Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799824 | 0.88 | NPC1 (0.35) | L3MBTL1NPC1KCNH2 | |
| SCHEMBL9799796 | 0.80 | ALDH1A1 (0.40) | MAPTSMN1; SMN2 | |
| SCHEMBL9833650 | 0.79 | MAPT (0.41) | L3MBTL1MAPTNPC1RAB9ALMNA | |
| SCHEMBL9799313 | 0.78 | TUBB4A (0.38) | L3MBTL1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9799293 | 0.76 | FDPS (0.38) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9832379 | 0.68 | NPC1 (0.35) | MAPTNPC1RAB9A | |
| SCHEMBL9799434 | 0.66 | MEN1 (0.38) | L3MBTL1NPC1RAB9ASMN1; SMN2KCNH2 | |
| SCHEMBL9799541 | 0.64 | PTGS2 (0.39) | L3MBTL1MAPTSMN1; SMN2LMNAALOX15 | |
| SCHEMBL9799280 | 0.63 | SIGMAR1 (0.40) | NPC1KCNH2FDPS | |
| SCHEMBL8154724 | 0.63 | TAAR1 (0.47) | KCNH2FDPSGPR84IGF1RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298703-B1 | A THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| US-4946862-A | Thiophene derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0298703-A1 | A thiophene derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-01-11 | — | — | EP | disclosed |