Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.48 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.48 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.42 |
| ▸ | FGF1 known ✓ | P05230 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DUSP5 | Q16690 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | IL1RN | P18510 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30785961 | 1.00 | CA2 (0.48) | CA2CA4LMNATDP1CA1 | |
| Potassium Ion SCHEMBL31530533 | 0.96 | CA2 (0.43) | CA2CA4LMNATDP1CA1 | |
| Terephthalic Acid SCHEMBL8053920 | 0.87 | CA2 (0.48) | CA2CA4CA1DUSP5PTPN1 | |
| SCHEMBL5079232 | 0.86 | LMNA (0.53) | CA2LMNATDP1CA1F2 | |
| Tetraphenylphosphonium SCHEMBL31425587 | 0.85 | CA2 (0.43) | CA2CA4TDP1CA1F2 | |
| SCHEMBL1356070 | 0.85 | TSHR (0.50) | CA2CA4LMNATDP1CA1 | |
| SCHEMBL2365675 | 0.85 | TSHR (0.50) | CA2CA4LMNATDP1CA1 | |
| SCHEMBL39401 | 0.85 | F2 (0.56) | CA2CA1F2PRSS1PRSS2 | |
| SCHEMBL30479405 | 0.85 | F2 (0.56) | CA2CA1F2PRSS1PRSS2 | |
| Isophthalic Acid SCHEMBL1396767 | 0.84 | CA2 (0.56) | CA2CA4TDP1CA1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222647-B1 | POLYESTER, METHOD FOR THEIR PREPARATION AND THEIR USE | WEYLCHEM WIESBADEN GMBH (DE) | 2018-10-17 | — | — | EP | claimed |
| US-20170275420-A1 | Polyesters, Manufacturing Process Thereof and Their Use | WEYLCHEM WIESBADEN GMBH (DE) | 2017-09-28 | — | — | US | claimed |
| US-7875694-B2 | reacting a sulfobenzoic acid cyclic anhydride or sulfobenzoic acid sodium salt with amine functional siloxane; emulsion; useful in a variety of personal, household, healthcare formulations, as well as fabric and textile treatments; produced by a safer route | DOW CORNING CORPORATION (US) | 2011-01-25 | — | — | US | claimed |
| US-20090043069-A1 | ACTIVATED ESTERS FOR SYNTHESIS OF SULFONATED TELECHELIC POLYCARBONATES | GENERAL ELECTRIC COMPANY (US) | 2009-02-12 | — | — | US | claimed |
| WO-2009020967-A1 | ACTIVATED ESTERS FOR SYNTHESIS OF SULFONATED TELECHELIC POLYCARBONATES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-02-12 | — | — | WO | claimed |
| EP-1824905-B1 | SULFONATE FUNCTIONAL ORGANOPOLYSILOXANES | DOW CORNING (US) | 2008-11-26 | — | — | EP | claimed |
| US-20070299140-A1 | reacting a sulfobenzoic acid cyclic anhydride or sulfobenzoic acid sodium salt with amine functional siloxane; emulsion; useful in a variety of personal, household, healthcare formulations, as well as fabric and textile treatments; produced by a safer route | KENNAN JOHN J | 2007-12-27 | — | — | US | claimed |
| EP-1824905-A2 | SULFONATE FUNCTIONAL ORGANOPOLYSILOXANES | Dow Corning Corporation (US) | 2007-08-29 | — | — | EP | claimed |
| WO-2006065467-A2 | SULFONATE FUNCTIONAL ORGANOPOLYSILOXANES | DOW CORNING CORPORATION (US) | 2006-06-22 | — | — | WO | claimed |
| EP-3986974-B1 | SILICATE BASED HEAT TRANSFER FLUID, METHODS OF ITS PREPARATIONS AND USES THEREOF | ARTECO NV (BE) | 2023-07-26 | — | — | EP | disclosed |
| US-20230167227-A1 | AQUEOUS DISPERSION OF POLY(ESTER-URETHANE) OR OF POLY(ESTER-URETHANE-UREA) | ARKEMA FRANCE (FR) | 2023-06-01 | — | — | US | disclosed |
| US-11643501-B2 | Oxidizing, ionic and short oil alkyd resins for coatings with excellent balance of hardness and gloss | COVESTRO (NETHERLANDS) B.V. (NL) | 2023-05-09 | — | — | US | disclosed |
| CN-115715304-A | Aqueous dispersions of poly (ester-urethane) or poly (ester-urethane-urea) | 阿科玛法国公司 | 2023-02-24 | — | — | CN | disclosed |
| US-20220306925-A1 | Silicate based heat transfer fluid, methods of its preparations and uses thereof | Arteco N.v. (BE) | 2022-09-29 | — | — | US | disclosed |
| EP-0547106-B1 | IMPROVED SOIL RELEASE AGENTS FOR GRANULAR LAUNDRY DETERGENTS | PROCTER & GAMBLE (US) | 1995-12-27 | — | — | EP | disclosed |
| EP-0356902-B1 | Polyesters with modified melt viscosity | GEN ELECTRIC (US) | 1995-11-22 | — | — | EP | disclosed |
| EP-0679941-A2 | Sulfo-substituted carboxylates as buffers for photographic bleaches and bleach-fixes | EASTMAN KODAK COMPANY (US) | 1995-11-02 | — | — | EP | disclosed |
| EP-0547106-A1 | IMPROVED SOIL RELEASE AGENTS FOR GRANULAR LAUNDRY DETERGENTS. | PROCTER & GAMBLE (US) | 1993-06-23 | — | — | EP | disclosed |
| WO-1992004433-A1 | IMPROVED SOIL RELEASE AGENTS FOR GRANULAR LAUNDRY DETERGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |
| EP-0356902-A2 | Polyesters with modified melt viscosity | GENERAL ELECTRIC COMPANY (US) | 1990-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299140-A1 | reacting a sulfobenzoic acid cyclic anhydride or sulfobenzoic acid sodium salt with amine functional siloxane; emulsion; useful in a variety of personal, household, healthcare formulations, as well as fabric and textile treatments; produced by a safer route | STS, USP21, SCLY | CA2 494/4885CA4 302/4885CA1 359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.