Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711474 | 0.86 | HSD11B1 (0.42) | — | |
| SCHEMBL9711470 | 0.85 | EPHX1 (0.43) | NPC1RAB9AKMT2ASMN1; SMN2PARP1 | |
| SCHEMBL9711454 | 0.84 | MAPT (0.44) | HTTKMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9711528 | 0.82 | F2RL1 (0.42) | NPC1RAB9AHTTKMT2ASMN1; SMN2 | |
| SCHEMBL9711523 | 0.82 | SLC6A3 (0.40) | KMT2APARP1KDM2BALDH1A1 | |
| SCHEMBL9711648 | 0.80 | CES2 (0.43) | CES2HTTKMT2ASMN1; SMN2KCNK3 | |
| SCHEMBL9711582 | 0.79 | LMNA (0.49) | CES2CES1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL9711510 | 0.78 | MAPT (0.43) | NPC1RAB9AHTTKMT2ASMN1; SMN2 | |
| SCHEMBL9711698 | 0.78 | KMO (0.43) | TSHR | |
| SCHEMBL9711787 | 0.78 | LDHA (0.41) | NPC1RAB9AHTTSMN1; SMN2KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |