SCHEMBL9916896

SCHEMBL9916896

CC1(C)c2ccccc2-c2ccc(N(c3ccc(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)cc3)c3ccc4oc5ccccc5c4c3)cc21

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TSPO P30536 1/20 0.32
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9916875 1.00 KDM4E (0.32) KDM4EATML3MBTL1TSPOHSP90AA1
SCHEMBL9916913 1.00 KDM4E (0.32) KDM4EATML3MBTL1TSPOHSP90AA1
SCHEMBL9916873 0.99 KDM4E (0.32) KDM4EATML3MBTL1TSPOHSP90AA1
SCHEMBL9916431 0.99 KDM4E (0.32) KDM4EATML3MBTL1TSPOHSP90AA1
SCHEMBL9916878 0.99 KDM4E (0.32) KDM4EATML3MBTL1TSPOHSP90AA1
SCHEMBL9916882 0.98 KDM4E (0.32) KDM4EATML3MBTL1TSPOHSP90AA1
SCHEMBL10040800 0.97 TSPO (0.33) TSPO
SCHEMBL15762310 0.97 PLA2G2A (0.31) TSPOHSP90AA1HSP90AB1
SCHEMBL20935704 0.97 TSPO (0.34) KDM4EATML3MBTL1TSPO
SCHEMBL30570866 0.97 TSPO (0.34) KDM4EATML3MBTL1TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 US disclosed
US-11659763-B2 Metal complexes MERCK PATENT GMBH 2023-05-23 US disclosed
US-11659763-B2 Metal complexes MERCK PATENT GMBH 2023-05-23 US disclosed
US-20230118826-A1 ORGANIC LIGHT-EMITTING DEVICE SFC CO., LTD (KR) 2023-04-20 US disclosed
US-11569458-B2 Metal complexes MERCK PATENT GMBH (DE) 2023-01-31 US disclosed
US-11535640-B2 Metal complexes MERCK PATENT GMBH (DE) 2022-12-27 US disclosed
US-11335858-B2 Aromatic amine derivatives and organic electroluminescent elements using same IDEMITSU KOSAN CO., LTD. (JP) 2022-05-17 US disclosed
US-20160064669-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-03-03 US disclosed
US-20160064669-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-03-03 US disclosed
US-9260390-B2 Aromatic amine derivatives and organic electroluminescent elements using same IDEMITSU KOSAN CO., LTD. (JP) 2016-02-16 US disclosed
US-9260390-B2 Aromatic amine derivatives and organic electroluminescent elements using same IDEMITSU KOSAN CO., LTD. (JP) 2016-02-16 US disclosed
US-20140070199-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE LIGHT EMITTING DIODE JUNG SUNG-HYUN (KR) 2014-03-13 US disclosed
US-20140070199-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE LIGHT EMITTING DIODE JUNG SUNG-HYUN (KR) 2014-03-13 US disclosed
US-20120146014-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-06-14 US disclosed
US-20120146014-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-06-14 US disclosed
US-20120043531-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2012-02-23 US disclosed
US-20120043531-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2012-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320191-A1 METAL COMPLEXES IMMT, MCU, SOD1 KDM4E 4470/4885ATM 4048/4885L3MBTL1 3259/4885
US-20120146014-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME PNMT, TYR, AOC2 KDM4E 141/4885ATM 1490/4885L3MBTL1 631/4885
US-20160064669-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME PNMT, TYR, AOC2 KDM4E 141/4885ATM 1490/4885L3MBTL1 631/4885
US-11535640-B2 Metal complexes IMMT, MCU, SOD1 KDM4E 4470/4885ATM 4048/4885L3MBTL1 3259/4885
US-20120043531-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE LIGHT EMITTING DIODE AOX1, OR10J3, OCIAD1 KDM4E 2976/4885ATM 3554/4885L3MBTL1 1452/4885
US-11659763-B2 Metal complexes IMMT, MCU, SOD1 KDM4E 4470/4885ATM 4048/4885L3MBTL1 3259/4885
US-11569458-B2 Metal complexes IMMT, MCU, SOD1 KDM4E 4470/4885ATM 4048/4885L3MBTL1 3259/4885
US-11917903-B2 Metal complexes NCLN, BICRA, AP3M1 KDM4E 3870/4885ATM 3416/4885L3MBTL1 2532/4885
US-11335858-B2 Aromatic amine derivatives and organic electroluminescent elements using same RER1, NR4A1, REL KDM4E 1053/4885ATM 3001/4885L3MBTL1 1556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.