Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9791608 | 0.73 | FAAH (0.45) | FAAHNPSR1MAPTLMNAL3MBTL1 | |
| 3-Phenethylphenol SCHEMBL717571 | 0.63 | OPRK1 (0.74) | OPRK1OPRM1OPRD1DRD2DRD3 | |
| SCHEMBL9782162 | 0.62 | PTGS2 (0.49) | OPRK1OPRM1OPRD1DRD2MAPT | |
| SCHEMBL9452944 | 0.62 | RXRA (0.57) | DRD2DRD3MAPK1LMNA | |
| SCHEMBL723832 | 0.61 | DRD2 (0.74) | OPRK1OPRM1OPRD1CALM1DRD2 | |
| Phenol SCHEMBL1236990 | 0.61 | OPRK1 (0.65) | OPRK1OPRM1OPRD1DRD2DRD3 | |
| SCHEMBL23105432 | 0.60 | FAAH (0.50) | FAAHMAPTMAPK1ATMTDP1 | |
| SCHEMBL9064286 | 0.59 | OPRK1 (0.53) | OPRK1OPRM1OPRD1CALM1DRD2 | |
| SCHEMBL24427083 | 0.59 | ALDH1A1 (0.47) | FAAHMAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL216654 | 0.58 | DRD2 (0.67) | OPRK1OPRM1OPRD1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442448-A2 | Heterocyclic carboxylic acids and esters | Bristol-Myers Squibb Company (US) | 1991-08-21 | — | — | EP | disclosed |
| US-5011851-A | Imidazole carboxylic acids and esters and inhibition of blood platelet aggregation therewith | BRISTOL-MYERS SQUIBB CO. (US) | 1991-04-30 | — | — | US | disclosed |