091/4885CASP6 1978/4885 |
| US-12479809-B2 | Hydrazone amide derivative and application thereof in preparation of medicaments for preventing and treating alopecia | FH, HDGF, HRH4 | G6PD 3229/4885CASP7 992/4885CASP6 2540/4885 |
| US-12252459-B2 | Hydrazone amide derivatives and use thereof in preparation of anti-osteoporosis drugs | SOST, HDAC5, PTH1R | G6PD 1667/4885CASP7 1539/4885CASP6 3237/4885 |
| US-20220153688-A1 | HYDRAZONE AMIDE DERIVATIVES AND USE THEREOF IN PREPARATION OF ANTI-OSTEOPOROSIS DRUGS | SOST, HDAC5, PTH1R | G6PD 1667/4885CASP7 1539/4885CASP6 3237/4885 |
| US-20220153713-A1 | HYDRAZONE AMIDE DERIVATIVE AND APPLICATION THEREOF IN PREPARATION OF MEDICAMENTS FOR PREVENTING AND TREATING ALOPECIA | FH, HDGF, HRH4 | G6PD 3229/4885CASP7 992/4885CASP6 2540/4885 |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | G6PD 1286/4885CASP7 141/4885CASP6 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.