Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.30 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.30 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.30 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733284 | 0.86 | HTR1A (0.37) | ALDH1A1KMT2APGRABCC9ABCC8 | |
| SCHEMBL9733727 | 0.82 | PDE4B (0.36) | ALDH1A1PGRTSHR | |
| SCHEMBL9733746 | 0.79 | PGR (0.34) | PGRABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9733106 | 0.79 | PGR (0.34) | PGR | |
| SCHEMBL9734356 | 0.79 | POLB (0.34) | ALDH1A1KMT2APGR | |
| SCHEMBL9733259 | 0.79 | PGR (0.34) | PGRABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9733353 | 0.78 | CHRM1 (0.37) | ALDH1A1KMT2APGRSMN1; SMN2 | |
| SCHEMBL9732964 | 0.77 | DRD2 (0.35) | PGR | |
| SCHEMBL9733561 | 0.77 | PGR (0.36) | ALDH1A1KMT2APGRABCC9ABCC8 | |
| SCHEMBL9733975 | 0.76 | KCNH2 (0.37) | KMT2APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132307-A | TETRALIN COMPOUNDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-21 | — | — | US | disclosed |
| EP-0368160-A1 | Tetralin derivatives | MERCK PATENT GmbH (DE) | 1990-05-16 | — | — | EP | disclosed |