SCHEMBL9728461

SCHEMBL9728461

COC(CN1CC=CN(c2ccccc2)N1)OC

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.35
CFTR P13569 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9728500 0.77 ADRA2A (0.46) CFTR
SCHEMBL9728348 0.70 SMN1; SMN2 (0.37) CFTR
SCHEMBL10961509 0.69 LMNA (0.44) CFTR
SCHEMBL9728417 0.68 L3MBTL1 (0.43) TDP1
SCHEMBL3192879 0.68 CFTR (0.39) CFTR
SCHEMBL1230085 0.61 CFTR (0.59) CFTR
SCHEMBL16361382 0.61 SIGMAR1 (0.40) TDP1CFTR
SCHEMBL9728456 0.60 TDP1 (0.35) TDP1
SCHEMBL9154795 0.56 G6PD (0.41)
SCHEMBL11221060 0.55 CFTR (0.54) TDP1CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5098926-A Antitumor agents UNIVERSITY PATENTS, INC. (US) 1992-03-24 US disclosed
US-4888341-A 6-substituted mitomycin analogs UNIVERSITY PATENTS, INC. (US) 1989-12-19 US disclosed